scholarly journals Relation of early childhood growth and wheezing phenotypes to adult lung function

2011 ◽  
Vol 46 (10) ◽  
pp. 956-963 ◽  
Author(s):  
Duane L. Sherrill ◽  
Stefano Guerra ◽  
Anne L. Wright ◽  
Wayne J. Morgan ◽  
Fernando D. Martinez
Author(s):  
Maribel Casas Sanahuja ◽  
Herman T. Den Dekker ◽  
Claudia J. Kruithof ◽  
Irwin K. Reiss ◽  
Martine Vrijheid ◽  
...  

Thorax ◽  
2009 ◽  
Vol 64 (3) ◽  
pp. 228-232 ◽  
Author(s):  
R J Hancox ◽  
R Poulton ◽  
J M Greene ◽  
C R McLachlan ◽  
M S Pearce ◽  
...  

Thorax ◽  
2015 ◽  
Vol 71 (10) ◽  
pp. 916-922 ◽  
Author(s):  
Yutong Cai ◽  
Seif O Shaheen ◽  
Rebecca Hardy ◽  
Diana Kuh ◽  
Anna L Hansell

2020 ◽  
Vol 56 (6) ◽  
pp. 2000157
Author(s):  
Gabriela P. Peralta ◽  
Alicia Abellan ◽  
Parisa Montazeri ◽  
Mikel Basterrechea ◽  
Ana Esplugues ◽  
...  

Previous studies have related early postnatal growth with later lung function but their interpretation is limited by the methods used to assess a child's growth. We aimed to assess the association of early childhood growth, measured by body mass index (BMI) trajectories up to 4 years, with lung function at 7 years.We included 1257 children from the Spanish Infancia y Medio Ambiente population-based birth cohort. Early childhood growth was classified into five categories based on BMI trajectories up to 4 years previously identified using latent class growth analysis. These trajectories differed in birth size (“lower”, “average”, “higher”) and in BMI gain velocity (“slower”, “accelerated”). We related these trajectories to lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC), FEV1/FVC and forced expiratory flow at 25%–75% of FVC (FEF25–75%)) at 7 years, using multivariable mixed regression.Compared to children with average birth size and slower BMI gain (reference), children with higher birth size and accelerated BMI gain had a higher FVC % pred (3.3%, 95% CI 1.0%–5.6%) and a lower FEV1/FVC % pred (−1.5%, 95% CI −2.9%–−0.1%) at 7 years. Similar associations were observed for children with lower birth size and accelerated BMI gain. Children with lower birth size and slower BMI gain had lower FVC % pred at 7 years. No association was found for FEF25–75%.Independently of birth size, children with accelerated BMI gain in early childhood had higher lung function at 7 years but showed airflow limitation. Children with lower birth size and slower BMI gain in early childhood had lower lung function at 7 years.


Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 1416-P
Author(s):  
MAISA N. FEGHALI ◽  
STEVE CARITIS ◽  
CHRISTINA M. SCIFRES

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Thorsten Braun ◽  
Vivien Filleböck ◽  
Boris Metze ◽  
Christoph Bührer ◽  
Andreas Plagemann ◽  
...  

AbstractObjectivesTo compare the long-term effects of antenatal betamethasone (ANS, ≤16 mg, =24 mg and >24 mg) in twins on infant and childhood growth.MethodsA retrospective cohort follow up study among 198 twins after ANS including three time points: U1 first neonatal examination after birth and in the neonatal period; U7 examination from the 21st to the 24th month of life and U9 examination from the 60th to the 64th month of life using data from copies of the children’s examination booklets. Inclusion criteria are twin pregnancies with preterm labor, cervical shortening, preterm premature rupture of membranes, or vaginal bleeding, and exposure to ANS between 23+5 and 33+6 weeks. Outcome measures are dosage-dependent and sex-specific effects of ANS on growth (body weight, body length, head circumference, body mass index and ponderal index) up to 5.3 years.ResultsOverall, 99 live-born twin pairs were included. Negative effects of ANS on fetal growth persisted beyond birth, altered infant and childhood growth, independent of possible confounding factors. Overall weight percentile significantly decreased between infancy and early childhood by 18.8%. Birth weight percentiles significantly changed in a dose dependent and sex specific manner, most obviously in female-female and mixed pairs. The ponderal index significantly decreased up to 42.9%, BMI index increased by up to 33.8%.ConclusionsANS results in long-term alterations in infant and childhood growth. Changes between infancy and early childhood in ponderal mass index and BMI, independent of dose or twin pair structure, might indicate an ANS associated increased risk for later life disease.SynopsisFirst-time report on long-term ANS administration growth effects in twin pregnancies, showing persisting alterations beyond birth in infant and childhood growth up to 5.3 years as potential indicator of later life disease risk.


2017 ◽  
Vol 119 (2) ◽  
pp. 153-159 ◽  
Author(s):  
Alison G. Lee ◽  
Yueh-Hsiu M. Chiu ◽  
Maria J. Rosa ◽  
Sheldon Cohen ◽  
Brent A. Coull ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document