scholarly journals Symptomatic Meckel's Diverticulum in Pediatric Patients—Case Reports and Systematic Review of the Literature

2019 ◽  
Vol 7 ◽  
Author(s):  
Daniel Keese ◽  
Udo Rolle ◽  
Stefan Gfroerer ◽  
Henning Fiegel
2018 ◽  
Vol 10 (6) ◽  
pp. 70-74 ◽  
Author(s):  
Eui Hyuk Chong ◽  
Dae Jung Kim ◽  
Sewha Kim ◽  
Gwangil Kim ◽  
Woo Ram Kim

2009 ◽  
Vol 7 (1) ◽  
Author(s):  
Hoey C. Koh ◽  
Blaithin Page ◽  
Catherine Black ◽  
Ian Brown ◽  
Stuart Ballantyne ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-9 ◽  
Author(s):  
Sara Díaz Angulo ◽  
Joanna Szram ◽  
Jenny Welch ◽  
Julie Cannon ◽  
Paul Cullinan

Background. The risks of occupational asthma (OA) from antibiotics are uncertain. We report 4 new cases and a systematic review of the literature. Methods. Cases were identified through a specialist clinic, each underwent specific provocation testing (SPT). We subsequently reviewed the published literature. Results. The patients were employed in the manufacture of antibiotics; penicillins were implicated in three cases, in the fourth erythromycin, not previously reported to cause OA. In two, there was evidence of specific IgE sensitisation. At SPT each developed a late asthmatic reaction and increased bronchial hyperresponsiveness. 36 case reports have been previously published, 26 (citing penicillins or cephalosporins). Seven cross-sectional workplace-based surveys found prevalences of 5–8%. Conclusions. OA in antibiotic manufacturers may be more common than is generally recognised. Its pathogenesis remains unclear; immunological tests are of uncertain value and potential cases require confirmation with SPT. Further study of its frequency, mechanisms, and diagnosis is required.


PEDIATRICS ◽  
1957 ◽  
Vol 20 (1) ◽  
pp. 98-100
Author(s):  
Stanley E. Crawford

THE PURPOSE of this paper is to report a recent case of an umbilical polyp and intestinal obstruction during the neonatal period. Umbilical polyps are rare. When present, they may be associated with Meckel's diverticulum because both are remnants of the omphalomesenteric duct. The presence of the visible polyp may give an external clue to otherwise obscure intraabdominal symptoms. A review of the literature earlier than 1916 is well summarized in a book by Thomas Cullen. This unusual volume lists six cases of umbilical polyp accompanied by other pathologic complications of Meckel's diverticulum. This author stressed that in these cases it should be pointed out to either the patient or his parents that possible intra-abdominal duct remnants may, at any time, give rise to symptoms such as intestinal obstruction. Penberthy and Benson reported a 9-year-old male with an umbilical polyp which had been present since birth and was without discharge. This youngster died following operation for intestinal obstruction due to volvulus about the diverticulum and its fibrous connection with the umbilical polyp. These authors pleaded for early elective operations in these cases prior to such complications. Gross gave other reasons for observation, and exploration at a reasonably early age, if a Meckel's diverticulum is suspected. Peritonitis from a ruptured Meckel's diverticulum is peculiarly dangerous; in young children the protecting omentum is inadequate and the migrating nature of the anomaly adds to the danger. Fluid from perforation of a diverticulum is usually of greater volume than that found in appendiceal rupture and abscess.


2018 ◽  
Vol 89 (4) ◽  
pp. 442-443 ◽  
Author(s):  
Bryan J. L. Buan ◽  
Heidi S. Y. Chang ◽  
Shi Wang ◽  
Choon Seng Chong

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Shashwat Mishra ◽  
Graham Martin ◽  
Ashim Chowdhury ◽  
Biju Aravind

Abstract Case An 85-year-old man underwent elective resection for a large proximal transverse colon tumour. At the time of this open extended right hemicolectomy, a Meckel’s diverticulum was identified in the ileum, but not resected considering the age and character of the diverticulum. However, on the sixth post-operative day, he developed small bowel obstructive symptoms which required a reoperation. It was found that the cause of obstruction was identified as a long pedunculated Meckel’s diverticulum wrapped 15 centimetres proximal to the anastomosis. Considering the general condition of the patient and co-morbidities, resection of the Meckel’s diverticulum and loop ileostomy was performed. The patient has now recovered and is being followed up in the community awaiting stoma reversal. Background Occurring in 2% of the population, Meckel’s diverticulum is the most common congenital gastrointestinal malformation. Complications of a Meckel’s diverticulum include obstruction, haemorrhage, perforation, diverticulitis and intussusception. Most complications manifest in childhood and are less likely to occur in adults. The indication for resection of incidental Meckel’s diverticula in an adults is still debated amongst surgeons. Discussion and Conclusion This case demonstrates an unfortunate scenario of a post-operative complication from an abnormality detected at the time of the index surgery. A recent systematic review has shown that evidence in literature remains controversial for resection in asymptomatic Meckel’s Diverticulum. There are even scoring systems to facilitate decisions in such situations. This case offers an interesting perspective where morbidity may have been reduced if resection was undertaken.


