Supplementary data collection with case-cohort analysis to address potential confounding in a cohort study of thromboembolism in oral contraceptive initiators matched on claims-based propensity scores

2008 ◽  
Vol 17 (3) ◽  
pp. 297-305 ◽  
Author(s):  
P. Mona Eng ◽  
John D. Seeger ◽  
Jeanne Loughlin ◽  
C. Robin Clifford ◽  
Sherry Mentor BA. ◽  
...  
Keyword(s):  
Cohort Study ◽  
Oral Contraceptive ◽  
Data Collection ◽  
Propensity Scores ◽  
Cohort Analysis ◽  
Supplementary Data

scholarly journals AB0393 PRE-EXISTING MORBIDITY AS A RISK FACTORS FOR MORTALITY IN IgA VASCULITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1224.3-1225
Author(s):  
J. Nossent ◽  
D. Preen ◽  
W. Raymond ◽  
H. Keen ◽  
C. Inderjeeth
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Mortality Rate ◽  
Data Collection ◽  
Premature Death ◽  
Iga Vasculitis ◽  
Risk Of Death ◽  
Increased Risk ◽  
Serious Infections ◽  
Western Australian

Background:IgA vasculitis is generally considered to be a self-limiting condition, but this is at odds with the increased mortality observed in adult patients with IgA vasculitis (1).Objectives:With sparse data on prognostic factors in IgAV, we investigated whether pre-existing conditions are risk factors for mortality in adult IgAV patients.Methods:Observational population-based cohort study using state-wide linked longitudinal health data for adults with IgAV (n=267) and matched controls (n=1080) between 1980-2015. Charlson comorbidity index (CCI) and serious infections (SI) were recorded over an extensive lookback period prior to diagnosis. Date and causes of death were extracted from the WA Death Registry. Mortality rate (deaths/1000 person-years) ratios (MRR) and time dependent survival analysis assessed the risk of death. Age and gender specific mortality rate data were obtained from the Australian Bureau of Statistics.Results:During 9.9 (±9.8) years lookback IgAV patients accrued higher CCI scores (2.60 vs1.50 p<0.001) and had higher risk of SI (OR 8.4, p<0.001), not fully explained by CCI scores. During 19 years follow-up, the risk of death in IgAV patients (n=137) was higher than in controls (n=397) (MRR 2.06, CI 1.70-2.50, p<0.01) and the general population (SMRR 5.64, CI 4.25, 7.53, p<0.001). Survival in IgAV was reduced at five (72.7 vs. 89.7 %) and twenty years (45.2% vs. 65.6 %) (both p<0.05). CCI (HR1.88, CI:1.25 - 2.73, p=0.001), renal failure (HR 1.48, CI: 1.04 - 2.22, p=0.03) and prior SI (HR 1.48, CI:1.01 – 2.16, p=0.04) were independent risk factors. Death from infections (5.8 vs 1.8%, p=0.02) was significantly more frequent in IgAV patients.Conclusion:Premorbid accrual of comorbidity is increased and predicts premature death in IgAV patients. However, comorbidity does not fully explain the increased risk of serious infections prior to diagnosis or the increased mortality due to infections in IgAV.References:[1]Villatoro-Villar M, Crowson CS, Warrington KJ, Makol A, Ytterberg SR, Koster MJ. Clinical Characteristics of Biopsy-Proven IgA Vasculitis in Children and Adults: A Retrospective Cohort Study. Mayo Clin Proc. 2019;94(9):1769-80.Acknowledgements:The authors would like to acknowledge the support of the Arthritis Foundation of WA and acknowledge the Western Australian Data Linkage Branch, the Western Australian Department of Health, and the data custodians of, the Hospital and Morbidity Data Collection, the Emergency Department Data Collection the WA Cancer Register and the WA Death Register for their assistance with the study.Disclosure of Interests:None declared

scholarly journals Cohort profile: the Men and Parenting Pathways (MAPP) Study: a longitudinal Australian cohort study of men’s mental health and well-being at the normative age for first-time fatherhood

BMJ Open ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. e047909
Author(s):  
Jacqui A Macdonald ◽  
Lauren M Francis ◽  
Helen Skouteris ◽  
George J Youssef ◽  
Liam G Graeme ◽  
...  
Keyword(s):  
Mental Health ◽  
Cohort Study ◽  
Data Collection ◽  
Online Survey ◽  
Sleep Problems ◽  
Meta Analysis ◽  
Well Being ◽  
Work And Family ◽  
Depressive Symptom Severity ◽  
Health And Well Being

