scholarly journals Nerve growth factor inhibitor with novel-binding domain demonstrates nanomolar efficacy in both cell-based and cell-free assay systems

2017 ◽  
Vol 5 (5) ◽  
pp. e00339 ◽  
Author(s):  
Allison E. Kennedy ◽  
Corey A. Laamanen ◽  
Mitchell S. Ross ◽  
Rahul Vohra ◽  
Douglas R. Boreham ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Binding Domain ◽  
Nerve Growth ◽  
Factor Inhibitor

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

Nature ◽  
10.1038/43705 ◽  
1999 ◽  
Vol 401 (6749) ◽  
pp. 184-188 ◽  
Author(s):  
Christian Wiesmann ◽  
Mark H. Ultsch ◽  
Steven H. Bass ◽  
Abraham M. de Vos
Keyword(s):  
Crystal Structure ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Ligand Binding ◽  
Binding Domain ◽  
Ligand Binding Domain ◽  
Trka Receptor ◽  
Nerve Growth

Induction of a Nerve Growth Factor-Sensitive Kinase that Phosphorylates the DNA-Binding Domain of the Orphan Nuclear Receptor NGFI-B

2002 ◽  
Vol 65 (4) ◽  
pp. 1780-1788 ◽  
Author(s):  
Yoko Hirata ◽  
Michael Whalin ◽  
David D. Ginty ◽  
Jun Xing ◽  
Michael E. Greenberg ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Dna Binding ◽  
Nuclear Receptor ◽  
Binding Domain ◽  
Dna Binding Domain ◽  
Orphan Nuclear Receptor ◽  
Nerve Growth

Nerve safety of tanezumab, a nerve growth factor inhibitor for pain treatment

2014 ◽  
Vol 345 (1-2) ◽  
pp. 139-147 ◽  
Author(s):  
Mark T. Brown ◽  
David N. Herrmann ◽  
Mark Goldstein ◽  
Aimee M. Burr ◽  
Michael D. Smith ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Pain Treatment ◽  
Nerve Growth ◽  
Factor Inhibitor
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