A simple method for early age phenotype confirmation using toe tissue from a mouse model of MPS IIIA

2014 ◽  
Vol 28 (8) ◽  
pp. 933-938 ◽  
Author(s):  
Paul J. Trim ◽  
Adeline A. Lau ◽  
John J. Hopwood ◽  
Marten F. Snel
Keyword(s):  
Mouse Model ◽  
Early Age ◽  
Simple Method ◽  
Mps Iiia

Screening Youth Soccer Players by Means of Cognitive Function and Agility Testing

2021 ◽  
pp. 003151252110402
Author(s):  
Nicola Lovecchio ◽  
Gianluca Manes ◽  
Luca Filipas ◽  
Matteo Giuriato ◽  
Antonio La Torre ◽  
...  
Keyword(s):  
Motor Skills ◽  
Smartphone Application ◽  
Inhibitory Response ◽  
Soccer Players ◽  
Early Age ◽  
Unique Combination ◽  
Simple Method ◽  
Gross Motor Skills ◽  
Youth Soccer

Talent identification in sports is a heavily debated topic. Previous studies have separately explored either executive functions or gross motor skills to predict the success of top-level soccer players or, more generally, to characterize elite performance in soccer. However, at mid-childhood, the possibility to scope sport-specific requirements remains elusive. We aimed in this study to investigate a valid and simple method of testing for a unique combination of cognitive and speed abilities for identifying promising soccer players at mid-childhood. We measured cognitive functions by means of a Stroop smartphone application and agility with a T-Drill Ball-success test, in two groups of (a) elite- ( n = 31) and (b) low-division ( n = 37) Italian 7-year-old male soccer players. We administered the tests in a randomized order to both groups. We found better inhibitory control, cognitive flexibility and soccer-specific agility in high-division versus low-division players ( p < .001). Inhibitory response and agility were positively associated with the augmented quality of the performance from low-division players to high-division players ( r = .55; p = .0001). These results suggest that, even at an early age, cognitive control together with soccer-specific skills is associated with better performance.

scholarly journals Retinal Degeneration in MPS-IIIA Mouse Model

2020 ◽  
Vol 8 ◽  
Author(s):  
Daniela Intartaglia ◽  
Giuliana Giamundo ◽  
Elena Marrocco ◽  
Veronica Maffia ◽  
Francesco Giuseppe Salierno ◽  
...  
Keyword(s):  
Mouse Model ◽  
Retinal Degeneration ◽  
Mps Iiia

Functional correction and reversal of MPS IIIA in a mouse model by an intravenous hSGSH gene delivery using a self-complementary AAV9 vector

2014 ◽  
Vol 111 (2) ◽  
pp. S75 ◽  
Author(s):  
Douglas M. McCarty ◽  
Kimberly Zaraspe ◽  
Darren Murrey ◽  
Tierra Ware ◽  
Haiyan Fu
Keyword(s):  
Gene Delivery ◽  
Mouse Model ◽  
Functional Correction ◽  
Mps Iiia

scholarly journals Geopolymers Based on Mechanically Activated Fly Ash Blended with Dolomite

Minerals ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 700
Author(s):  
Alexander M. Kalinkin ◽  
Basya I. Gurevich ◽  
Elena V. Kalinkina ◽  
Mikhail V. Chislov ◽  
Irina A. Zvereva
Keyword(s):  
Compressive Strength ◽  
Fly Ash ◽  
Mechanical Activation ◽  
Raw Material ◽  
Early Age ◽  
X Ray Diffraction ◽  
Simple Method ◽  
X Ray ◽  
Alkaline Agent ◽  
Naoh Solution

This study reports the effect of natural dolomite addition to fly ash and the mechanical activation of this blend on the geopolymerization process. Dolomite was replaced with fly ash at 1, 3, 5, and 10 wt.%. Geopolymers were synthesized at ambient temperature using NaOH solution as an alkaline agent. The geopolymerization process, reactivity of the raw material, compressive strength, and microstructure were studied using X-ray diffraction, Fourier-transform infrared spectroscopy, thermogravimetry, and scanning electron microscopy. It was shown that blending fly ash with dolomite and mechanical activation improved the geopolymer strength, especially during the early age of curing. For geopolymers prepared using a 90% fly ash + 10% dolomite blend cured for 7 d, the strengths were 8.2-, 2.3-, and 1.4-fold higher than those for geopolymers prepared using 100% FA for 30 s, 180 s, and 400 s milling times, respectively. A simple method for evaluating the increments of mechanical activation, carbonate additives, and the synergistic effect in the increase in the compressive strength of the composite geopolymer is proposed.

scholarly journals Functional correction of CNS lesions in an MPS-IIIA mouse model by intracerebral AAV-mediated delivery of sulfamidase and SUMF1 genes

2007 ◽  
Vol 16 (22) ◽  
pp. 2693-2702 ◽  
Author(s):  
Alessandro Fraldi ◽  
Kim Hemsley ◽  
Allison Crawley ◽  
Alessia Lombardi ◽  
Adeline Lau ◽  
...  
Keyword(s):  
Mouse Model ◽  
Functional Correction ◽  
Mps Iiia ◽  
Cns Lesions

Neuroinflammatory and oxidative stress phenomena in MPS IIIA mouse model: The positive effect of long-term aspirin treatment

2011 ◽  
Vol 103 (1) ◽  
pp. 18-25 ◽  
Author(s):  
Audrey Arfi ◽  
Magali Richard ◽  
Christelle Gandolphe ◽  
Dominique Bonnefont-Rousselot ◽  
Patrice Thérond ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Mouse Model ◽  
Positive Effect ◽  
Mps Iiia ◽  
And Oxidative Stress

Improvement in behaviour after substrate deprivation therapy with rhodamine B in a mouse model of MPS IIIA

2007 ◽  
Vol 92 (1-2) ◽  
pp. 115-121 ◽  
Author(s):  
Ainslie L.K. Roberts ◽  
Matthew H. Rees ◽  
Sonja Klebe ◽  
Janice M. Fletcher ◽  
Sharon Byers
Keyword(s):  
Mouse Model ◽  
Rhodamine B ◽  
Substrate Deprivation ◽  
Mps Iiia

Correction of broad molecular impairments in a mouse model of MPS IIIA by systemic rAAVrh74-hSGSH gene delivery

2014 ◽  
Vol 111 (2) ◽  
pp. S44
Author(s):  
Haiyan Fu ◽  
F. Jason Duncan ◽  
Bartholomew Naughton ◽  
Kimberly Zaraspe ◽  
Darren Murrey ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Mouse Model ◽  
Mps Iiia
Sign in / Sign up

Export Citation Format

Share Document