Early second trimester maternal plasma levels of thrombin-inhibitor complexes and subsequent spontaneous preterm delivery

2012 ◽  
Vol 32 (12) ◽  
pp. 1170-1173
Author(s):  
Da Eun Lee ◽  
So Yeon Park ◽  
June Seek Choi ◽  
Shin Young Kim ◽  
Ji Hyae Lim ◽  
...  
Keyword(s):  
Preterm Delivery ◽  
Plasma Levels ◽  
Maternal Plasma ◽  
Thrombin Inhibitor ◽  
Second Trimester ◽  
Spontaneous Preterm Delivery

scholarly journals OC17.01: Risk assessment for early spontaneous preterm delivery combining markers from the first and second trimester of pregnancy

2010 ◽  
Vol 36 (S1) ◽  
pp. 32-32
Author(s):  
M. Parra-Cordero ◽  
D. Pedraza ◽  
G. Rencoret ◽  
H. Muñoz ◽  
R. Terra ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Preterm Delivery ◽  
Second Trimester ◽  
Spontaneous Preterm Delivery

Associations between second-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-α and spontaneous preterm delivery in singleton pregnancies

2019 ◽  
Vol 47 (3) ◽  
pp. 304-310 ◽  
Author(s):  
Rauf Melekoglu ◽  
Ercan Yilmaz ◽  
Osman Ciftci ◽  
Yusuf Taner Kafadar ◽  
Ebru Celik
Keyword(s):  
Preterm Birth ◽  
Amniotic Fluid ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Control Group ◽  
Second Trimester ◽  
Spontaneous Preterm Delivery ◽  
Tnf Α ◽  
Factor Α ◽  
Fluid Levels

Abstract Background We investigated the roles of inflammatory cytokines and the A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) family in the etiopathogenesis of spontaneous preterm delivery by comparing the ADAMTS4, ADAMTS5, interleukin (IL)-6, and tumor necrosis factor-α (TNF-α) levels in second-trimester amniotic fluid between pregnant women with preterm birth and term controls. Methods All pregnant women who underwent second-trimester amniocentesis for genetic analysis between January 1, 2016, and January 1, 2018, were enrolled in this study. From this cohort, 22 patients who subsequently experienced spontaneous preterm delivery before 34 weeks of pregnancy formed the study group, and 22 age- and body mass index (BMI)-matched patients without preterm birth constituted the control group. Results No significant differences were observed between the preterm birth and control groups in terms of age, BMI, obstetric history of preterm delivery, gestational age at amniocentesis, or indication for amniocentesis. The mean amniotic fluid levels of ADAMTS4 and ADAMTS5 were significantly increased in the preterm birth group compared to the control group (248.3±22.6 and 182.4±19.8 pg/mL, P=0.012; and 198.6±21.6 and 159.1±21.7 pg/mL, P=0.035, respectively). Significantly increased IL-6 and TNF-α levels were also detected in the amniotic fluid of women who experienced spontaneous preterm delivery, relative to controls (142.1±16.2 and 95.8±16.4 pg/mL, P<0.001; and 139.4±12.5 and 89.6±11.2 pg/mL, P<0.001, respectively). Conclusion The results of this study imply that increased mid-trimester amniotic fluid levels of ADAMTS4, ADAMTS5, IL-6, and TNF-α play an important role in the pathophysiology of spontaneous preterm delivery.

Second-trimester uterine artery Doppler and spontaneous preterm delivery

2004 ◽  
Vol 24 (4) ◽  
pp. 435-439 ◽  
Author(s):  
F. Cobian-Sanchez ◽  
F. Prefumo ◽  
A. Bhide ◽  
B. Thilaganathan
Keyword(s):  
Preterm Delivery ◽  
Uterine Artery ◽  
Second Trimester ◽  
Uterine Artery Doppler ◽  
Spontaneous Preterm Delivery

scholarly journals Second trimester maternal plasma levels of cytokines IL-1Ra, Il-6 and IL-10 and preterm birth

2012 ◽  
Vol 32 (7) ◽  
pp. 483-490 ◽  
Author(s):  
R J Ruiz ◽  
N Jallo ◽  
C Murphey ◽  
C N Marti ◽  
E Godbold ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Plasma Levels ◽  
Maternal Plasma ◽  
Second Trimester

scholarly journals OC15.02: Twin pregnancy: screening test for spontaneous preterm delivery and preeclampsia during the second trimester of pregnancy

2010 ◽  
Vol 36 (S1) ◽  
pp. 29-29
Author(s):  
M. Parra-Cordero ◽  
M. Rodríguez ◽  
R. Díaz ◽  
G. Rencoret ◽  
E. Valdés ◽  
...  
Keyword(s):  
Preterm Delivery ◽  
Screening Test ◽  
Twin Pregnancy ◽  
Second Trimester ◽  
Spontaneous Preterm Delivery

scholarly journals Fetal fraction of cell‐free DNA in maternal plasma in the prediction of spontaneous preterm delivery

2014 ◽  
Vol 45 (1) ◽  
pp. 101-105 ◽  
Author(s):  
M. S. Quezada ◽  
C. Francisco ◽  
D. Dumitrascu‐Biris ◽  
K. H. Nicolaides ◽  
L. C. Poon
Keyword(s):  
Preterm Delivery ◽  
Maternal Plasma ◽  
Cell Free Dna ◽  
Spontaneous Preterm Delivery ◽  
Free Dna ◽  
Fetal Fraction
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