A randomized, crossover pharmacodynamic study of immediate‐release omeprazole/sodium bicarbonate and delayed‐release lansoprazole in healthy adult volunteers

Vijayalakshmi S. Pratha; Thomas McGraw; William Tobin

doi:10.1002/prp2.238

A randomized, crossover pharmacodynamic study of immediate‐release omeprazole/sodium bicarbonate and delayed‐release lansoprazole in healthy adult volunteers

Pharmacology Research & Perspectives ◽

10.1002/prp2.238 ◽

2016 ◽

Vol 4 (3) ◽

Author(s):

Vijayalakshmi S. Pratha ◽

Thomas McGraw ◽

William Tobin

Keyword(s):

Sodium Bicarbonate ◽

Healthy Adult ◽

Immediate Release ◽

Delayed Release ◽

Pharmacodynamic Study ◽

Adult Volunteers

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First‐in‐Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.700 ◽

2019 ◽

Vol 9 (1) ◽

pp. 115-129 ◽

Cited By ~ 10

Author(s):

Jonathan C. Fox ◽

Jennifer L. Hellawell ◽

Satish Rao ◽

Terry O'Reilly ◽

Rick Lumpkin ◽

...

Keyword(s):

Healthy Adult ◽

Phase 1 ◽

Human Study ◽

Transthyretin Amyloidosis ◽

Pharmacodynamic Study ◽

Adult Volunteers

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The safety, pharmacodynamics, and pharmacokinetics of immediate-release formulation containing esomeprazole 20 mg/sodium bicarbonate 800 mg in healthy adult male

Drug Design Development and Therapy ◽

10.2147/dddt.s212491 ◽

2019 ◽

Vol Volume 13 ◽

pp. 3151-3159

Author(s):

Dasohm Kim ◽

Min Soo Park ◽

Byung Won Yoo ◽

Taegon Hong ◽

Shin Jung Park ◽

...

Keyword(s):

Sodium Bicarbonate ◽

Adult Male ◽

Healthy Adult ◽

Immediate Release ◽

Release Formulation ◽

Healthy Adult Male

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Retrospective Assessment of Immediate-Release Omeprazole/Sodium Bicarbonate in Improvement of GERD Symptoms in Patients Who Failed Delayed-Release Proton Pump Inhibitors

The American Journal of Gastroenterology ◽

10.14309/00000434-200910003-00082 ◽

2009 ◽

Vol 104 ◽

pp. S33-S34

Author(s):

John Jolley

Keyword(s):

Sodium Bicarbonate ◽

Proton Pump Inhibitors ◽

Proton Pump ◽

Immediate Release ◽

Delayed Release ◽

Retrospective Assessment ◽

Gerd Symptoms

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Similar pharmacokinetics of three dosing regimens comprising two oral delayed‐release mesalamine formulations in healthy adult volunteers: Randomised, open‐label, parallel‐group study

British Journal of Clinical Pharmacology ◽

10.1111/bcp.14479 ◽

2020 ◽

Author(s):

Niels Vande Casteele ◽

Abhijeet Jakate ◽

Brian McNamee ◽

William J. Sandborn

Keyword(s):

Healthy Adult ◽

Open Label ◽

Delayed Release ◽

Parallel Group Study ◽

Parallel Group ◽

Dosing Regimens ◽

Adult Volunteers

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Steady-State Bioavailability of Extended-Release Methylphenidate (MPH-MLR) Capsule vs. Immediate-Release Methylphenidate Tablets in Healthy Adult Volunteers

Clinical Drug Investigation ◽

10.1007/s40261-014-0234-x ◽

2014 ◽

Vol 34 (11) ◽

pp. 795-805 ◽

Cited By ~ 11

Author(s):

Akwete Adjei ◽

Robert J. Kupper ◽

Nathan S. Teuscher ◽

Sharon Wigal ◽

Floyd Sallee ◽

...

Keyword(s):

Steady State ◽

Extended Release ◽

Healthy Adult ◽

Immediate Release ◽

Adult Volunteers

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Relative bioavailability of griseofulvin lyophilized dry emulsion tablet vs. immediate release tablet: A single-dose, randomized, open-label, six-period, crossover study in healthy adult volunteers in the fasted and fed states

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2008.07.002 ◽

2008 ◽

Vol 35 (3) ◽

pp. 219-225 ◽

Cited By ~ 16

Author(s):

Iman Saad Ahmed ◽

Mona Hassan Aboul-Einien ◽

Osama Hussein Mohamed ◽

Samar Farghali Farid

Keyword(s):

Single Dose ◽

Crossover Study ◽

Healthy Adult ◽

Immediate Release ◽

Relative Bioavailability ◽

Open Label ◽

Dry Emulsion ◽

Adult Volunteers ◽

Release Tablet

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Acid Inhibitory Effect of a Combination of Omeprazole and Sodium Bicarbonate (CDFR0209) Compared With Delayed-Release Omeprazole 40 mg Alone in Healthy Adult Male Subjects

Clinical Pharmacology in Drug Development ◽

10.1002/cpdd.331 ◽

2017 ◽

Vol 7 (1) ◽

pp. 53-58

Author(s):

Kyu-Nam Kim ◽

Sung-Won Yang ◽

Hyunil Kim ◽

Seong Shin Kwak ◽

Young-Sang Kim ◽

...

Keyword(s):

Sodium Bicarbonate ◽

Adult Male ◽

Healthy Adult ◽

Inhibitory Effect ◽

Delayed Release ◽

Healthy Adult Male ◽

Male Subjects

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Bioavailability of once-daily venlafaxine extended release compared with the immediate-release formulation in healthy adult volunteers

Current Therapeutic Research ◽

10.1016/s0011-393x(97)80041-0 ◽

1997 ◽

Vol 58 (8) ◽

pp. 492-503 ◽

Cited By ~ 12

Author(s):

Steven M. Troy ◽

Clifford Dilea ◽

Patrick T. Martin ◽

Amy S. Rosen ◽

Richard J. Fruncillo ◽

...

Keyword(s):

Extended Release ◽

Healthy Adult ◽

Immediate Release ◽

Release Formulation ◽

Once Daily ◽

Adult Volunteers

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Single-Dose Pharmacokinetics of Methylphenidate Extended-Release Multiple Layer Beads Administered as Intact Capsule or Sprinkles Versus Methylphenidate Immediate-Release Tablets (Ritalin®) in Healthy Adult Volunteers

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2013.0135 ◽

2014 ◽

Vol 24 (10) ◽

pp. 570-578 ◽

Cited By ~ 18

Author(s):

Akwete Adjei ◽

Nathan S. Teuscher ◽

Robert J. Kupper ◽

Wei-Wei Chang ◽

Laurence Greenhill ◽

...

Keyword(s):

Single Dose ◽

Extended Release ◽

Healthy Adult ◽

Immediate Release ◽

Multiple Layer ◽

Adult Volunteers

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Interleukin 10-induced thrombocytopenia in normal healthy adult volunteers: evidence for decreased platelet production

British Journal of Haematology ◽

10.1046/j.1365-2141.2000.02314.x ◽

2000 ◽

Vol 111 (1) ◽

pp. 104-111 ◽

Cited By ~ 23

Author(s):

Jeffrey A. Sosman ◽

Amit Verma ◽

Steven Moss ◽

Patricia Sorokin ◽

Michael Blend ◽

...

Keyword(s):

Healthy Adult ◽

Interleukin 10 ◽

Platelet Production ◽

Adult Volunteers

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