Effect of Astaxanthin Supplementation on Paraoxonase 1 Activities and Oxidative Stress Status in Young Soccer Players

2012 ◽  
pp. n/a-n/a ◽  
Author(s):  
Ivana Baralic ◽  
Brizita Djordjevic ◽  
Nenad Dikic ◽  
Jelena Kotur-Stevuljevic ◽  
Slavica Spasic ◽  
...  
2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Ivana Baralic ◽  
Marija Andjelkovic ◽  
Brizita Djordjevic ◽  
Nenad Dikic ◽  
Nenad Radivojevic ◽  
...  

The physiologic stress induced by physical activity is reflected in immune system perturbations, oxidative stress, muscle injury, and inflammation. We investigated the effect of astaxanthin (Asx) supplementation on salivary IgA (sIgA) and oxidative stress status in plasma, along with changes in biochemical parameters and total/differential white cell counts. Forty trained male soccer players were randomly assigned to Asx and placebo groups. Asx group was supplemented with 4 mg of Asx. Saliva and blood samples were collected at the baseline and after 90 days of supplementation in preexercise conditions. We observed a rise of sIgA levels at rest after 90 days of Asx supplementation, which was accompanied with a decrease in prooxidant-antioxidant balance. The plasma muscle enzymes levels were reduced significantly by Asx supplementation and by regular training. The increase in neutrophil count and hs-CRP level was found only in placebo group, indicating a significant blunting of the systemic inflammatory response in the subjects taking Asx. This study indicates that Asx supplementation improves sIgA response and attenuates muscle damage, thus preventing inflammation induced by rigorous physical training. Our findings also point that Asx could show significant physiologic modulation in individuals with mucosal immunity impairment or under conditions of increased oxidative stress and inflammation.


2016 ◽  
Vol 32 (3) ◽  
pp. 329-336 ◽  
Author(s):  
Abolfazl Nasiri ◽  
Nasrin Ziamajidi ◽  
Roghayeh Abbasalipourkabir ◽  
Mohammad Taghi Goodarzi ◽  
Massoud Saidijam ◽  
...  

2016 ◽  
Vol 46 (5) ◽  
pp. 418-424 ◽  
Author(s):  
Jasmina Ivanišević ◽  
Jelena Kotur-Stevuljević ◽  
Aleksandra Stefanović ◽  
Slavica Spasić ◽  
Violeta Vučinić Mihailović ◽  
...  

2009 ◽  
Vol 55 (4) ◽  
pp. 384-388 ◽  
Author(s):  
Yuri Karen Sinzato ◽  
Paula Helena Ortiz Lima ◽  
Kleber Eduardo de Campos ◽  
Ana Carolina Inhasz Kiss ◽  
Marilza Vieira Cunha Rudge ◽  
...  

2015 ◽  
Vol 54 (6) ◽  
pp. 1052-1064 ◽  
Author(s):  
Nergiz Hacer Turgut ◽  
Derya Guliz Mert ◽  
Haki Kara ◽  
Hatice Reyhan Egilmez ◽  
Emre Arslanbas ◽  
...  

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