A re-evaluation of the influence of maternal insulin-dependent diabetes on fetal nuchal translucency thickness and first-trimester maternal serum biochemical markers of aneuploidy

2010 ◽  
Vol 30 (10) ◽  
pp. 937-940 ◽  
Author(s):  
K. Spencer ◽  
N. J. Cowans ◽  
C. E. Spencer ◽  
N. Achillea
Keyword(s):  
Biochemical Markers ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Maternal Serum ◽  
Insulin Dependent Diabetes ◽  
Insulin Dependent ◽  
Serum Biochemical

scholarly journals Maternal serum biochemical markers combined with ultrasound diagnosis at the end of the first trimester

2021 ◽  
Vol 26 (4) ◽  
pp. 2879-2884
Author(s):  
MARIUS CRISTIAN MARINAȘ ◽  
LUCIAN GEORGE ZORILĂ ◽  
CIPRIAN LAURENȚIU PĂTRU ◽  
TIBERIU ȘTEFĂNIȚĂ ȚENEA COJAN ◽  
VLAD DUMITRU BALEANU ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
Protein A ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Maternal Serum ◽  
Early Screening ◽  
Crown Rump Length ◽  
Chamber View ◽  
Great Vessel Anomalies ◽  
Serum Biochemical

Objectives. Evaluating the benefits of an early screening of combined maternal markers and ultrasound of the fetuses. Methods. Prospective study (1 January and 31 December 2018) enrolled 187 patients, evaluated at the end of the first trimester of pregnancy (nuchal scan). Biochemical markers: detection of free β human chorionic gonadotropin and serum pregnancy associated plasma protein A. The first trimester ultrasound examination included the assessment of the nuchal translucency, fetal crown rump length and fetal heart. Results. 9 cases with abnormal biomarkers, increased nuchal translucency and cardiac anomalies, including abnormal 4-chamber view (6 cases) and great vessel anomalies (3 cases). 1 case considered initially negative in the first trimester was diagnosed by morphological scan with tetralogy of Fallot in the second trimester. Conclusions. A first trimester combined ultrasound protocol and maternal serum biochemical markers is important in the early prenatal care screening.

Distinctive pattern of first trimester maternal serum biochemical markers in trisomy 22 pregnancies

2008 ◽  
Vol 28 (12) ◽  
pp. 1174-1176 ◽  
Author(s):  
S. Sifakis ◽  
M. Karkaletsi ◽  
S. Christopoulou ◽  
J. Donoghue ◽  
P. Kaminopetros ◽  
...  
Keyword(s):  
Biochemical Markers ◽  
First Trimester ◽  
Maternal Serum ◽  
Distinctive Pattern ◽  
Serum Biochemical

scholarly journals Understanding Biochemical Markers for Antenatal Screening

2010 ◽  
Vol 4 (4) ◽  
pp. 333-335
Keyword(s):  
Biochemical Markers ◽  
First Trimester ◽  
Maternal Serum ◽  
Molecular Techniques ◽  
Screening Tests ◽  
Maternal Circulation ◽  
Beta Hcg ◽  
Increased Risk ◽  
Cell Free Fetal Dna ◽  
Serum Biochemical

ABSTRACT Screening tests to identify fetuses at risk for aneuploidies should be offered to all pregnant women. It should be remembered that screening tests can not diagnose a birth defect; they can only indicate an increased risk. An abnormal screening test result simply mean that additional testing is recommended. Maternal serum biochemical markers in first trimester are free beta-hCG and PAPP-A. In second trimester the markers are AFP, UE3, hCG (Triple test) and inhibin added to these three markers forming the quadruple test. Level of cell free fetal DNA and fetal cells in maternal circulation are some of the molecular techniques for prenatal diagnosis of aneuploidies.

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