2020 ◽  
Vol 2020 ◽  
pp. 1-11
Author(s):  
Nicole Pini ◽  
Martina Ceccoli ◽  
Patrizia Bergonzini ◽  
Lorenzo Iughetti

Background and Objective. Grisel’s syndrome is a rare syndrome characterized by nontraumatic rotatory subluxation of the atlantoaxial joint. It usually affects children and typically presents with torticollis after ear, nose, and throat (ENT) surgery or head and neck infections. In the pediatric literature, there is only a small amount of available data; moreover, no systematic review has been previously done with focus on the pediatric population. We report our experience of two cases, and we provide a systematic review on Grisel’s syndrome in children in order to offer a deeper insight about its clinical presentation, its current diagnosis, and principles of treatment. Case Reports and Review. We describe two boys of 9 and 8 years old, who developed atlantoaxial subluxation after adenoidectomy. Considering the early diagnosis, a conservative treatment was chosen, with no recurrence and no sequelae at follow-up. We identified 114 case reports, of which 90 describe children, for a total of 171 pediatric patients. Of the 154 cases in which cause was reported, 59.7% presented a head and neck infection and 35.7% had previous head and neck surgery. There is no sex prevalence (49.7% males versus 50.2% females). Mean delay in diagnosis is 33 days. Eight % of the patients had neurological impairment of the 165 cases which mentioned treatment, 96% underwent a conservative treatment, of whom the 8.8% recurred with the need of surgery. As a whole, 12% underwent surgery as a first- or second-line treatment. 3 6% of the patients whose follow-up was reported developed a sequela, minor limitation of neck movement being the most frequent. Conclusion. Grisel’s syndrome should be suspected in children with painful unresponsive torticollis following ENT procedures or head and neck inflammation. CT scan with 3D reconstruction is the gold standard for diagnosis, allowing the identification of the subluxation and the classification according to the Fielding–Hawkins grading system. Surgical treatment is indicated in case of high-grade instability or failure of conservative treatment. Review of the literature shows how early diagnosis based on clinical and radiological evaluation is crucial in order to avoid surgical treatment and neurologic sequelae.


2020 ◽  
Vol 36 (12) ◽  
pp. 2927-2938
Author(s):  
Joham Choque-Velasquez ◽  
Roberto Colasanti ◽  
Szymon Baluszek ◽  
Julio Resendiz-Nieves ◽  
Sajjad Muhammad ◽  
...  

Abstract Introduction We present a consecutive case series and a systematic review of surgically treated pediatric PCs. We hypothesized that the symptomatic PC is a progressive disease with hydrocephalus at its last stage. We also propose that PC microsurgery is associated with better postoperative outcomes compared to other treatments. Methods The systematic review was conducted in PubMed and Scopus. No clinical study on pediatric PC patients was available. We performed a comprehensive evaluation of the available individual patient data of 43 (22 case reports and 21 observational series) articles. Results The review included 109 patients (72% females). Ten-year-old or younger patients harbored smaller PC sizes compared to older patients (p < 0.01). The pediatric PCs operated on appeared to represent a progressive disease, which started with unspecific symptoms with a mean cyst diameter of 14.5 mm, and progressed to visual impairment with a mean cyst diameter of 17.8 mm, and hydrocephalus with a mean cyst diameter of 23.5 mm in the final stages of disease (p < 0.001). Additionally, 96% of patients saw an improvement in their symptoms or became asymptomatic after surgery. PC microsurgery linked with superior gross total resection compared to endoscopic and stereotactic procedures (p < 0.001). Conclusions Surgically treated pediatric PCs appear to behave as a progressive disease, which starts with cyst diameters of approximately 15 mm and develops with acute or progressive hydrocephalus at the final stage. PC microneurosurgery appears to be associated with a more complete surgical resection compared to other procedures.


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