Metabolomics Study of Type 2 Diabetes Mellitus and the AntiDiabetic Effect of Berberine in Zucker Diabetic Fatty Rats Using Uplc-ESI-Hdms

2016 ◽  
Vol 30 (5) ◽  
pp. 823-828 ◽  
Author(s):  
Yu Dong ◽  
Yi-Tao Chen ◽  
Yuan-Xiao Yang ◽  
Xiao-Jie Zhou ◽  
Shi-Jie Dai ◽  
...  
2020 ◽  
Vol 11 (5) ◽  
pp. 4339-4355 ◽  
Author(s):  
Xiaoyan Xia ◽  
Jing Xu ◽  
Xude Wang ◽  
Hua Wang ◽  
Zhenchuan Lin ◽  
...  

The use of plant-based beverages to interfere with the onset of diabetes may be a promising approach towards type 2 diabetes mellitus (T2DM).


2017 ◽  
Vol 2017 ◽  
pp. 1-14 ◽  
Author(s):  
Ceren Eyileten ◽  
Agnieszka Kaplon-Cieslicka ◽  
Dagmara Mirowska-Guzel ◽  
Lukasz Malek ◽  
Marek Postula

Brain-derived neurotrophic factor (BDNF) is a neurotrophin, which plays an important role in the central nervous system, and systemic or peripheral inflammatory conditions, such as acute coronary syndrome and type 2 diabetes mellitus (T2DM). BDNF is also expressed in several nonneuronal tissues, and platelets are the major source of peripheral BDNF. Here, we reviewed the potential role of BDNF in platelet reactivity in T2DM and its association with selected inflammatory and platelet activation mediators. Besides that, we focused on adipocytokines such as leptin, resistin, and adiponectin which are considered to take part in inflammation and both lipid and glucose metabolism in diabetic patients as previous studies showed the relation between adipocytokines and BDNF. We also reviewed the evidences of the antidiabetic effect of BDNF and the association with circulating inflammatory cytokines in T2DM.


2012 ◽  
Vol 2 (7) ◽  
pp. 268-269
Author(s):  
Dr. Poonam Sharma ◽  
◽  
Dr. Ajay Kr Sharma ◽  
K. N. Dwivedi K. N. Dwivedi

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