Lung function tests in neonates and infants with chronic lung disease: Lung and chest-wall mechanics

2006 ◽  
Vol 41 (4) ◽  
pp. 291-317 ◽  
Author(s):  
Monika Gappa ◽  
J. Jane Pillow ◽  
Julian Allen ◽  
Oscar Mayer ◽  
Janet Stocks
Keyword(s):  
Lung Function ◽  
Lung Disease ◽  
Chest Wall ◽  
Chronic Lung Disease ◽  
Lung Function Tests ◽  
Chest Wall Mechanics ◽  
Function Tests ◽  
Neonates And Infants

Lung Function Tests in Neonates and Infants with Chronic Lung Disease: Forced Expiratory Maneuvers

2006 ◽  
Vol 41 (3) ◽  
pp. 199-214 ◽  
Author(s):  
Sooky Lum ◽  
Georg Hülskamp ◽  
Peter Merkus ◽  
Eugenio Baraldi ◽  
Ward Hofhuis ◽  
...  
Keyword(s):  
Lung Function ◽  
Lung Disease ◽  
Chronic Lung Disease ◽  
Lung Function Tests ◽  
Function Tests ◽  
Neonates And Infants

scholarly journals Novel magnetic resonance technique for functional imaging of cystic fibrosis lung disease

2017 ◽  
Vol 50 (6) ◽  
pp. 1701464 ◽  
Author(s):  
Sylvia Nyilas ◽  
Grzegorz Bauman ◽  
Gregor Sommer ◽  
Enno Stranzinger ◽  
Orso Pusterla ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Magnetic Resonance ◽  
Lung Function ◽  
Contrast Agents ◽  
Lung Disease ◽  
Functional Mri ◽  
Functional Impairment ◽  
Structural Mri ◽  
Lung Function Tests ◽  
Function Tests

Lung function tests are commonly used to monitor lung disease in cystic fibrosis (CF). While practical, they cannot locate the exact origin of functional impairment. Contemporary magnetic resonance imaging (MRI) techniques provide information on the location of disease but the need for contrast agents constrains their repeated application. We examined the correlation between functional MRI, performed without administration of contrast agent, and lung clearance index (LCI) from nitrogen multiple-breath washout (N2-MBW).40 children with CF (median (range) age 12.0 (6–18) years) and 12 healthy age-matched controls underwent functional and structural MRI and lung function tests on the same day. Functional MRI provided semiquantitative measures of perfusion (RQ) and ventilation (RFV) impairment as percentages of affected lung volume. Morphological MRI was evaluated using CF-specific scores. LCI measured global ventilation inhomogeneity.MRI detected functional impairment in CF:RFV19–38% andRQ16–35%.RFVandRQcorrelated strongly with LCI (r=0.76, p<0.0001 and r=0.85, p<0.0001, respectively), as did total morphology score (r=0.81, p<0.0001). All indices differed significantly between patients with CF and healthy controls (p<0.001).Noninvasive functional MRI is a promising method to detect and visualise perfusion and ventilation impairment in CF without the need for contrast agents.

Novel lung function tests in patients with interstitial lung disease (ILD)

2016 ◽  
Author(s):  
Frederik Trinkmann ◽  
Katharina Roth ◽  
Daniel Saur ◽  
Martin Borggrefe ◽  
Joachim Saur ◽  
...  
Keyword(s):  
Interstitial Lung Disease ◽  
Lung Function ◽  
Lung Disease ◽  
Lung Function Tests ◽  
Function Tests

Chest wall mechanics: Effects of acute and chronic lung disease

1989 ◽  
Vol 22 (6-7) ◽  
pp. 559-564 ◽  
Author(s):  
Shlomo A. Ben-Haim ◽  
Gerald M. Saidel
Keyword(s):  
Lung Disease ◽  
Chest Wall ◽  
Chronic Lung Disease ◽  
Chest Wall Mechanics
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