Expanding the Alkaline Phosphatase Inhibition, Cytotoxic and Proapoptotic Profile of Biscoumarin‐Iminothiazole and Coumarin‐Triazolothiadiazine Conjugates

2018 ◽  
Vol 3 (47) ◽  
pp. 13377-13386
Author(s):  
Jamshed Iqbal ◽  
Syeda Abida Ejaz ◽  
Aliya Ibrar ◽  
Muhammad Ihtisham Umar ◽  
Joanna Lecka ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Phosphatase Inhibition ◽  
Alkaline Phosphatase Inhibition

Synthesis, alkaline phosphatase inhibition studies and molecular docking of novel derivatives of 4-quinolones

2017 ◽  
Vol 126 ◽  
pp. 408-420 ◽  
Author(s):  
Mariia Miliutina ◽  
Syeda Abida Ejaz ◽  
Shafi Ullah Khan ◽  
Viktor O. Iaroshenko ◽  
Alexander Villinger ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Molecular Docking ◽  
Phosphatase Inhibition ◽  
Inhibition Studies ◽  
Derivatives Of ◽  
Alkaline Phosphatase Inhibition

Facile and expedient access to bis-coumarin–iminothiazole hybrids by molecular hybridization approach: synthesis, molecular modelling and assessment of alkaline phosphatase inhibition, anticancer and antileishmanial potential

RSC Advances ◽  
2015 ◽  
Vol 5 (109) ◽  
pp. 89919-89931 ◽  
Author(s):  
Aliya Ibrar ◽  
Sumera Zaib ◽  
Imtiaz Khan ◽  
Farukh Jabeen ◽  
Jamshed Iqbal ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Molecular Modelling ◽  
Molecular Hybridization ◽  
Phosphatase Inhibition ◽  
Potential Inhibitors ◽  
Alkaline Phosphatase Inhibition

A series of new cytotoxic bis-coumarin–iminothiazole hybrids was developed as potential inhibitors of alkaline phosphatase and leishmaniasis.

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