Robust nonlinear H  ∞  control based on the L2 incremental gain

2014 ◽  
Vol 25 (8) ◽  
pp. 1183-1200 ◽  
Author(s):  
Hossein Beikzadeh ◽  
Horacio J. Marquez
Keyword(s):  
Incremental Gain

scholarly journals Voyager: A Retrospective

1992 ◽  
Vol 9 ◽  
pp. 33-42
Author(s):  
Bradford A. Smith
Keyword(s):  
Solar System ◽  
Giant Planets ◽  
Space Program ◽  
Remote Region ◽  
Outer Planets ◽  
New Information ◽  
Incremental Gain ◽  
The Many

AbstractWithin the brief span of a decade, from 1979 to 1989, the Voyager spacecraft visited the four giant planets – Jupiter, Saturn, Uranus and Neptune – along with their satellites and their rings. The science return from these two spacecraft forever changed our views of this remote region of our solar system. Often overlooked, however, is the incremental gain in knowledge from these encounters over that which had been known in the early 1970s when the Voyager project first came into being. From a post-Voyager perspective, it is astonishing how little was known about the outer planets just a mere two decades ago. Yet, with all of the knowledge that the space program has brought us, there remain a number of unanswered questions and a great many new ones that have been posed as a result of this wealth of new information. Discussed here is summary of the results of the Voyager imaging cameras together with some of the many new questions that subsequently have been raised.

Randomized Trial of Hyperthermia and Radiation for Superficial Tumors

2005 ◽  
Vol 23 (13) ◽  
pp. 3079-3085 ◽  
Author(s):  
Ellen L. Jones ◽  
James R. Oleson ◽  
Leonard R. Prosnitz ◽  
Thaddeus V. Samulski ◽  
Zeljko Vujaskovic ◽  
...  
Keyword(s):  
Randomized Trial ◽  
Local Control ◽  
Randomized Clinical Trials ◽  
Response Rate ◽  
Complete Response Rate ◽  
Test Dose ◽  
Complete Response ◽  
Thermal Dose ◽  
Incremental Gain ◽  
Overall Survival Benefit

Purpose Randomized clinical trials have demonstrated hyperthermia (HT) enhances radiation response. These trials, however, generally lacked rigorous thermal dose prescription and administration. We report the final results of a prospective randomized trial of superficial tumors (≤ 3 cm depth) comparing radiotherapy versus HT combined with radiotherapy, using the parameter describing the number of cumulative equivalent minutes at 43°C exceeded by 90% of monitored points within the tumor (CEM 43°C T90) as a measure of thermal dose. Methods This trial was designed to test whether a thermal dose of more than 10 CEM 43°C T90 results in improved complete response and duration of local control compared with a thermal dose of ≤ 1 CEM 43°C T90. Patients received a test dose of HT ≤ 1 CEM 43°C T90 and tumors deemed heatable were randomly assigned to additional HT versus no additional HT. HT was given using microwave spiral strip applicators operating at 433 MHz. Results One hundred twenty-two patients were enrolled; 109 (89%) were deemed heatable and were randomly assigned. The complete response rate was 66.1% in the HT arm and 42.3% in the no-HT arm. The odds ratio for complete response was 2.7 (95% CI, 1.2 to 5.8; P = .02). Previously irradiated patients had the greatest incremental gain in complete response: 23.5% in the no-HT arm versus 68.2% in the HT arm. No overall survival benefit was seen. Conclusion Adjuvant hyperthermia with a thermal dose more than 10 CEM 43°C T90 confers a significant local control benefit in patients with superficial tumors receiving radiation therapy.

