Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors

2006 ◽  
Vol 66 (3) ◽  
pp. 538-546 ◽  
Author(s):  
Artem G. Evdokimov ◽  
Matthew Pokross ◽  
Richard L. Walter ◽  
Marlene Mekel ◽  
Bobby L. Barnett ◽  
...  
Keyword(s):  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors

Ionic Immobilization, Diversification, and Release: Application to the Generation of a Library of Methionine Aminopeptidase Inhibitors

2008 ◽  
Vol 10 (2) ◽  
pp. 185-194 ◽  
Author(s):  
Punitha Vedantham ◽  
Jennifer M. Guerra ◽  
Frank Schoenen ◽  
Min Huang ◽  
Parul J. Gor ◽  
...  
Keyword(s):  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors

Investigations and design of pyridine-2-carboxylic acid thiazol-2-ylamide analogs as methionine aminopeptidase inhibitors using 3D-QSAR and molecular docking

2014 ◽  
Vol 23 (8) ◽  
pp. 3861-3875 ◽  
Author(s):  
Potshangbam Angamba Meetei ◽  
Alexander S. Hauser ◽  
Prathigadapa S. Raju ◽  
R. S. Rathore ◽  
N. Prakash Prabhu ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Carboxylic Acid ◽  
3D Qsar ◽  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors

Methionine Aminopeptidase Inhibitors in Mammalian Cells

2020 ◽  
Vol 34 (S1) ◽  
pp. 1-1
Author(s):  
Natalia Condic ◽  
Cassandra Ramtahal ◽  
Jamila Boukari ◽  
Alex Croes ◽  
Calvin Nguyen ◽  
...  
Keyword(s):  
Mammalian Cells ◽  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors

Peptidyl hydroxamic acids as methionine aminopeptidase inhibitors

2004 ◽  
Vol 14 (1) ◽  
pp. 77-79 ◽  
Author(s):  
Xubo Hu ◽  
Jinge Zhu ◽  
Sumant Srivathsan ◽  
Dehua Pei
Keyword(s):  
Hydroxamic Acids ◽  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors

Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors

2010 ◽  
Vol 20 (14) ◽  
pp. 4038-4044 ◽  
Author(s):  
Markus A. Altmeyer ◽  
Aline Marschner ◽  
Rolf Schiffmann ◽  
Christian D. Klein
Keyword(s):  
Methionine Aminopeptidase ◽  
Subtype Selectivity ◽  
Aminopeptidase Inhibitors

scholarly journals Potential Cytotoxicity of Methionine Aminopeptidase Inhibitors on Mammalian Cells

2021 ◽  
Vol 35 (S1) ◽  
Author(s):  
Alex Croes ◽  
Jamila Boukari ◽  
Melissa Alvarez ◽  
Jennifer Clymer ◽  
Robert Flores ◽  
...  
Keyword(s):  
Mammalian Cells ◽  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors

Studies Towards the Synthesis of Methionine Aminopeptidase Inhibitors: Diversification Utilizing a ROMP-Derived Coupling Reagent

2008 ◽  
Vol 10 (2) ◽  
pp. 195-203 ◽  
Author(s):  
Punitha Vedantham ◽  
Mianji Zhang ◽  
Parul J. Gor ◽  
Min Huang ◽  
Gunda I. Georg ◽  
...  
Keyword(s):  
Methionine Aminopeptidase ◽  
Coupling Reagent ◽  
Aminopeptidase Inhibitors

Diketo acids and their amino acid/dipeptidic analogues as promising scaffolds for the development of bacterial methionine aminopeptidase inhibitors

RSC Advances ◽  
2015 ◽  
Vol 5 (43) ◽  
pp. 34173-34183 ◽  
Author(s):  
Mir Mohammad Masood ◽  
Vijay K. Pillalamarri ◽  
Mohammad Irfan ◽  
Babita Aneja ◽  
Mohamad Aman Jairajpuri ◽  
...  
Keyword(s):  
Amino Acid ◽  
Enzymatic Assay ◽  
Methionine Aminopeptidase ◽  
Diketo Acids ◽  
Aminopeptidase Inhibitors

Diketo acids and their peptidic analogues were designed and synthesised as bacterial MetAP inhibitors. In the enzymatic assay, the representative compound 5e showed excellent inhibition of bacterial MetAPs with no cytotoxicity.

Peptidyl Hydroxamic Acids as Methionine Aminopeptidase Inhibitors.

ChemInform ◽  
2004 ◽  
Vol 35 (18) ◽  
Author(s):  
Xubo Hu ◽  
Jinge Zhu ◽  
Sumant Srivathsan ◽  
Dehua Pei
Keyword(s):  
Hydroxamic Acids ◽  
Methionine Aminopeptidase ◽  
Aminopeptidase Inhibitors
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