PurposeThe Men and Parenting Pathways (MAPP) Study is a prospective investigation of men’s mental health and well-being across the normative age for transitioning to fatherhood. This includes trajectories and outcomes for men who do and do not become fathers across five annual waves of the study.ParticipantsAustralian resident, English-speaking men aged 28–32 years at baseline were eligible. Recruitment was over a 2-year period (2015–2017) via social and traditional media and through engagement with study partners. Eight hundred and eighteen eligible men consented to participate. Of these, 664 men completed the first online survey of whom 608 consented to ongoing participation. Of the ongoing sample, 83% have participated in at least two of the first three annual online surveys.Findings to dateThree waves of data collection are complete. The first longitudinal analysis of MAPP data, published in 2020, identified five profiles that characterise men’s patterns of depressive symptom severity and presentations of anger. Profiles indicating pronounced anger and depressive symptoms were associated with fathers’ lack of perceived social support, and problems with coparenting and bonding with infants. In a second study, MAPP data were combined with three other Australian cohorts in a meta-analysis of associations between fathers’ self-reported sleep problems up to 3 years postpartum and symptoms of depression, anxiety and stress. Adjusted meta-analytic associations between paternal sleep and mental health risk ranged from 0.25 to 0.37.Future plansMAPP is an ongoing cohort study. Waves 4 and 5 data will be ready for analyses at the end of 2021. Future investigations will include crossed-lagged and trajectory analyses that assess inter-relatedness and changing social networks, mental health, work and family life. A nested study of COVID-19 pandemic-related mental health and coping will add two further waves of data collection in a subsample of MAPP participants.

Simplifying spectroscopic supplementary data collection

2017 ◽  
pp. 6-10
Keyword(s):  
Data Collection ◽  
Peer Review ◽  
Spectroscopic Data ◽  
Supplementary Data ◽  
Low Resolution ◽  
Full Data ◽  
The Future ◽  
Published Paper ◽  
Low Resolution Images

Tony Davies and a number of others consider collecting supplementary spectroscopic data. Like Eurospec, the plan is to use such supplementary data not only to enhance the published paper, but also to aid thorough peer-review by allowing reviewers access to the full data rather than, as Tony puts it, “low-resolution images of data”. I’m sure you will be interested in a look at the future through this column.

Meta-analysis and machine learning-augmented mixed effects cohort analysis of improved diets among 5,847 medical trainees, providers, and patients

2021 ◽  
pp. 1-27
Author(s):  
Dominique J. Monlezun ◽  
Christopher Carr ◽  
Tianhua Niu ◽  
Francesco Nordio ◽  
Nicole DeValle ◽  
...  
Keyword(s):  
Machine Learning ◽  
Cohort Study ◽  
Nutrition Education ◽  
Meta Analysis ◽  
Cohort Analysis ◽  
Cost Effective ◽  
Number Needed To Treat ◽  
Nutrition Counseling ◽  
Medical Trainees ◽  
Hands On

Abstract Objective: We sought to produce the first meta-analysis (of medical trainee competency improvement in nutrition counseling) informing the first cohort study of patient diet improvement through medical trainees and providers counseling patients on nutrition. Design: (Part A) A systematic review and meta-analysis informing (Part B) the intervention analyzed in the world’s largest prospective multi-center cohort study on hands-on cooking and nutrition education for medical trainees, providers, and patients. Settings: (A) Medical educational institutions. (B) Teaching kitchens. Participants: (A) Medical trainees. (B) Trainees, providers, and patients. Results: (A) Of the 212 citations identified (N=1,698 trainees), 11 studies met inclusion criteria. The overall effect size was 9.80 (95%CI 7.15-12.456.87-13.85; p<0.001), comparable to the machine learning (ML)-augmented results. The number needed to treat for the top performing high quality study was 12. (B) The hands-on cooking and nutrition education curriculum from the top performing study was applied for medical trainees and providers who subsequently taught patients in the same curriculum (N=5,847). The intervention compared to standard medical care and education alone significantly increased the odds of superior diets (high/medium versus low Mediterranean diet adherence) for residents/fellows most (OR 10.79, 95%CI 4.94-23.58; p<0.001) followed by students (OR 9.62, 95%CI 5.92-15.63; p<0.001), providers (OR 5.19, 95%CI 3.23-8.32, p<0.001), and patients (OR 2.48, 95%CI 1.38-4.45; p=0.002), results consistent with those from ML. Conclusions: This study suggests that medical trainees and providers can improve patients’ diets with nutrition counseling in a manner that is clinically and cost effective and may simultaneously advance societal equity.

scholarly journals Telehealth Use by Age and Race at a Single Academic Medical Center During the COVID-19 Pandemic: Retrospective Cohort Study (Preprint)

2020 ◽  
Author(s):  
Jennifer P Stevens ◽  
Oren Mechanic ◽  
Lawrence Markson ◽  
Ashley O'Donoghue ◽  
Alexa B Kimball
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Health Care Disparities ◽  
Medical Center ◽  
Cohort Analysis ◽  
Academic Medical Center ◽  
Race And Gender ◽  
Asian Patients ◽  
Academic Medical

