Fertility control of rodent pests: a review of the inhibitory effects of plant extracts on ovarian function

2012 ◽  
Vol 69 (3) ◽  
pp. 342-354 ◽  
Author(s):  
Tung Thanh Tran ◽  
Lyn A Hinds
Keyword(s):  
Plant Extracts ◽  
Ovarian Function ◽  
Fertility Control ◽  
Inhibitory Effects

scholarly journals Endothelin (ET)-1 and ET-3 inhibit estrogen and cAMP production by rat granulosa cells in vitro

1998 ◽  
Vol 157 (2) ◽  
pp. 209-215 ◽  
Author(s):  
AE Calogero ◽  
N Burrello ◽  
AM Ossino
Keyword(s):  
Granulosa Cells ◽  
Ovarian Function ◽  
Biological Effects ◽  
Female Rats ◽  
Dependent Manner ◽  
Camp Production ◽  
Inhibitory Effects ◽  
Ovarian Steroidogenesis ◽  
Estrogen Production ◽  
Etb Receptor

Endothelin (ET)-1 and ET-3, two peptides with a potent vasoconstrictive property, produce a variety of biological effects in different tissues by acting through two different receptors, the ET-1 selective ET(A) receptor and the non-selective ETB receptor. An increasing body of literature suggests that ET-1 acts as a paracrine/autocrine regulator of ovarian function. Indeed, ETB receptors have been identified in rat granulosa cells and ET-1 is a potent inhibitor of progesterone production. In contrast, inconsistent data have been reported about the role of ET-1 on estrogen production and the effects of ET-3 are not known. Therefore, the present study was undertaken to evaluate the effects of ET-1 and ET-3 on estrogen and cAMP production, and the receptor type involved. Given that prostanoids modulate ovarian steroidogenesis and that many actions of ETs are mediated by these compounds, we also evaluated whether the effects of ETs on estrogen and cAMP production might be prostanoid-mediated. ET-1, ET-3, and safarotoxin-S6c (SFX-S6c), a selective ETB receptor agonist, inhibited basal estrogen production by granulosa cells obtained from immature, estrogen-primed female rats, in a concentration-dependent manner. All three peptides were also capable of inhibiting the production of estrogen stimulated by a half-maximal (1 mIU/ml) and a maximally stimulatory (3 mIU/ml) concentration of FSH, ET-1 and ET-3 dose-dependently suppressed basal and FSH (1 mIU/ml)-stimulated cAMP production. ET-3 and SFX-S6c were significantly more potent than ET-1 in suppressing estrogen production, suggesting that this effect was not mediated by the ET(A) receptor. Indeed, BQ-123, a selective ET(A) receptor antagonist, did not influence the inhibitory effects of ET-1 and ET-3 on basal and FSH-stimulated estrogen release. To determine a possible involvement of prostanoids, we evaluated the effects of maximally effective concentrations of ET-1 and ET-3 on estrogen and cAMP production in the presence of indomethacin, a prostanoid synthesis inhibitor. This compound did not have any effect on the suppressive effects of ETs on basal or FSH (1 mIU/ml)-stimulated estrogen or cAMP production. In conclusion, ET-1 and ET-3 were able to inhibit estrogen and cAMP production by rat granulosa cells, indicating that the inhibitory effects of ETs on ovarian steroidogenesis are not limited to progesterone biosynthesis. This effect does not appear to be mediated by prostanoids or by the classical ET(A) and ETB receptors, at least under these experimental conditions.

