EGFR-SGLT1 interaction does not respond to EGFR modulators, but inhibition of SGLT1 sensitizes prostate cancer cells to EGFR tyrosine kinase inhibitors

The Prostate ◽  
2013 ◽  
Vol 73 (13) ◽  
pp. 1453-1461 ◽  
Author(s):  
Jiangong Ren ◽  
Lakshmi R. Bollu ◽  
Fei Su ◽  
Guang Gao ◽  
Lei Xu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tyrosine Kinase ◽  
Cancer Cells ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Prostate Cancer Cells ◽  
Egfr Tyrosine Kinase ◽  
Egfr Tyrosine Kinase Inhibitors

Akt down-modulation induces apoptosis of human prostate cancer cells and synergizes with EGFR tyrosine kinase inhibitors

The Prostate ◽  
2008 ◽  
Vol 68 (9) ◽  
pp. 965-974 ◽  
Author(s):  
Claudio Festuccia ◽  
Giovanni Luca Gravina ◽  
Paola Muzi ◽  
Danilo Millimaggi ◽  
Vincenza Dolo ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tyrosine Kinase ◽  
Cancer Cells ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Prostate Cancer Cells ◽  
Egfr Tyrosine Kinase ◽  
Egfr Tyrosine Kinase Inhibitors

scholarly journals EGFR tyrosine kinase inhibitors promote pro-caspase-8 dimerization that sensitizes cancer cells to DNA-damaging therapy

Oncotarget ◽  
2015 ◽  
Vol 6 (19) ◽  
pp. 17491-17500 ◽  
Author(s):  
Yun-Tian Li ◽  
Xiao-Jun Qian ◽  
Yan Yu ◽  
Zhen-Hua Li ◽  
Rui-Yan Wu ◽  
...  
Keyword(s):  
Tyrosine Kinase ◽  
Cancer Cells ◽  
Tyrosine Kinase Inhibitors ◽  
Kinase Inhibitors ◽  
Caspase 8 ◽  
Egfr Tyrosine Kinase ◽  
Egfr Tyrosine Kinase Inhibitors
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