Relationship between FEV1 and peak oxygen uptake in children with cystic fibrosis

2005 ◽  
Vol 40 (4) ◽  
pp. 324-329 ◽  
Author(s):  
Paul Pianosi ◽  
John LeBlanc ◽  
Anthony Almudevar
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Peak Oxygen Uptake

PREDICTORS OF PEAK OXYGEN UPTAKE IN PATIENTS WITH CYSTIC FIBROSIS

1992 ◽  
Vol 24 (Supplement) ◽  
pp. S161
Author(s):  
P. Nixon ◽  
D. Orenstein ◽  
S. Kelsay
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Peak Oxygen Uptake

Estimating peak oxygen uptake in adolescents with cystic fibrosis

2013 ◽  
Vol 99 (1) ◽  
pp. 21-25 ◽  
Author(s):  
M. S. Werkman ◽  
E. H. J. Hulzebos ◽  
P. J. M. Helders ◽  
B. G. M. Arets ◽  
T. Takken
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Peak Oxygen Uptake

Supramaximal Verification of Peak Oxygen Uptake in Adolescents With Cystic Fibrosis

2011 ◽  
Vol 23 (1) ◽  
pp. 15-21 ◽  
Author(s):  
Maarten S. Werkman ◽  
Hendrik J. Hulzebos ◽  
Pauline B. van de Weert-van Leeuwen ◽  
Hubertus G.M. Arets ◽  
Paul J.M. Helders ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Peak Oxygen Uptake

scholarly journals Peak Oxygen Uptake and Mortality in Cystic Fibrosis: Systematic Review and Meta-Analysis

2018 ◽  
Vol 64 (1) ◽  
pp. 91-98 ◽  
Author(s):  
Fernanda Maria Vendrusculo ◽  
João Paulo Heinzmann-Filho ◽  
Juliana Severo da Silva ◽  
Margarita Perez Ruiz ◽  
Márcio Vinícius Fagundes Donadio
Keyword(s):  
Systematic Review ◽  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Meta Analysis ◽  
Peak Oxygen Uptake

scholarly journals Supra-maximal verification of peak oxygen uptake in adolescents with cystic fibrosis

2010 ◽  
Vol 9 ◽  
pp. S68
Author(s):  
M. Werkman ◽  
E. Hulzebos ◽  
P. van de Weert-Van Leeuwen ◽  
B. Arets ◽  
P. Helders ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Peak Oxygen Uptake

Prediction of peak oxygen uptake using the modified shuttle test in children and adolescents with cystic fibrosis

2019 ◽  
Vol 54 (4) ◽  
pp. 386-392 ◽  
Author(s):  
Fernanda M. Vendrusculo ◽  
João P. Heinzmann‐Filho ◽  
Natália E. Campos ◽  
Mailise F. Gheller ◽  
Ingrid S. de Almeida ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Children And Adolescents ◽  
Peak Oxygen Uptake

scholarly journals Cardiopulmonary exercise testing with supramaximal verification produces a safe and valid assessment of V̇o2max in people with cystic fibrosis: a retrospective analysis

2018 ◽  
Vol 125 (4) ◽  
pp. 1277-1283 ◽  
Author(s):  
Adam J. Causer ◽  
Janis K. Shute ◽  
Michael H. Cummings ◽  
Anthony I. Shepherd ◽  
Victoria Bright ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Oxygen Uptake ◽  
Exercise Testing ◽  
Cardiopulmonary Exercise Testing ◽  
Peak Oxygen Uptake ◽  
Valid Measure ◽  
Exercise Tests ◽  
Cardiopulmonary Exercise ◽  
Adolescents And Adults ◽  
Maximal Effort

The validity and safety of using supramaximal verification (Smax) to confirm a maximal effort during cardiopulmonary exercise testing (CPET) in people with cystic fibrosis (CF) and/or those with severe disease has been questioned. Therefore, this study aimed to investigate these concerns in children, adolescents, and adults with mild-to-severe CF lung disease. Retrospective analysis of 17 pediatric and 28 adult participants with CF [age range: 9.2–62.9 y; forced expiratory volume in 1 s: 66.7% (range: 29.9%–102.3%); 30 men] who completed a routine ramp-incremental cycling test to determine peak oxygen uptake (V̇o2peak) was studied. Maximal oxygen uptake (V̇o2max) was subsequently confirmed by Smax at 110% of peak power output. All participants satisfied the criteria to verify a maximal effort during CPET. However, Smax-V̇o2peak exceeded ramp-V̇o2peak in 3/14 (21.4%) of pediatric and 6/28 (21.4%) adult exercise tests. A valid measurement of V̇o2max was attained in 85.7% of pediatric and 96.4% of adult exercise tests, as Smax-V̇o2peak did not exceed ramp-V̇o2peak by >9%. Adults ( n = 9) experienced a ≥5% reduction in arterial O2 saturation during CPET, 4 during both the ramp and Smax, 3 during only the ramp, and 2 during only Smax. Smax did not significantly worsen perceived breathing effort, chest tightness, throat narrowing, or exertion compared with ramp-incremental testing. Given the clinical importance of aerobic fitness in people with CF, incorporating Smax is recommended to provide a safe and valid measure of V̇o2max in children, adolescents, and adults who span the spectrum of CF disease severity. NEW & NOTEWORTHY Incorporating supramaximal verification into cardiopulmonary exercise testing protocols did not increase the frequency of adverse events or perceived discomfort versus a single-phase incremental exercise test in people with mild-to-severe cystic fibrosis. Furthermore, a valid measure of maximal oxygen uptake (V̇o2max) was obtained from 85.7% of pediatric and 96.4% of adult exercise tests, whereas peak oxygen uptake underestimated aerobic fitness in comparison with V̇o2max in 21.4% of cases (by up to 24.4%).

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