scholarly journals The dual role of platelet-innate immune cell interactions in thrombo-inflammation

2019 ◽  
Vol 4 (1) ◽  
pp. 23-35 ◽  
Author(s):  
Julie Rayes ◽  
Joshua H. Bourne ◽  
Alexander Brill ◽  
Steve P. Watson
Keyword(s):  
Immune Cell ◽  
Dual Role ◽  
Innate Immune ◽  
Cell Interactions ◽  
Innate Immune Cell

scholarly journals Critical Role of Zinc Transporter (ZIP8) in Myeloid Innate Immune Cell Function and the Host Response against Bacterial Pneumonia

2021 ◽  
pp. ji2001395
Author(s):  
Sannette C. Hall ◽  
Deandra R. Smith ◽  
Shetty Ravi Dyavar ◽  
Todd A. Wyatt ◽  
Derrick R. Samuelson ◽  
...  
Keyword(s):  
Host Response ◽  
Bacterial Pneumonia ◽  
Cell Function ◽  
Immune Cell ◽  
Critical Role ◽  
Zinc Transporter ◽  
Innate Immune ◽  
Innate Immune Cell ◽  
Immune Cell Function

Regulatory role of periodontal ligament fibroblasts for innate immune cell function and differentiation

2012 ◽  
Vol 18 (5) ◽  
pp. 745-752 ◽  
Author(s):  
Anna Konermann ◽  
Dirk Stabenow ◽  
Percy A Knolle ◽  
Stefanie AE Held ◽  
James Deschner ◽  
...  
Keyword(s):  
Periodontal Ligament ◽  
Cell Function ◽  
Immune Cell ◽  
Innate Immune ◽  
Innate Immune Cell ◽  
Regulatory Role ◽  
Immune Cell Function ◽  
Periodontal Ligament Fibroblasts

scholarly journals Megakaryocytes Display Innate Immune Cell Functions and Respond during Sepsis

2019 ◽  
Author(s):  
Galit H. Frydman ◽  
Felix Ellett ◽  
Julianne Jorgensen ◽  
Anika L. Marand ◽  
Lawrence Zukerberg ◽  
...  
Keyword(s):  
Immune Cell ◽  
Leukemia Cell ◽  
Peripheral Circulation ◽  
Innate Immune ◽  
Innate Immune Cell ◽  
Leukemia Cell Line ◽  
Megakaryoblastic Leukemia ◽  
Cell Functions

AbstractMegakaryocytes (MKs) are precursors to platelets, the second most abundant cells in the peripheral circulation. However, while platelets are known participate in immune responses and play significant roles during infections, the role of MKs within the immune system has not been explored. Here we utilizein vitrotechniques to show that both cord blood-derived MKs (CB MKs) and MKs from a human megakaryoblastic leukemia cell line (Meg-01) chemotax towards pathogenic stimuli, phagocytose bacteria, and release chromatin webs in response to bacteria. Moreover, in patients with sepsis, we found that MK counts were significantly higher in the peripheral blood, and CD61+staining was increased in the kidneys and lungs, correlated with the development of organ dysfunction. Overall, our study suggests that MK cells display basic innate immune cell functions and respond during infections and sepsis.

MSC and innate immune cell interactions: A lesson from human decidua

2015 ◽  
Vol 168 (2) ◽  
pp. 170-174 ◽  
Author(s):  
Paola Vacca ◽  
Elisa Montaldo ◽  
Chiara Vitale ◽  
Daniele Croxatto ◽  
Lorenzo Moretta ◽  
...  
Keyword(s):  
Immune Cell ◽  
Innate Immune ◽  
Cell Interactions ◽  
Innate Immune Cell ◽  
Human Decidua

scholarly journals The Role of TRPV4 in Regulating Innate Immune Cell Function in Lung Inflammation

2020 ◽  
Vol 11 ◽  
Author(s):  
Rachel G. Scheraga ◽  
Brian D. Southern ◽  
Lisa M. Grove ◽  
Mitchell A. Olman
Keyword(s):  
Lung Inflammation ◽  
Cell Function ◽  
Immune Cell ◽  
Innate Immune ◽  
Innate Immune Cell ◽  
Immune Cell Function
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