Therapeutic efficacy and safety of chamomile for state anxiety, generalized anxiety disorder, insomnia, and sleep quality: A systematic review and meta‐analysis of randomized trials and quasi‐randomized trials

2019 ◽  
Vol 33 (6) ◽  
pp. 1604-1615 ◽  
Author(s):  
Truong Hong Hieu ◽  
Mahmoud Dibas ◽  
Kadek Agus Surya Dila ◽  
Nourin Ali Sherif ◽  
Muhammad Usman Hashmi ◽  
...  
2017 ◽  
Vol 52 ◽  
pp. 25-33 ◽  
Author(s):  
Elon Gersh ◽  
David J. Hallford ◽  
Simon M. Rice ◽  
Nikolaos Kazantzis ◽  
Hannah Gersh ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Amir Adibi ◽  
Mohamad Golitaleb ◽  
Iman Farrahi-Ashtiani ◽  
Davoud Pirani ◽  
Kosar Yousefi ◽  
...  

Introduction: Health care workers, due to be involved in caring for COVID-19 patients may experience various psychological problems including anxiety disorders. This study aimed to investigate the prevalence of Generalized Anxiety Disorder (GAD) among health care workers during the COVID-19 pandemic by systematic review and meta-analysis.Methods: The PRISMA guideline was used for conducting this study. Related keywords were searched in credited resources including ISC, Magiran, PubMed, Scopus, Web of Science, Cochrane, ProQuest, Science Direct, Google Scholar, and Embase to find the articles published on the prevalence of GAD among health care workers during the COVID-19 pandemic from the first of January to the end of June 2020. Meta-analysis was conducted by the random effects model.Results: In this study, 553 articles were initially identified, from which 19 studies were finally included in the meta-analysis. The results showed that the prevalence of GAD in health care workers based on the GAD-7 and GAD-2 instruments were 32.04% (95% CI: 26.89–37.19, I2 = 98.2%, p < 0.001) and 22.62% (95% CI: 9.01–36.24, I2 = 97.7%, p < 0.001). The overall prevalence of GAD was obtained 30.5% (95% CI: 25.58–35.42, I2 = 98.4%, p < 0.001).Conclusion: This study showed a relatively high GAD prevalence, as one of the fundamental psychological problems, among health care workers during the COVID-19 pandemic. Therefore, health system managers should implement preventive strategies to protect health staff from contracting the virus and monitor them for psychological problems and provide them with supportive measures if necessary.


2006 ◽  
Vol 21 (7) ◽  
pp. 774-782 ◽  
Author(s):  
Jose Luis R. Martin ◽  
Maria Sainz-Pardo ◽  
Toshiaki A. Furukawa ◽  
Eva Martin-Sanchez ◽  
Teresa Seoane ◽  
...  

2015 ◽  
Vol 64 ◽  
pp. 88-98 ◽  
Author(s):  
Chi-Un Pae ◽  
Sheng-Min Wang ◽  
Changsu Han ◽  
Soo-Jung Lee ◽  
Ashwin A. Patkar ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Sheng Wang ◽  
Lin-lin Zhao ◽  
Xin-jian Qiu ◽  
Dong-sheng Wang ◽  
Tao Tang ◽  
...  

Background. The traditional Chinese medicine formula Jiu Wei Zhen Xin Granula (JWZXG) is prescribed to treat generalized anxiety disorder (GAD) in China. This study was to assess the efficacy and safety of JWZXG in patients with GAD. Method. Data were pooled from 14 randomized controlled trials involving the assessment of mean changes of Hamilton Anxiety Rating Scale (HAMA) total scores, response rates, adverse event rates, quality, publication bias, and risk of bias. Results. Pooled analysis showed no significant difference in response rate (risk ratio 1.01, 95% CI [0.93–1.08]; Z test = 0.17, P=0.86) and no significant difference between JWZXG group and azapirones group (RR 0.69, 95% CI [0.45, 1.06]; Z test = 1.69, P=0.09) in rate of adverse events. Though no difference exists between JWZXG group and azapirones group in HAMA total score from baseline, JWZXG group was inferior to selective serotonin reuptake inhibitors (SSRIs) group (WMD −0.93, 95% CI [−1.64, −0.23]; Z test = 2.6, P=0.009) which had more adverse events than JWZXG group (RR 0.64, 95% CI [0.46, 0.89]; Z test = 2.63, P=0.009). Conclusions. This meta-analysis preliminarily suggests that JWZXG is as effective as azapirones, though having the same possibility of suffering AEs. JWZXG was inferior to SSRIs but causes fewer AEs in the treatment of GAD.


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