Redox reactions of copper(II) upon electrospray ionization in the presence of acridine ligands with an amide side chain

2009 ◽  
Vol 22 (3) ◽  
pp. 229-233 ◽  
Author(s):  
Aura Tintaru ◽  
Laurence Charles ◽  
Petr Milko ◽  
Jana Roithová ◽  
Detlef Schröder
Keyword(s):  
Electrospray Ionization ◽  
Redox Reactions ◽  
Side Chain ◽  
Amide Side Chain

The influence of chirality in the amide side chain on the carbonyl orientation in rotational isomers of 3-carbamoylpyridinium halides

1988 ◽  
pp. 230 ◽  
Author(s):  
Loek A. M. Bastiaansen ◽  
Ton J. M. Vermeulen ◽  
Henk M. Buck ◽  
Wilberth J. J. Smeets ◽  
Jan A. Kanters ◽  
...  
Keyword(s):  
Side Chain ◽  
Rotational Isomers ◽  
Amide Side Chain

On the turn-inducing properties of asparagine: the structuring role of the amide side chain, from isolated model peptides to crystallized proteins

2018 ◽  
Vol 20 (5) ◽  
pp. 3411-3423 ◽  
Author(s):  
S. Habka ◽  
W. Y. Sohn ◽  
V. Vaquero-Vara ◽  
M. Géléoc ◽  
B. Tardivel ◽  
...  
Keyword(s):  
Gas Phase ◽  
Laser Spectroscopy ◽  
Protein Structures ◽  
Side Chain ◽  
Amide Side Chain ◽  
Model Peptides

The anchoring properties of an asparagine (Asn) residue to its local backbone environment in turn model peptides is characterized using gas phase laser spectroscopy and compared to crystallized protein structures.

Radioimmunoassay of lysergic acid diethylamide (LSD) in serum and urine by using antisera of different specificities.

1977 ◽  
Vol 23 (2) ◽  
pp. 169-174 ◽  
Author(s):  
W A Ratcliffe ◽  
S M Fletcher ◽  
A C Moffat ◽  
J G Ratcliffe ◽  
W A Harland ◽  
...  
Keyword(s):  
Biological Fluids ◽  
Cross Reactivity ◽  
High Titre ◽  
Lysergic Acid ◽  
Side Chain ◽  
Satisfactory Method ◽  
Related Compounds ◽  
Amide Side Chain ◽  
Different Parts ◽  
Serum And Urine

Abstract We raised high-titre antisera to two LSD-bovine serum albumin conjugates, one linked via the indole nitrogen, the other via the amide side-chain. The antisera were specific for different parts of the LSD molecule, as demonstrated by cross-reactivity studies with LSD, its metabolites, ergot alkoloids, and closely related compounds. The antisera were used to develop a double-antibody radioimmunoassay with a detection limit of about 0.4 mug of LSD per liter of unextracted urine or serum. We saw no nonspecific interference by urine, serum, or from a series of commonly used drugs. There was good correlation between immunoassay values obtained with the two antisera (r = 0.91). However, the antiserum linked via the indole nitrogen gave consistently higher results for samples from persons who had taken LSD, owing to greater cross-reactivity with LSD metabolites. Radioimmunoassay by use of two such antisera is a more specific screening procedure for LSD abuse than has been available previously. In addition, antisera cross-reacting with LSD metabolites allow measurement of these compounds, for which there is no satisfactory method at the concentrations found in biological fluids in man.

Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology. Part 2: Propellane derivatives with an amide side chain

2012 ◽  
Vol 22 (8) ◽  
pp. 2775-2779 ◽  
Author(s):  
Hiroshi Nagase ◽  
Junko Akiyama ◽  
Ryo Nakajima ◽  
Shigeto Hirayama ◽  
Toru Nemoto ◽  
...  
Keyword(s):  
Side Chain ◽  
Amide Side Chain

scholarly journals 2,2′-(Diselane-1,2-diyl)bis(N,N-dimethylnicotinamide)

IUCrData ◽  
2017 ◽  
Vol 2 (6) ◽  
Author(s):  
Zhiqiang Guo ◽  
Yakong Wang ◽  
Ying Xu ◽  
Xuehong Wei
Keyword(s):  
Dihedral Angle ◽  
Title Compound ◽  
Pyridine Ring ◽  
Side Chain ◽  
Compound C ◽  
Amide Side Chain

The title compound, C16H18N4O2Se2, is centrosymmetric. The dihedral angle between the pyridine ring and the amide side chain is 56.20 (16)°. In the crystal, a weak C—H...O interaction links the molecules into [010] chains.

Oxidation of Acid, Base, and Amide Side-Chain Amino Acid Derivatives via Hydroxyl Radical

2018 ◽  
Vol 122 (19) ◽  
pp. 4956-4971 ◽  
Author(s):  
Jon Uranga ◽  
Jon I. Mujika ◽  
Rafael Grande-Aztatzi ◽  
Jon M. Matxain
Keyword(s):  
Amino Acid ◽  
Hydroxyl Radical ◽  
Side Chain ◽  
Amino Acid Derivatives ◽  
Acid Base ◽  
Amide Side Chain

scholarly journals Kinetics, degradation mechanisms and antibiotic activity reduction of chloramphenicol in aqueous solution by UV/H2O2 process

2021 ◽  
Author(s):  
Ardhendu Sekhar Giri ◽  
Animes Kumar Golder ◽  
Sankar Chakma
Keyword(s):  
Degradation Kinetics ◽  
Radical Scavenging ◽  
Side Chain ◽  
Order Model ◽  
Oxidation Number ◽  
E Coli ◽  
Radical Scavenging Capacity ◽  
Scavenging Capacity ◽  
The Mean ◽  
Amide Side Chain

Abstract In this study, the aim was to explore the effectiveness of the UV/H2O2 photolysis (UVP) process in terms of antimicrobial activity reduction and increasing the mean oxidation number of carbon (MONC) under the degradation of chloramphenicol (CHPL) drug. CHPL degradation kinetics and the effects of foreign anions on CHPL degradation were explored in this study. The order of the inhibition effect was found as Cl− > NO3− > HCO3− due to their different in HO• radical scavenging capacity. A pseudo-first-order model for CHPL degradation was well established, and the rate constant (kobs) was 2.93 × 10−2 min−1 (R2 = 0.98) in UVP. Thirteen intermediate products were detected in MS-chromatogram and were identified through different proposed degradation pathways. The cleavage of the amide side chain in CHPL was more effective in CHPL degradation due to an electrophilic attacks by HO. radicals on it. The inactivation rates of E. coli were decreased due to the reduction of -NO2 group into -NH2 functional group in CHPL that leads to the production of low toxic compounds on CHPL degradation.

One-Step Synthesis of β-Lactams with Retro-Amide Side Chain

Synthesis ◽  
2010 ◽  
Vol 2011 (01) ◽  
pp. 69-72
Author(s):  
Sławomir Makowiec ◽  
Karolina Janikowska ◽  
Natalia Pawelska
Keyword(s):  
Side Chain ◽  
One Step ◽  
Amide Side Chain
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