scholarly journals Front cover: Proteomic analysis of pear (Pyrus pyrifolia ) ripening process provides new evidence for the sugar/acid metabolism difference between core and mesocarp

PROTEOMICS ◽  
2016 ◽  
Vol 16 (23) ◽  
pp. NA-NA
Author(s):  
Zhen Gao ◽  
Chengjun Zhang ◽  
Meng Luo ◽  
Yusen Wu ◽  
Shuyan Duan ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Acid Metabolism ◽  
Pyrus Pyrifolia ◽  
Front Cover ◽  
Ripening Process ◽  
New Evidence

Proteomic analysis of pear (Pyrus pyrifolia) ripening process provides new evidence for the sugar/acid metabolism difference between core and mesocarp

PROTEOMICS ◽  
2016 ◽  
Vol 16 (23) ◽  
pp. 3025-3041 ◽  
Author(s):  
Zhen Gao ◽  
Chengjun Zhang ◽  
Meng Luo ◽  
Yusen Wu ◽  
Shuyan Duan ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Acid Metabolism ◽  
Pyrus Pyrifolia ◽  
Ripening Process ◽  
New Evidence

scholarly journals Front Cover: TMT‐Based Quantitative Proteomic Analysis Reveals Proteomic Changes Involved in Longevity

2019 ◽  
Vol 13 (4) ◽  
pp. 1970041
Author(s):  
Zongkui Wang ◽  
Rong Zhang ◽  
Fengjuan Liu ◽  
Peng Jiang ◽  
Jun Xu ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Front Cover ◽  
Quantitative Proteomic Analysis

scholarly journals Front Cover: Effects of let-7e on LPS-Stimulated THP-1 Cells Assessed by iTRAQ Proteomic Analysis

2018 ◽  
Vol 12 (5) ◽  
pp. 1870040
Author(s):  
Lian Gui ◽  
Qianqian Zhang ◽  
Yan Cai ◽  
Xiaohong Deng ◽  
Yingke Zhang ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Front Cover

scholarly journals Comparative Proteomic Analysis of Wild-Type Physcomitrella patens and an OPDA-Deficient Physcomitrella patens Mutant with Disrupted PpAOS1 and PpAOS2 Genes after Wounding

2020 ◽  
Author(s):  
Weifeng Luo ◽  
Setsuko Komatsu ◽  
Tatsuya Abe ◽  
Hideyuki Matsuura ◽  
Kosaku Talahashi
Keyword(s):  
Protein Synthesis ◽  
Proteomic Analysis ◽  
Vascular Plants ◽  
Acid Metabolism ◽  
Physcomitrella Patens ◽  
Energy Utilization ◽  
Wild Type Plant ◽  
Wild Type ◽  
In The Wild ◽  
Energy Synthesis

Wounding is a serious environmental stress in plants. Oxylipins such as jasmonic acid play an important role in defense against wounding. Mechanisms to adapt to wounding have been investigated in vascular plants; however, those mechanisms in nonvascular plants remain elusive. To examine the response to wounding in Physcomitrella patens, a model moss, a proteomic analysis of wounded P. patens was conducted. Proteomic analysis showed that wounding increased the abundance of proteins related to protein synthesis, amino acid metabolism, protein folding, photosystem, glycolysis, and energy synthesis. 12-Oxo-phytodienoic acid (OPDA) was induced by wounding and inhibited growth. Therefore, OPDA is considered a signaling molecule in this plant. Proteomic analysis of a P. patens mutant in which the PpAOS1 and PpAOS2 genes, which are involved in OPDA biosynthesis, are disrupted showed accumulation of proteins involved in protein synthesis in response to wounding in a similar way to the wild-type plant. In contrast, the fold-changes of the proteins in the wild-type plant were significantly different from those in the aos mutant. This study suggests that PpAOS gene expression enhances photosynthesis and effective energy utilization in response to wounding in P. patens.

scholarly journals Front Cover: iTRAQ-Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism

2018 ◽  
Vol 12 (3) ◽  
pp. 1870020
Author(s):  
Liming Shen ◽  
Kaoyuan Zhang ◽  
Chengyun Feng ◽  
Youjiao Chen ◽  
Shuiming Li ◽  
...  
Keyword(s):  
Proteomic Analysis ◽  
Protein Profile ◽  
Children With Autism ◽  
Front Cover

Front Cover: Comparative gel-based proteomic analysis of chemically crosslinked complexes in dystrophic skeletal muscle

2018 ◽  
Vol 39 (14) ◽  
pp. NA-NA
Author(s):  
Sandra Murphy ◽  
Margit Zweyer ◽  
Rustam R. Mundegar ◽  
Dieter Swandulla ◽  
Kay Ohlendieck
Keyword(s):  
Skeletal Muscle ◽  
Proteomic Analysis ◽  
Front Cover

scholarly journals Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment

2019 ◽  
Vol 20 (13) ◽  
pp. 3122 ◽  
Author(s):  
Abeer K. Malkawi ◽  
Afshan Masood ◽  
Zakia Shinwari ◽  
Minnie Jacob ◽  
Hicham Benabdelkamel ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Proteomic Analysis ◽  
Acid Metabolism ◽  
Muscular Atrophy ◽  
Liver Lipid ◽  
Nervous System Development ◽  
Nucleic Acid Metabolism ◽  
Biochemical Pathways ◽  
Proteomic Approach ◽  
And Function

Prolonged dexamethasone (Dex) administration leads to serious adverse and decrease brain and heart size, muscular atrophy, hemorrhagic liver, and presence of kidney cysts. Herein, we used an untargeted proteomic approach using liquid chromatography-tandem mass spectrometry (LC-MS/MS) for simultaneous identification of changes in proteomes of the major organs in Sprague–Dawley (SD rats post Dex treatment. The comparative and quantitative proteomic analysis of the brain, heart, muscle, liver, and kidney tissues revealed differential expression of proteins (n = 190, 193, 39, 230, and 53, respectively) between Dex-treated and control rats. Functional network analysis using ingenuity pathway analysis (IPA revealed significant differences in regulation of metabolic pathways within the morphologically changed organs that related to: (i) brain—cell morphology, nervous system development, and function and neurological disease; (ii) heart—cellular development, cellular function and maintenance, connective tissue development and function; (iii) skeletal muscle—nucleic acid metabolism, and small molecule biochemical pathways; (iv) liver—lipid metabolism, small molecular biochemistry, and nucleic acid metabolism; and (v) kidney—drug metabolism, organism injury and abnormalities, and renal damage. Our study provides a comprehensive description of the organ-specific proteomic profilesand differentially altered biochemical pathways, after prolonged Dex treatement to understand the molecular basis for development of side effects.

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