scholarly journals High-Resolution Label-Free Detection of Biocompatible Polymeric Nanoparticles in Cells

2018 ◽  
Vol 35 (3) ◽  
pp. 1700457 ◽  
Author(s):  
Elisabetta Pancani ◽  
Jérémie Mathurin ◽  
Sylvie Bilent ◽  
Marie-Françoise Bernet-Camard ◽  
Alexandre Dazzi ◽  
...  
Keyword(s):  
High Resolution ◽  
Polymeric Nanoparticles ◽  
Label Free ◽  
Label Free Detection ◽  
In Cells

scholarly journals Biocompatible Nanoparticles: High-Resolution Label-Free Detection of Biocompatible Polymeric Nanoparticles in Cells (Part. Part. Syst. Charact. 3/2018)

2018 ◽  
Vol 35 (3) ◽  
pp. 1870008
Author(s):  
Elisabetta Pancani ◽  
Jérémie Mathurin ◽  
Sylvie Bilent ◽  
Marie-Françoise Bernet-Camard ◽  
Alexandre Dazzi ◽  
...  
Keyword(s):  
High Resolution ◽  
Polymeric Nanoparticles ◽  
Label Free ◽  
Biocompatible Nanoparticles ◽  
Label Free Detection ◽  
In Cells

Biomimetic Nanochannel-Ionchannel Hybrid for Ultrasensitive and Label-Free Detection of MicroRNA in Cells

2019 ◽  
Vol 91 (5) ◽  
pp. 3582-3589 ◽  
Author(s):  
Xiao-Ping Zhao ◽  
Fei-Fei Liu ◽  
Wen-Chao Hu ◽  
Muhammad Rizwan Younis ◽  
Chen Wang ◽  
...  
Keyword(s):  
Label Free ◽  
Label Free Detection ◽  
In Cells

scholarly journals Label-Free Detection of Mitochondrial Distribution in Cells by Nonresonant Raman Microspectroscopy

2007 ◽  
Vol 93 (2) ◽  
pp. 668-673 ◽  
Author(s):  
Christian Matthäus ◽  
Tatyana Chernenko ◽  
Judith A. Newmark ◽  
Carol M. Warner ◽  
Max Diem
Keyword(s):  
Raman Microspectroscopy ◽  
Label Free ◽  
Label Free Detection ◽  
Mitochondrial Distribution ◽  
In Cells

scholarly journals The Role of Surface Chemistry in the Efficacy of Protein and DNA Microarrays for Label-Free Detection: An Overview

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1026
Author(s):  
Elisa Chiodi ◽  
Allison M. Marn ◽  
Matthew T. Geib ◽  
M. Selim Ünlü
Keyword(s):  
Surface Chemistry ◽  
Surface Functionalization ◽  
Dna Microarrays ◽  
Label Free ◽  
Polymeric Coatings ◽  
Label Free Detection ◽  
Particle Imaging ◽  
Single Particle Imaging ◽  
The Impact

The importance of microarrays in diagnostics and medicine has drastically increased in the last few years. Nevertheless, the efficiency of a microarray-based assay intrinsically depends on the density and functionality of the biorecognition elements immobilized onto each sensor spot. Recently, researchers have put effort into developing new functionalization strategies and technologies which provide efficient immobilization and stability of any sort of molecule. Here, we present an overview of the most widely used methods of surface functionalization of microarray substrates, as well as the most recent advances in the field, and compare their performance in terms of optimal immobilization of the bioreceptor molecules. We focus on label-free microarrays and, in particular, we aim to describe the impact of surface chemistry on two types of microarray-based sensors: microarrays for single particle imaging and for label-free measurements of binding kinetics. Both protein and DNA microarrays are taken into consideration, and the effect of different polymeric coatings on the molecules’ functionalities is critically analyzed.

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