A new positive-type photoreactive polyimide precursor using 1,4-dihydropyridine derivative

1992 ◽  
Vol 32 (21) ◽  
pp. 1634-1641 ◽  
Author(s):  
Toshihiko Omote ◽  
Tsuguo Yamaoka
Keyword(s):  
Positive Type ◽  
Dihydropyridine Derivative ◽  
Polyimide Precursor

scholarly journals Interpolation in wavelet spaces and the HRT-conjecture

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Eirik Berge
Keyword(s):  
Compact Group ◽  
Wavelet Transforms ◽  
Reproducing Kernel ◽  
Reproducing Kernel Hilbert Space ◽  
Space Structure ◽  
Locally Compact Group ◽  
Locally Compact ◽  
Positive Type ◽  
Time Frequency ◽  
Hrt Conjecture

AbstractWe investigate the wavelet spaces $$\mathcal {W}_{g}(\mathcal {H}_{\pi })\subset L^{2}(G)$$ W g ( H π ) ⊂ L 2 ( G ) arising from square integrable representations $$\pi :G \rightarrow \mathcal {U}(\mathcal {H}_{\pi })$$ π : G → U ( H π ) of a locally compact group G. We show that the wavelet spaces are rigid in the sense that non-trivial intersection between them imposes strong restrictions. Moreover, we use this to derive consequences for wavelet transforms related to convexity and functions of positive type. Motivated by the reproducing kernel Hilbert space structure of wavelet spaces we examine an interpolation problem. In the setting of time–frequency analysis, this problem turns out to be equivalent to the HRT-conjecture. Finally, we consider the problem of whether all the wavelet spaces $$\mathcal {W}_{g}(\mathcal {H}_{\pi })$$ W g ( H π ) of a locally compact group G collectively exhaust the ambient space $$L^{2}(G)$$ L 2 ( G ) . We show that the answer is affirmative for compact groups, while negative for the reduced Heisenberg group.

Increased expression of collagen-binding heat shock protein 47 in murine bleomycin-induced pneumopathy

2003 ◽  
Vol 285 (4) ◽  
pp. L957-L963 ◽  
Author(s):  
Hiroshi Ishii ◽  
Hiroshi Mukae ◽  
Tomoyuki Kakugawa ◽  
Tetsuji Iwashita ◽  
Hideyuki Kaida ◽  
...  
Keyword(s):  
Heat Shock ◽  
Pulmonary Fibrosis ◽  
Heat Shock Protein ◽  
Smooth Muscle Actin ◽  
Protein A ◽  
Immunohistochemical Analysis ◽  
Rt Pcr ◽  
Heat Shock Protein 47 ◽  
Positive Type ◽  
Fibrotic Process

The 47-kDa heat shock protein 47 (HSP47) is a collagen-specific molecular chaperone that has been shown to play a major role during the processing and/or secretion of procollagen. Expression of HSP47 has been reported to increase in parallel with expression of collagens during the progression of various fibrosis models. The aim of the present study was to investigate the association between HSP47 expression and collagen accumulation in bleomycin (BLM)-induced murine fibrosis. We investigated the expression of HSP47 protein and mRNA using immunohistochemical analysis and semi-quantitative RT-PCR in murine BLM-induced pulmonary fibrosis. Immunohistochemical analysis showed that higher expression of HSP47 protein was present in BLM-induced pulmonary fibrosis compared with controls. HSP47 was localized predominantly in α-smooth muscle actin-positive myofibroblasts, F4/80 negative, surfactant protein-A-positive type II pneumocytes, and F4/80-positive macrophages. RT-PCR also demonstrated an increase of HSP47 mRNA expression in BLM-treated lungs. Moreover, the relative amounts of HSP47 mRNA correlated significantly with the lung hydroxyproline content as an indicator of pulmonary fibrosis in BLM-treated lungs ( r = 0.406, P <0.05). Our results suggest that these cells may play a role in the fibrotic process of BLM-treated lungs through upregulation of HSP47.

scholarly journals in vitro Effects of Calcium Antagonists PN 200-110, Nifedipine, and Nimodipine on Human and Canine Cerebral Arteries

1983 ◽  
Vol 3 (3) ◽  
pp. 354-361 ◽  
Author(s):  
E. Müller-Schweinitzer ◽  
P. Neumann
Keyword(s):  
Rank Order ◽  
Cerebral Arteries ◽  
Isometric Tension ◽  
Mesenteric Arteries ◽  
Organ Bath ◽  
Vasoconstrictor Response ◽  
Dihydropyridine Derivative ◽  
Basilar Arteries ◽  
In Vitro Effects

