The effects of grape seed extract ( Vitis vinifera ) supplement on inflammatory markers, neuropeptide Y, anthropometric measures, and appetite in obese or overweight individuals: A randomized clinical trial

2019 ◽  
Vol 34 (2) ◽  
pp. 379-387 ◽  
Author(s):  
Maryam Parandoosh ◽  
Reyhaneh Yousefi ◽  
Hoda Khorsandi ◽  
Omid Nikpayam ◽  
Atoosa Saidpour ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Vitis Vinifera ◽  
Neuropeptide Y ◽  
Randomized Clinical Trial ◽  
Inflammatory Markers ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Anthropometric Measures

scholarly journals Effect of grape seed extract on postprandial oxidative status and metabolic responses in men and women with the metabolic syndrome - randomized, cross-over, placebo-controlled study

2013 ◽  
Vol 2 (12) ◽  
pp. 508 ◽  
Author(s):  
Indika Edirisinghe ◽  
Jody Randolph ◽  
Mandeep Cheema ◽  
Ravi Tadapaneni ◽  
Eunyoung Park ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
Inflammatory Markers ◽  
Oxidized Ldl ◽  
Area Under The Curve ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Controlled Study ◽  
The Metabolic Syndrome

Objective: This investigation was undertaken to determine whether a grape seed extract (GSE) that is rich in mono-, oligo- and poly- meric polyphenols would modify postprandial oxidative stress and inflammation in individuals with the metabolic syndrome (MetS).Background: MetS is known to be associated with impaired glucose tolerance and poor glycemic control. Consumption of a meal high in readily available carbohydrates and fat causes postprandial increases in glycemia and lipidemia and markers of oxidative stress, inflammation and insulin resistance.Materials/methods: After an overnight fast, twelve subjects with MetS (5 men and 7 women) consumed a breakfast meal high in fat and carbohydrate in a cross-over design. A GSE (300 mg) or placebo capsule was administrated 1 hr before the meal (-1 hr). Changes in plasma insulin, glucose, oxidative stress and inflammatory markers were measured hourly for 6 hr. Results: Plasma hydrophilic oxygen radical absorbance capacity (ORAC) measured as the positive incremental area under the curve (-1 to 5 hr) was significantly increased when the meal was preceded by GSE compared with placebo (P<0.05). Meal-induced increases in oxidized LDL were attenuated with GSE (P<0.05). Plasma glucose concentrations (area under the curve from -1 to 5 hr) were also significantly lower when the meal was preceded by GSE (P<0.05) while the insulin concentrations remained unchanged (P>0.05). No changes in inflammatory markers were evident. Conclusion: These data suggest that GSE enhances postprandial plasma antioxidant status and reduces the glycemic response to a meal, high in fat and carbohydrate in subjects with the MetS. Key words: Polyphenols, Oxidative stress, Inflammation, ORAC, Oxidized LDL

scholarly journals Induction of apoptosis by grape seed extract (Vitis vinifera) in oral squamous cell carcinoma

2013 ◽  
Vol 13 (3) ◽  
pp. 186 ◽  
Author(s):  
Amirala Aghbali ◽  
Sepideh Vosough Hosseini ◽  
Abbas r Delaza ◽  
Nader Kalbasi Gharavi ◽  
Fatemeh Zare Shahneh ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Vitis Vinifera ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Induction Of Apoptosis

Vitis vinifera(grape) seed extract and resveratrol alleviate bisphenol-A-induced metabolic syndrome: Biochemical and molecular evidences

2019 ◽  
Vol 33 (3) ◽  
pp. 832-844 ◽  
Author(s):  
Maryam Rameshrad ◽  
Bibi Marjan Razavi ◽  
Mohsen Imenshahidi ◽  
Hossein Hosseinzadeh
Keyword(s):  
Metabolic Syndrome ◽  
Bisphenol A ◽  
Vitis Vinifera ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract
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