Asymmetric Transfer Hydrogenation of Cyclic Imines in Water with a Versatile Hydrogen Donor Formic Acid/N-Methylpiperidine: Rapid Access to Highly Enantioselective Amines

2016 ◽  
Vol 1 (10) ◽  
pp. 2221-2224 ◽  
Author(s):  
Vaishali S. Shende ◽  
Savita K. Shingote ◽  
Sudhindra H. Deshpande ◽  
Ashutosh. A. Kelkar
Keyword(s):  
Formic Acid ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Rapid Access

Rhodium-Catalyzed anti and syn Enantio- and Diastereoselective Transfer Hydrogenation of α-Amino β-Keto Ester Hydrochlorides through Dynamic Kinetic Resolution

Synthesis ◽  
2016 ◽  
Vol 48 (19) ◽  
pp. 3357-3363 ◽  
Author(s):  
Quentin Llopis ◽  
Charlène Férard ◽  
Gérard Guillamot ◽  
Phannarath Phansavath ◽  
Virginie Ratovelomanana-Vidal
Keyword(s):  
Formic Acid ◽  
Kinetic Resolution ◽  
Amino Alcohols ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Dynamic Kinetic Resolution ◽  
Keto Ester ◽  
Catalytic Asymmetric ◽  
Donor Source

A mild catalytic asymmetric transfer hydrogenation of a series of α-amino β-keto ester hydrochlorides catalyzed by a rhodium(III) complex is reported. The use of the formic acid/triethylamine system as the hydrogen donor source provided the corresponding anti and syn amino alcohols with complete conversions, fair diastereoselectivities (up to 97:3 dr), and high enantioselectivities (ee up to >99%).

Rhodium-catalyzed asymmetric transfer hydrogenation of 4-quinolone derivatives

2020 ◽  
Vol 7 (8) ◽  
pp. 975-979 ◽  
Author(s):  
Bin He ◽  
Phannarath Phansavath ◽  
Virginie Ratovelomanana-Vidal
Keyword(s):  
Formic Acid ◽  
Transfer Hydrogenation ◽  
Rhodium Complex ◽  
Asymmetric Transfer Hydrogenation ◽  
Quinolone Derivatives

4-Quinolone derivatives were conveniently reduced to 1,2,3,4-tetrahydroquinoline-4-ols with excellent enantioselectivities through asymmetric transfer hydrogenation using a tethered rhodium complex and formic acid/triethylamine as the hydride source.

A Recyclable Catalyst for Asymmetric Transfer Hydrogenation with a Formic Acid—Triethylamine Mixture in Ionic Liquid.

ChemInform ◽  
2005 ◽  
Vol 36 (37) ◽  
Author(s):  
Ikuo Kawasaki ◽  
Kazuya Tsunoda ◽  
Tomoko Tsuji ◽  
Tomoko Yamaguchi ◽  
Hiroki Shibuta ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Formic Acid ◽  
Recyclable Catalyst ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation

scholarly journals Manganese Catalyzed Asymmetric Transfer Hydrogenation of Ketones Using Chiral Oxamide Ligands

Synlett ◽  
2019 ◽  
Vol 30 (04) ◽  
pp. 503-507 ◽  
Author(s):  
Jacob Schneekönig ◽  
Kathrin Junge ◽  
Matthias Beller
Keyword(s):  
Isopropyl Alcohol ◽  
Ruthenium Catalyst ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation ◽  
Reaction Conditions ◽  
Active Systems ◽  
Manganese Catalysts

The asymmetric transfer hydrogenation of ketones using isopropyl alcohol (IPA) as hydrogen donor in the presence of novel manganese catalysts is explored. The selective and active systems are easily generated in situ from [MnBr(CO)5] and inexpensive C 2-symmeric bisoxalamide ligands. Under the optimized reaction conditions, the Mn-derived catalyst gave higher enantioselectivity compared with the related ruthenium catalyst.

Magnesium Aluminate Supported Cu Catalyst for Selective Transfer Hydrogenation of Biomass Derived Furfural to Furfuryl Alcohol with Formic Acid as Hydrogen Donor

2019 ◽  
Vol 4 (1) ◽  
pp. 145-151 ◽  
Author(s):  
Peddinti Nagaiah ◽  
Paleti Gidyonu ◽  
Muppala Ashokraju ◽  
Madduluri Venkata Rao ◽  
Prathap Challa ◽  
...  
Keyword(s):  
Formic Acid ◽  
Furfuryl Alcohol ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Magnesium Aluminate ◽  
Selective Transfer ◽  
Cu Catalyst

Asymmetric transfer hydrogenation of imines in water/methanol co-solvent system and mechanistic investigation by DFT study

RSC Advances ◽  
2014 ◽  
Vol 4 (86) ◽  
pp. 46351-46356 ◽  
Author(s):  
Vaishali S. Shende ◽  
Savita K. Shingote ◽  
Sudhindra H. Deshpande ◽  
Nishamol Kuriakose ◽  
Kumar Vanka ◽  
...  
Keyword(s):  
Solvent System ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Dft Study ◽  
Asymmetric Transfer Hydrogenation ◽  
Mechanistic Investigation

Asymmetric transfer hydrogenation of various cyclic imines proceeded efficiently with H2O/MeOH (1 : 1, v/v) co-solvent media in 20 min with excellent yields and enantioselectivities by using Rh–TsDPEN catalyst and HCOONa as a hydrogen donor.

scholarly journals Nickel-catalyzed asymmetric transfer hydrogenation of conjugated olefins

2015 ◽  
Vol 51 (60) ◽  
pp. 12115-12117 ◽  
Author(s):  
Siyu Guo ◽  
Peng Yang ◽  
Jianrong (Steve) Zhou
Keyword(s):  
Formic Acid ◽  
Nickel Catalyst ◽  
Asymmetric Hydrogenation ◽  
Transfer Hydrogenation ◽  
Asymmetric Transfer Hydrogenation

A nickel catalyst is used for asymmetric hydrogenation of electron-deficient olefins using formic acid as hydrogen source.

Efficient asymmetric transfer hydrogenation of ketones in ethanol with chiral iridium complexes of spiroPAP ligands as catalysts

2015 ◽  
Vol 51 (28) ◽  
pp. 6123-6125 ◽  
Author(s):  
Wei-Peng Liu ◽  
Ming-Lei Yuan ◽  
Xiao-Hui Yang ◽  
Ke Li ◽  
Jian-Hua Xie ◽  
...  
Keyword(s):  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Chiral Alcohols ◽  
Iridium Complexes ◽  
Asymmetric Transfer Hydrogenation ◽  
Highly Efficient

Highly efficient iridium catalyzed asymmetric transfer hydrogenation of simple ketones with ethanol as a hydrogen donor has been developed, providing chiral alcohols with up to 98% ee.

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