Assessing area, production and return with rice varieties of NRRI, Cuttack

2019 ◽  
Vol 56 (Special Issue) ◽  
pp. 169-173 ◽  
Author(s):  
H Pathak ◽  
SK Pradhan ◽  
Biswajit Mondal ◽  
NN Jambhulkar ◽  
C Parameswaran ◽  
...  
Keyword(s):  
Farm Income ◽  
Total Production ◽  
Rice Varieties ◽  
Rice Area ◽  
Present Study Area ◽  
Incremental Gain ◽  
Breeder Seed ◽  
Private Entrepreneurs ◽  
High Yielding Varieties ◽  
On Farm

The ICAR-National Rice Research Institute (NRRI), Cuttack in Odisha develops varieties and agro-technologies for enhancing and sustaining rice production. The Institute so far has released 133 high-yielding varieties of rice for various ecosystems. Some of the varieties have been very popular among the farmers and even became ruling varieties in some states. However, there are no reports on the area covered by NRRI varieties and its impact on incremental gain in farm income. In the present study, area covered by NRRI varieties in the country during 2017-18 was estimated based on the amount of quality seeds provided to the farmers through various ways: breeder seed indent to the DAC; breeder seed and truthfully-labeled seed supplied by the NRRI farm; participatory seed production by NRRI; seed distributed in various programmes and projects of the Institute; front-line demonstrations and on-farm testing; seed of NRRI varieties supplied by the private entrepreneurs and disseminated from farmers to farmers etc. A validation exercise was conducted to cross-check the estimated areas under NRRI varieties. The analysis showed that currently NRRI varieties cover about 8.0 million ha (Mha) i.e., 18% of rice area of the country. West Bengal has the largest area of 2.26 Mha, followed by Odisha with 2.18 Mha. Total production of rice with NRRI varieties is 27.80 million tons (Mt) with the value of Rs.48,643 crores per annum. Further, incremental production and income with NRRI varieties considering 5% more than the existing popular varieties is estimated to be 1.39 Mt and Rs.2,432 crores per annum, respectively. Over the years, indents of breeder seed (BS) of NRRI varieties have increased considerably indicating growing popularities of NRRI varieties among the farmers in different states.

Comparative effectiveness of bladder-preserving tri-modality therapy versus radical cystectomy for muscle-invasive bladder cancer.

2018 ◽  
Vol 36 (6_suppl) ◽  
pp. 418-418 ◽  
Author(s):  
Trevor Joseph Royce ◽  
Adam S. Feldman ◽  
Matthew Mossanen ◽  
Joanna C. Yang ◽  
William U. Shipley ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Sensitivity Analyses ◽  
Invasive Bladder Cancer ◽  
Definitive Treatment ◽  
Muscle Invasive Bladder Cancer ◽  
Old Patients ◽  
Life Years ◽  
Incremental Gain ◽  
Muscle Invasive

418 Background: Radical cystectomy (RC) has historically been considered the standard of care for muscle invasive bladder cancer (MIBC). An alternative is tri-modality therapy (TMT), a bladder-sparing approach that often achieves preservation of the native bladder. There are limited randomized data comparing these guideline-recommended approaches but, in appropriately selected patients, both are thought to have similar survival outcomes with different morbidity profiles. Therefore this study compared the effectiveness of TMT and RC using decision-analytic modeling with the primary endpoint of quality-adjusted life years (QALYs). Methods: We developed a Markov model simulating the lifetime outcomes for 67-year-old patients after definitive treatment for American Joint Committee on Cancer clinical Stage T2-T4aN0M0 MIBC using two strategies: TMT or RC +/- neoadjuvant chemotherapy (NAC). Probabilities and utilities were extracted from the literature to determine the incremental effectiveness in QALYs. Sensitivity analyses were performed. Results: TMT was the most effective strategy with an incremental gain of 1.13 QALYs over RC (8.37 versus 7.24 QALYs, respectively; Table). One-way sensitivity analyses demonstrated the model was most sensitive to the quality of life (QoL) parameters (i.e. the utilities) for RC and TMT; TMT was more effective than RC irrespective of the RC utility (the 95% confidence interval of the RC parameter demonstrated an incremental gain with TMT of 0.01 to 4.77 QALYs). The model was relatively less sensitive to the probability of death for either strategy. Probabilistic sensitivity analysis demonstrated that TMT was more effective than RC for 75% of model iterations. Conclusions: Treatment of MIBC with organ-sparing TMT in appropriately-selected patients may result in a gain of over 1 QALY relative to RC. Further prospective investigation into the QoL implications of these treatment modalities is warranted. [Table: see text]

Sign in / Sign up

Export Citation Format

Share Document