Predictors of response to medications for asthma in pediatric patients: A systematic review of the literature

2020 ◽  
Vol 55 (6) ◽  
pp. 1320-1331
Author(s):  
Carlos E. Rodriguez‐Martinez ◽  
Monica P. Sossa‐Briceño ◽  
Jose A. Castro‐Rodriguez
2018 ◽  
Vol 71 (suppl 6) ◽  
pp. 2818-2823
Author(s):  
Noélia Souza Santos Araújo ◽  
Rogério Rodrigues Floriano Pereira ◽  
Dayana Fram ◽  
Paula Hino ◽  
Maria Cristina Barbosa Longo ◽  
...  

ABSTRACT Objective: To identify in the literature studies that evaluate the quality of life in pediatric patients with kidney transplant through use of specific, validated instruments in Pediatrics. Method: Systematic review of the literature with searches conducted in the following databases: Medline, PubMed, LILACS, CINAHL, SciELO and Cochrane Library. Main keywords: Quality of life, Kidney transplantation and Pediatrics. Results: A total of 366 studies were selected and eight observational studies were included that evaluated the quality of life of children with kidney transplant by means of evaluation instruments of quality of life. Conclusion: The quality of life of children with kidney transplant is inferior compared to healthy children. The post-transplant period presents better results compared to pre-transplant children. The identification of mental, physical and social conditions related to the quality of life of this population allows for better planning the assistance provided to them.


2017 ◽  
Vol 19 (2) ◽  
pp. 149-156 ◽  
Author(s):  
Joaquin E. Jimenez ◽  
Zachary C. Gersey ◽  
Jason Wagner ◽  
Brian Snelling ◽  
Sudheer Ambekar ◽  
...  

OBJECTIVE Pediatric patients are at risk for the recurrence of brain arteriovenous malformation (AVM) after resection. While there is general consensus on the importance of follow-up after surgical removal of an AVM, there is a lack of consistency in the duration of that follow-up. The object of this systematic review was to examine the role of follow-up imaging in detecting AVM recurrence early and preventing AVM rupture. METHODS This systematic review was performed using articles obtained through a search of the literature contained in the MeSH database, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. RESULTS Search results revealed 1052 articles, 13 of which described 31 cases of AVM recurrence meeting the criteria for inclusion in this study. Detection of AVM occurred significantly earlier (mean ± SD, 3.56 ± 3.67 years) in patients with follow-up imaging than in those without (mean 8.86 ± 5.61 years; p = 0.0169). While 13.34% of patients who underwent follow-up imaging presented with rupture of a recurrent AVM, 57.14% of those without follow-up imaging presented with a ruptured recurrence (p = 0.0377). CONCLUSIONS Follow-up imaging has an integral role after AVM resection and is sometimes not performed for a sufficient period, leading to delayed detection of recurrence and an increased likelihood of a ruptured recurrent AVM.


2018 ◽  
Vol 31 (6) ◽  
pp. 283-302 ◽  
Author(s):  
Caroline Masse-Sibille ◽  
Bennabi Djamila ◽  
Giustiniani Julie ◽  
Haffen Emmanuel ◽  
Vandel Pierre ◽  
...  

Background: Geriatric depression is a heterogeneous disorder that increases morbidity and mortality in a population that is already vulnerable. Predicting response and remission to antidepressants could help clinicians to optimize the management of antidepressants and reduce the consequences of depression. Method: The aim of this article is to present results of a systematic review of the literature on predictive factors related to antidepressant response and remission in older adults with depression. Main Findings: We identified sociodemographic, clinical, neuropsychological, neuroimaging, and genetic factors that could be potential predictors of outcomes. Inconsistent findings and methodological differences among studies, however, limit the generalizability and application of these predictors in clinical practice. The results of our review confirm that geriatric depression includes many subgroups of patients with particular endophenotypes that may influence the course of depression. Conclusion: Further studies are needed to characterize depression subgroups in order to better understand the pathophysiology of late life depression and to find specific predictors for each group of patients.


2019 ◽  
Vol 34 (4) ◽  
pp. 189-198 ◽  
Author(s):  
Alysa Almojuela ◽  
Mohammed Hasen ◽  
Frederick A. Zeiler

The Full Outline of UnResponsiveness (FOUR) score is a neurologic assessment score. Its benefit over pre-existing scores is its evaluation of brainstem reflexes and respiratory pattern. Our goal was to perform a scoping systematic review of the literature on the application of the FOUR score within pediatric patients. Six databases were searched and 2 reviewers independently screened the results. The initial search yielded 1709 citations; ultimately, 6 studies composed of 571 pediatric patients were used. Four studies examined interobserver reliability of the FOUR score and found it to be good to excellent. All 6 studies demonstrated equivalency of the FOUR score and Glasgow Coma Scale (GCS) in predicting outcome. The existing literature suggests the FOUR score is equivalent to GCS in outcome prediction in pediatric patients; its true superiority over the GCS has not yet been established. It displays good to excellent inter-rater reliability among physicians and nurses.


2019 ◽  
Vol 16 (2) ◽  
pp. 49-55
Author(s):  
D. G. Naumov ◽  
E. A. Speranskaya ◽  
M. A. Mushkin ◽  
D. B. Malamashin ◽  
A. Yu. Mushkin

Publications on aneurysmal bone cysts of the spine in children for the last 20 years were systematized taking into account different treatment approaches. The results of radiation therapy, local puncture interventions, surgical removal of the tumor, selective embolization, and of their combinations were reviewed based on the data of 19 publications representing 165 pediatric patients.


2016 ◽  
Vol 84 (1) ◽  
pp. 55-60 ◽  
Author(s):  
Marco Oderda ◽  
Giorgio Calleris ◽  
Marco Allasia ◽  
Ettore Dalmasso ◽  
Marco Falcone ◽  
...  

Objective The aim of this study was to describe the technical aspects of a robotic pyeloplasty in pediatric patients with uretero-pelvic junction obstruction (UPJO) in horseshoe kidney (HSK) through the report of our recent case, and to outline the state of the art of minimally invasive pyeloplasty (MIP) with a systematic review of the literature. Methods We describe all the steps of our surgery performed on an 11-year-old patient with left UPJO in HSK in detail. All the anatomic landmarks are clearly showed, with particular attention to trocar placement in a pediatric patient. A systematic review of the literature on the outcomes of MIP in HSK patients has been performed, including 16 articles. Results Our surgery was successful following a standardized approach. However, we recorded a rare complication, the herniation of a small portion of omentum through the 8 - mm defect used for the caudal robotic port. The evidence synthesis shows excellent postoperative outcomes for both laparoscopic and robot-assisted laparoscopic pyeloplasties in HSK patients. Probably, MIP should be preferred to the traditional open approach in these patients, when feasible. Conclusions Transperitoneal robotic pyeloplasty is an excellent minimally invasive choice for the treatment of UPJO in HSK pediatric patients. The pediatric setting should prompt attention to every detail to avoid unfortunate complications.


2019 ◽  
Vol 46 (1) ◽  
pp. 48-56 ◽  
Author(s):  
Lenat Joffe ◽  
Sarah Dwyer ◽  
Julia L. Glade Bender ◽  
A. Lindsay Frazier ◽  
Elena J. Ladas

Sign in / Sign up

Export Citation Format

Share Document