scholarly journals Comparison between esomeprazole 20 mg Vs 40 mg as stress ulcer prophylaxis (SUP) in critically ill patients: A retrospective cohort study

2020 ◽  
Vol 8 (4) ◽  
Author(s):  
Khalid Al Sulaiman ◽  
Kholoud Al Aamer ◽  
Alaa Al Harthi ◽  
Saud Jaser ◽  
Abdulrahman Al Anazi ◽  
...  
Keyword(s):  
Cohort Study ◽  
Critically Ill ◽  
Retrospective Cohort Study ◽  
Critically Ill Patients ◽  
Retrospective Cohort ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Ulcer Prophylaxis ◽  
As Stress

scholarly journals Proton pump inhibitors versus histamine-2 receptor blockers for stress ulcer prophylaxis in patients with sepsis: a retrospective cohort study

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110251
Author(s):  
Minqiang Huang ◽  
Ming Han ◽  
Wei Han ◽  
Lei Kuang
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Hospital Mortality ◽  
Critically Ill ◽  
Proton Pump ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Stress Ulcer ◽  
Increased Risk ◽  
Ulcer Prophylaxis

Objective We aimed to compare the efficacy and risks of proton pump inhibitor (PPI) versus histamine-2 receptor blocker (H2B) use for stress ulcer prophylaxis (SUP) in critically ill patients with sepsis and risk factors for gastrointestinal bleeding (GIB). Methods In this retrospective cohort study, we used the Medical Information Mart for Intensive Care III Clinical Database to identify critically ill adult patients with sepsis who had at least one risk factor for GIB and received either an H2B or PPI for ≥48 hours. Propensity score matching (PSM) was conducted to balance baseline characteristics. The primary outcome was in-hospital mortality. Results After 1:1 PSM, 1056 patients were included in the H2B and PPI groups. The PPI group had higher in-hospital mortality (23.8% vs. 17.5%), GIB (8.9% vs. 1.6%), and pneumonia (49.6% vs. 41.6%) rates than the H2B group. After adjusting for risk factors of GIB and pneumonia, PPI use was associated with a 1.28-times increased risk of in-hospital mortality, 5.89-times increased risk of GIB, and 1.32-times increased risk of pneumonia. Conclusions Among critically ill adult patients with sepsis at risk for GIB, SUP with PPIs was associated with higher in-hospital mortality and higher risk of GIB and pneumonia than H2Bs.

Enteral nutrition as stress ulcer prophylaxis in critically ill patients: A randomized controlled exploratory study

2018 ◽  
Vol 43 ◽  
pp. 108-113 ◽  
Author(s):  
Karim El-Kersh ◽  
Bilal Jalil ◽  
Stephen A. McClave ◽  
Rodrigo Cavallazzi ◽  
Juan Guardiola ◽  
...  
Keyword(s):  
Enteral Nutrition ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Exploratory Study ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Randomized Controlled ◽  
Ulcer Prophylaxis ◽  
As Stress

scholarly journals Adherence to a stress ulcer prophylaxis protocol by critically ill patients: a prospective cohort study

2020 ◽  
Vol 32 (1) ◽  
Author(s):  
Yuri de Albuquerque Pessoa dos Santos ◽  
Mauricio Staib Younes-Ibrahim ◽  
Lucas Lonardoni Crozatti ◽  
Dante Raglione ◽  
Luis Carlos Maia Cardozo Junior ◽  
...  
Keyword(s):  
Cohort Study ◽  
Critically Ill ◽  
Prospective Cohort Study ◽  
Critically Ill Patients ◽  
Prospective Cohort ◽  
Stress Ulcer ◽  
Stress Ulcer Prophylaxis ◽  
Ulcer Prophylaxis

scholarly journals Predictors of early postdischarge mortality in critically ill patients: A retrospective cohort study from the California Intensive Care Outcomes project

2011 ◽  
Vol 26 (1) ◽  
pp. 65-75 ◽  
Author(s):  
Eduard E. Vasilevskis ◽  
Michael W. Kuzniewicz ◽  
Brian A. Cason ◽  
Rondall K. Lane ◽  
Mitzi L. Dean ◽  
...  
Keyword(s):  
Cohort Study ◽  
Intensive Care ◽  
Critically Ill ◽  
Retrospective Cohort Study ◽  
Critically Ill Patients ◽  
Retrospective Cohort ◽  
Care Outcomes
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