Study of monoamine oxidase inhibitory effects of seven Iranian medicinal plant extracts

2021 ◽  
Vol 10 (2) ◽  
pp. 187
Author(s):  
Maliheh Soodi ◽  
Mohsen Shamsi ◽  
Homa Hajimehdipoor ◽  
Alireza Ghazanfari
Keyword(s):  
Medicinal Plant ◽  
Monoamine Oxidase ◽  
Plant Extracts ◽  
Inhibitory Effects ◽  
Medicinal Plant Extracts

Inhibitory effects of indonesian plant extracts on reverse transcriptase of an RNA Tumour Virus (I)

1992 ◽  
Vol 6 (5) ◽  
pp. 241-244 ◽  
Author(s):  
I. T. Kusumoto ◽  
I. Shimada ◽  
N. Kakiuchi ◽  
M. Hattori ◽  
T. Namba ◽  
...  
Keyword(s):  
Reverse Transcriptase ◽  
Plant Extracts ◽  
Inhibitory Effects

Inhibitory effects of plant extracts on adjuvant-induced arthritis

1997 ◽  
Vol 20 (4) ◽  
pp. 313-317 ◽  
Author(s):  
Sung Yong Kim ◽  
Kun Ho Son ◽  
Hyun Wook Chang ◽  
Sam Sik Kang ◽  
Hyun Pyo Kim
Keyword(s):  
Plant Extracts ◽  
Inhibitory Effects ◽  
Adjuvant Induced Arthritis

scholarly journals The inhibitory effect of some plant extracts in the laboratory growth characteristics of tomato seedlings

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Ahmed Amir Murad AL Mandlawy ◽  
Raghda Safaa Al-ddin Al –Khalidi
Keyword(s):  
Plant Extracts ◽  
Inhibitory Effect ◽  
Growth Characteristics ◽  
Inhibitory Effects ◽  
Tomato Seedlings ◽  
Tomato Seeds ◽  
Johnson Grass ◽  
Randomized Design ◽  
Completely Randomized Design ◽  
Landscape Gardening

"An Laboratory experiment was carried out in the Department of Horticulture and Landscape Gardening - Faculty of Agriculture - Diyala University for the spring season 2017 in order to study the inhibitory effects of some plant extracts on the laboratory growth characteristics of the Tomato seeds, using Petri dishes designed in Completely Randomized Design ( CRD) in three replicates to study the effect of three different concentrations (zero , 50% and 100%) of water extracts of onion, Blady grass, Nut grass and Johnson grass in the percentage of seed germination of Tomato seeds and the growth rate and some other growth characteristics of theTomato seeds. The experimental results can be summarized as follows, Plant extracts affected For each of the onion, Blady grass, Nut grass and Johnson grass and the concentrations used, and interferences between them, have a significant effect in all studied traits of Tomato seeds the treatment resulted in the plant extract of Nut grass and Johnson grass On the occurrence of high and clear inhibitions in all the studied traits of the tomato seeds, while the other plant extracts varied with the degree of inhibition.

scholarly journals An evaluation of the RNase H inhibitory effects of Vietnamese medicinal plant extracts and natural compounds

2011 ◽  
Vol 49 (10) ◽  
pp. 1046-1051 ◽  
Author(s):  
Bui Huu Tai ◽  
Nguyen Duy Nhut ◽  
Nguyen Xuan Nhiem ◽  
Tran Hong Quang ◽  
Nguyen Thi Thanh Ngan ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Plant Extracts ◽  
Natural Compounds ◽  
Rnase H ◽  
Inhibitory Effects ◽  
Medicinal Plant Extracts

Selective LXRα inhibitory effects observed in plant extracts of MEH184 (Parthenocissua tricuspidata) and MEH185 (Euscaphis japonica)

2006 ◽  
Vol 349 (2) ◽  
pp. 513-518 ◽  
Author(s):  
Kang Ho Kim ◽  
Seung Hyun Choi ◽  
Thomas S. Lee ◽  
Won Keun Oh ◽  
Dong Sun Kim ◽  
...  
Keyword(s):  
Plant Extracts ◽  
Inhibitory Effects

Inhibitory effects of Sudanese medicinal plant extracts on hepatitis C virus (HCV) protease

2000 ◽  
Vol 14 (7) ◽  
pp. 510-516 ◽  
Author(s):  
Ghazi Hussein ◽  
Hirotsugu Miyashiro ◽  
Norio Nakamura ◽  
Masao Hattori ◽  
Nobuko Kakiuchi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Medicinal Plant ◽  
Plant Extracts ◽  
Inhibitory Effects ◽  
Medicinal Plant Extracts ◽  
Hcv Protease
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