A non-enzymatic model based on an acyl transfer reaction for the formation of energy-rich acetyl phosphate in organic solvents and in a biphasic system

2010 ◽  
Vol 23 (8) ◽  
pp. 735-742
Author(s):  
Luciano A. Giusti ◽  
Vanderlei G. Machado
Keyword(s):  
Organic Solvents ◽  
Transfer Reaction ◽  
Acyl Transfer ◽  
Biphasic System ◽  
Acetyl Phosphate ◽  
Model Based ◽  
Enzymatic Model ◽  
Acyl Transfer Reaction

A phosphate-catalysed acyl transfer reaction. Hydrolysis of 4-nitrophenyl acetate in phosphate buffers

1984 ◽  
Vol 37 (12) ◽  
pp. 2559 ◽  
Author(s):  
CJ O'Conner ◽  
RG Wallace
Keyword(s):  
Transfer Reaction ◽  
Acyl Transfer ◽  
Acetyl Phosphate ◽  
Linear Rate ◽  
First Order ◽  
Buffer Solutions ◽  
Phosphate Species ◽  
Pseudo First Order ◽  
Acyl Transfer Reaction ◽  
Hydrolysis Of

The pseudo-first-order rate constants for the phosphate-catalysed hydrolysis of 4-nitrophenyl acetate have been determined in water at 310.5 K. The reaction has been followed spectrophotometrically by the disappearance of the ester and with n.m.r, spectroscopy by the appearance of both acetyl phosphate and the acetate ion and by the disappearance of ester. A phosphate-catalysed acyl transfer mechanism has been identified, in which the aryl ester is attacked by phosphate to give acetyl phosphate which is subsequently hydrolysed by water to acetate ion and regenerated catalyst. At concentrations of total phosphate exceeding 1.0 mol dm-3 the presence of dimeric phosphate species causes the appearance of a non-linear rate-concentration profile. Catalysis has been also been observed in 2,2'-(propane-1,3-diyldiimino)bis(propane-1,3-diol) buffer solutions.

Organocatalytic asymmetric Michael/hemiketalization/acyl transfer reaction of 1,3-propanediones with (E)-2-(2-nitrovinyl)phenols

2019 ◽  
Vol 17 (7) ◽  
pp. 1718-1721 ◽  
Author(s):  
Nimisha Bania ◽  
Subhas Chandra Pan
Keyword(s):  
Transfer Reaction ◽  
Acyl Transfer ◽  
Keto Ester ◽  
Acyl Transfer Reaction

An organocatalytic asymmetric cascade Michael/hemiketalization/acyl transfer reaction between (E)-2-(2-nitrovinyl)phenols and 1,3-propanediones is disclosed to generate products having keto, ester and nitro functionalities.

Synthesis of strained cyclic peptides via an aza-Michael–acyl-transfer reaction cascade

2012 ◽  
Vol 48 (65) ◽  
pp. 8084 ◽  
Author(s):  
Jochem P. A. Rutters ◽  
Yvette Verdonk ◽  
Remko de Vries ◽  
Steen Ingemann ◽  
Henk Hiemstra ◽  
...  
Keyword(s):  
Cyclic Peptides ◽  
Transfer Reaction ◽  
Acyl Transfer ◽  
Acyl Transfer Reaction

Organocatalytic Asymmetric Conjugate Addition and Cascade Acyl Transfer Reaction of α-Nitroketones

2011 ◽  
Vol 76 (15) ◽  
pp. 6230-6239 ◽  
Author(s):  
Rui-jiong Lu ◽  
Yun-yun Yan ◽  
Jin-jia Wang ◽  
Quan-sheng Du ◽  
Shao-zhen Nie ◽  
...  
Keyword(s):  
Transfer Reaction ◽  
Conjugate Addition ◽  
Acyl Transfer ◽  
Acyl Transfer Reaction
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