BACKGROUND During the COVID-19 pandemic, many ambulatory clinics transitioned to telehealth, but it remains unknown how this may have exacerbated inequitable access to care. OBJECTIVE Given the potential barriers faced by different populations, we investigated whether telehealth use is consistent and equitable across age, race, and gender. METHODS Our retrospective cohort study of outpatient visits was conducted between March 2 and June 10, 2020, compared with the same time period in 2019, at a single academic health center in Boston, Massachusetts. Visits were divided into in-person visits and telehealth visits and then compared by racial designation, gender, and age. RESULTS At our academic medical center, using a retrospective cohort analysis of ambulatory care delivered between March 2 and June 10, 2020, we found that over half (57.6%) of all visits were telehealth visits, and both Black and White patients accessed telehealth more than Asian patients. CONCLUSIONS Our findings indicate that the rapid implementation of telehealth does not follow prior patterns of health care disparities.

scholarly journals Oral contraceptive use and cutaneous melanoma risk: a French prospective cohort study

2018 ◽  
Vol 143 (10) ◽  
pp. 2390-2399 ◽  
Author(s):  
I. Cervenka ◽  
Y. Mahamat‐Saleh ◽  
I. Savoye ◽  
L. Dartois ◽  
M.C. Boutron‐Ruault ◽  
...  
Keyword(s):  
Cohort Study ◽  
Oral Contraceptive ◽  
Prospective Cohort Study ◽  
Cutaneous Melanoma ◽  
Prospective Cohort ◽  
Contraceptive Use ◽  
Melanoma Risk ◽  
Oral Contraceptive Use

Analisis Hukum Islam dan Undang-Undang No. 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik terhadap Jual Beli Data Supplier di Agen Fashion

2020 ◽  
pp. 75
Author(s):  
Nur'aeni Nasifah ◽  
Siska Lis Sulistiani ◽  
Yayat Rahmat Hidayat
Keyword(s):  
Data Collection ◽  
Qualitative Method ◽  
Islamic Law ◽  
Descriptive Analysis ◽  
Secondary Data ◽  
Point Of View ◽  
Supplementary Data ◽  
Literature Study ◽  
Face To Face

Abstract. Sale and purchase is transaction that often done by individual or group because there is a transfer of ownership between goods and assets. In practice, sale and purchase is not only done by face to face but also can be done online, as in the case of the sale and purchase of suppliers data at Agen Fashion. This study aims to find out how the transaction practice is and how Islamic law and ITE Law point of view are, whether it is accordance to the laws or not. This research uses qualitative method with normative juridical approach and literature study. The main sources in this study are secondary data that support this research, such as Alquran, Hadith, and the ITE Law. The interviews as data collection techniques are conducted as supplementary data. The analytical method used is descriptive analysis. The results of this study are the transaction is not  accordance with the terms of sale and purchase in Islamic law because there is a lack of clarity (gharar) on the quality of the object and is not accordance as well as the clause no. 9 of the ITE Law because the seller did not explain the object completely.Keywords: Sale and Purchase, Islamic Law, ITE Law, GhararAbstrak. Jual beli merupakan bentuk transaksi yang sering dilakukan oleh tiap individu atau kelompok karena dalam jual beli terdapat perpindahan kepemilikan antara barang dan harta untuk memenuhi kebutuhan hidup. Pada praktiknya, jual beli tidak hanya dilakukan secara bertatap muka melainkan dapat dilakukan secara online, seperti halnya pada jual beli data supplier di Agen Fashion. Penelitian ini bertujuan untuk mengetahui bagaimana praktik jual beli data supplier di Agen Fashion serta bagaimana hukum Islam dan Undang-Undang No. 11 Tahun 2008 Tentang Informasi dan Transaksi Elektronik memandang praktik jual beli data supplier tersebut, apakah telah sesuai dengan hukum yang menjadi pisau analisis dalam penelitian ini atau belum. Penelitian ini menggunakan metode kualitatif dengan pendekatan yuridis normatif dan studi kepustakaan. Sumber utama dalam penelitian ini adalah data sekunder yang mendukung penelitian ini, yaitu Alquran, Hadis, dan UU ITE. Sedangkan teknik pengumpulan data berupa wawancara dilakukan sebagai data pelengkap. Metode analisis yang digunakan yaitu descriptive analysis. Hasil dari penelitian ini adalah transaksi yang terjadi di Agen Fashion tidak sesuai dengan syarat jual beli dalam hukum Islam karena terdapat ketidakjelasan (gharar) pada kualitas objek transaksi, dan tidak sesuai dengan Pasal 9 dalam UU ITE karena pelaku usaha tidak menjelaskan secara lengkap terkait objek yang ditawarkan.Kata Kunci: Jual Beli, Hukum Islam, UU ITE, Gharar

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