PN 200–110 [4-(2, 1, 3-benzoxadiazol - 4 -) - 1,4-dihydro - 2,6 - dimethyl - pyridine - 3,5 - dicarboxylic acid methyl 1-methylethyl ester], a new dihydropyridine derivative, was investigated by recording isometric tension on spiral strips from human and canine arteries in tissue baths at 37°C. Responses to increasing concentrations of CaCl2 were investigated in calcium-free depolarizing solution (60 mmol/L KCl in equimolar replacement for NaCl, 50 mmol/L TRIZMA buffer, pH 7.4). Comparison of those concentrations that reduced the vasoconstrictor response to 1.6 mmol/L CaCl2 by 50% revealed the following order of potencies on both human and canine arteries: PN 200–110 > nimodipine > nifedipine. Responses to 5-hydroxytryptamine (5-HT) and blood were investigated in Krebs–Henseleit solution (NaHCO3 buffer). On canine arteries, PN 200–110 antagonized responses to 5-HT when used at 10–30 pmol/L; it was ∼70 times more potent on basilar than on mesenteric arteries, whereas both nifedipine and nimodipine were, respectively, ∼10 and 6 times more potent on basilar than on mesenteric arteries. When canine basilar arteries were constricted by the addition of blood to the organ bath, each of the investigated dihydropyridine derivatives elicited concentration-dependent relaxation, producing the following order of potencies: PN 200–110 > nifedipine = nimodipine. On human anterior cerebral arteries, the blood-induced contractions were counteracted in the following rank order: PN 200–110 = nimodipine > nifedipine. The results suggest that due to its potent calcium-blocking activity on cerebral arteries, PN 200–110 might be of value for the prevention and treatment of cerebrovascular spasms following subarachnoid hemorrhage.

scholarly journals Positive-type Alkaline Developable Photosensitive Branched Polyamides with Low Degree of Branching and Diazonaphthoquinone as a Photosensitive Compound

2006 ◽  
Vol 38 (8) ◽  
pp. 827-834 ◽  
Author(s):  
Jijun Xiao ◽  
Yosuke Inai ◽  
Li Li ◽  
Teruaki Hayakawa ◽  
Masa-aki Kakimoto
Keyword(s):  
Degree Of Branching ◽  
Positive Type ◽  
Low Degree

In vitro assessment for vascular selectivity of a new dihydropyridine derivative, NB-818

1996 ◽  
Vol 301 (1-3) ◽  
pp. 99-106 ◽  
Author(s):  
Yuichi Hattori ◽  
Mitsuhiro Fukao ◽  
Hideki Houzen ◽  
Fazhi Qi ◽  
Yoichi Yamada ◽  
...  
Keyword(s):  
Vascular Selectivity ◽  
Dihydropyridine Derivative ◽  
In Vitro Assessment

The prevalence, immune profile, and clinical characteristics of children with celiac disease and type 1 diabetes mellitus in the state of Qatar

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Basma Haris ◽  
Ahmed Abdellatief ◽  
Houda Afyouni ◽  
Tasneem Abdel-Karim ◽  
Shayma Mohammed ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Type 1 Diabetes Mellitus ◽  
Clinical Characteristics ◽  
Family History Of Diabetes ◽  
Positive Type ◽  
Immune Profile ◽  
Insulin Autoantibody

Abstract Objectives Children with antibody positive type 1 diabetes mellitus (type 1 diabetes) are at an increased risk of developing celiac disease (CD) which suggests a common autoimmune basis with both high-risk human lymphocyte antigen (HLA) and non-HLA factors playing a role in the pathophysiology. We aim to describe the prevalence, immune profile, and clinical characteristics of children with CD who have type 1 diabetes mellitus in Qatar. Methods All children (aged 0–18 years) attending a regional diabetes clinic with antibody positive type 1 diabetes were screened for CD. Measurement of tissue transglutaminase IgA and IgG as well as anti-endomysial antibody, was done, clinical details about the birth history, family history of diabetes and CD, age of onset, and ethnicity were collected. Results Out of the 1,325 children with antibody positive type 1 diabetes, 54 were identified to have CD on screening and then confirmed on small bowel biopsy. The prevalence of CD in the type 1 diabetes childhood population in Qatar is 4.07%. CD and type 1 diabetes were more prevalent in the Qatari children (n=32) as compared to non-Qatari (n=22) and occurred mostly in the age group 6–10 years. The most common type 1 diabetes antibodies in children with CD were glutamic acid decarboxylase and insulin autoantibody. Twelve subjects were asymptomatic for CD symptoms and picked up only on screening. Conclusions The prevalence of CD in children with type 1 diabetes in Qatar is comparable to reports from around the world. Many children were asymptomatic and thus routine screening is recommended.

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