Totally bioresorbable composites prepared from poly(l -lactide)-co -(trimethylene carbonate) copolymers and poly(l -lactide)-co -(glycolide) fibers as cardiovascular stent material

2011 ◽  
Vol 52 (4) ◽  
pp. 741-750 ◽  
Author(s):  
Yaru Han ◽  
Xiaoyun Jin ◽  
Jian Yang ◽  
Zhongyong Fan ◽  
Zhiqian Lu ◽  
...  
2020 ◽  
Vol 189 ◽  
pp. 110831
Author(s):  
Ya-chen Hou ◽  
Jing-an Li ◽  
Shi-jie Zhu ◽  
Chang Cao ◽  
Jun-nan Tang ◽  
...  

2020 ◽  
Vol 35 (2) ◽  
pp. 158-168 ◽  
Author(s):  
Yuxiang Wu ◽  
Lei Chang ◽  
Jingan Li ◽  
Liguo Wang ◽  
Shaokang Guan

Magnesium alloy is generally accepted as a potential cardiovascular stent material due to its good mechanical properties, biocompatibility, and biodegradability, and has become one of the research hotspots in this field. However, too fast degradation rate and delayed surface endothelialization have been the bottleneck of further application of magnesium alloy stent. In this study, we selected Mg–Zn–Y–Nd, a kind of biodegradable magnesium alloy for cardiovascular stent, and passivated its surface by alkali heat treatment and silane treatment to improve the corrosion resistance, subsequently conjugated Arg–Glu–Asp–Val (REDV) peptide and anti-CD34 to promote endothelial cells adhesion and capture endothelial progenitor cells respectively, further improving surface endothelialization. In addition, the heparin was also immobilized to the Mg–Zn–Y–Nd surface for the consideration of anti-coagulation and anti-inflammation. Systematic material characterization and biological evaluation show that we have successfully developed this composite surface on Mg–Zn–Y–Nd alloy, and achieved multiple functions such as corrosion resistance, promoting endothelialization, and inhibiting platelet/macrophage adhesion.


2018 ◽  
Vol 33 (23) ◽  
pp. 4123-4133 ◽  
Author(s):  
Li Chen ◽  
Jingan Li ◽  
Shuo Wang ◽  
Shijie Zhu ◽  
Chao Zhu ◽  
...  

Abstract


2013 ◽  
Vol 54 (6) ◽  
pp. 1418-1426 ◽  
Author(s):  
Jianting Dong ◽  
Lan Liao ◽  
Li Shi ◽  
Zaishang Tan ◽  
Zhongyong Fan ◽  
...  

2014 ◽  
Vol 14 (6) ◽  
pp. 505-536 ◽  
Author(s):  
I. Neamtu ◽  
A.P. Chiriac ◽  
A. Diaconu ◽  
L.E. Nita ◽  
V. Balan ◽  
...  
Keyword(s):  

2019 ◽  
Vol 15 ◽  
pp. 963-970 ◽  
Author(s):  
Sora Park ◽  
Jeung Gon Kim

Mechanochemical polymerization is a rapidly growing area and a number of polymeric materials can now be obtained through green mechanochemical synthesis. In addition to the general merits of mechanochemistry, such as being solvent-free and resulting in high conversions, we herein explore rate acceleration under ball-milling conditions while the conventional solution-state synthesis suffer from low reactivity. The solvent-free mechanochemical polymerization of trimethylene carbonate using the organocatalysts 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU) and 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) are examined herein. The polymerizations under ball-milling conditions exhibited significant rate enhancements compared to polymerizations in solution. A number of milling parameters were evaluated for the ball-milling polymerization. Temperature increases due to ball collisions and exothermic energy output did not affect the polymerization rate significantly and the initial mixing speed was important for chain-length control. Liquid-assisted grinding was applied for the synthesis of high molecular weight polymers, but it failed to protect the polymer chain from mechanical degradation.


Author(s):  
Xiliang Liu ◽  
Song Liu ◽  
Shaomin Feng ◽  
Kaiqi Li ◽  
Youkun Fan ◽  
...  

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