Intra- and interobserver reproducibility study of early fetal growth parameters

2008 ◽  
Vol 28 (4) ◽  
pp. 323-331 ◽  
Author(s):  
Bero O. Verburg ◽  
Paul G. H. Mulder ◽  
Albert Hofman ◽  
Vincent W. V. Jaddoe ◽  
Jacqueline C. M. Witteman ◽  
...  
Author(s):  
Shalin A. Parekh ◽  
Stephany M. Cox ◽  
A. James Barkovich ◽  
Vann Chau ◽  
Martina A. Steurer ◽  
...  

AbstractPoor and asymmetric fetal growth have been associated with neonatal brain injury (BI) and worse neurodevelopmental outcomes (NDO) in the growth-restricted population due to placental insufficiency. We tested the hypothesis that postnatal markers of fetal growth (birthweight (BW), head circumference (HC), and head to body symmetry) are associated with preoperative white matter injury (WMI) and NDO in infants with single ventricle physiology (SVP) and d-transposition of great arteries (TGA). 173 term newborns (106 TGA; 67 SVP) at two sites had pre-operative brain MRI to assess for WMI and measures of microstructural brain development. NDO was assessed at 30 months with the Bayley Scale of Infant Development-II (n = 69). We tested the association between growth parameters at birth with the primary outcome of WMI on the pre-operative brain MRI. Secondary outcomes included measures of NDO. Newborns with TGA were more likely to have growth asymmetry with smaller heads relative to weight while SVP newborns were symmetrically small. There was no association between BW, HC or asymmetry and WMI on preoperative brain MRI or with measures of microstructural brain development. Similarly, growth parameters at birth were not associated with NDO at 30 months. In a multivariable model only cardiac lesion and site were associated with NDO. Unlike other high-risk infant populations, postnatal markers of fetal growth including head to body asymmetry that is common in TGA is not associated with brain injury or NDO. Lesion type appears to play a more important role in NDO in CHD.


2020 ◽  
Vol 9 (3) ◽  
pp. 116-125 ◽  
Author(s):  
Daniel F.I. Kurtycz ◽  
Ester Diana Rossi ◽  
Zubair Baloch ◽  
Derek Pavelec ◽  
Emilio Madrigal ◽  
...  

2019 ◽  
Vol 38 (4) ◽  
pp. 613-620
Author(s):  
Francesca Parisi ◽  
Melek Rousian ◽  
Anton H.J. Koning ◽  
Sten P. Willemsen ◽  
Eric A.P. Steegers ◽  
...  

2020 ◽  
pp. 026988112094091
Author(s):  
Eline MP Poels ◽  
Karin Sterrenburg ◽  
André I Wierdsma ◽  
Richard Wesseloo ◽  
Annemerle Beerthuizen ◽  
...  

Background: Lithium is an effective treatment in pregnancy and postpartum for the prevention of relapse in bipolar disorder, but there is a lack of knowledge about the potential adverse impact on fetal development. Aims: To investigate the impact of lithium exposure on early fetal growth. Methods: In this retrospective observational cohort study, we included all singleton pregnancies of women using lithium and referred for advanced fetal ultrasound scanning between 1994 and 2018 to the University Medical Centers in Leiden and Rotterdam, the Netherlands ( n=119). The Generation R study, a population-based cohort, served as a non-exposed control population from the same geographic region ( n=8184). Fetal head circumference, abdominal circumference, femur length, and transcerebellar diameter were measured by ultrasound at 18–22 weeks of gestation. Results: Lithium use during pregnancy was associated with an average increase in head circumference of 1.77 mm (95% confidence interval: 0.53, 3.01), in abdominal circumference of 5.54 mm (95% confidence interval: 3.95, 7.12) and in femur length of 0.59 mm (95% confidence interval: 0.22, 0.96) at 18–22 weeks gestation. Furthermore, lithium use during pregnancy was associated with an average increase in birth weight of 142.43 grams (95% confidence interval: 58.01, 226.89), whereas it was associated with an average decrease of 1.41 weeks in gestational duration (95% confidence interval: −1.78, −1.05). Conclusions: Lithium use during pregnancy was associated with increased fetal growth parameters at 18–22 weeks gestational age and increased birth weight. Further research is needed to evaluate both short- and long-term implications, as well as the mechanisms driving this difference in growth.


Cancer ◽  
2006 ◽  
Vol 111 (1) ◽  
pp. 15-25 ◽  
Author(s):  
Mark E. Sherman ◽  
Abhijit Dasgupta ◽  
Mark Schiffman ◽  
Ritu Nayar ◽  
Diane Solomon

PLoS ONE ◽  
2014 ◽  
Vol 9 (2) ◽  
pp. e87430 ◽  
Author(s):  
Yujing Huang ◽  
Junnan Li ◽  
Jose M. Garcia ◽  
Hui Lin ◽  
Yanzhou Wang ◽  
...  

2015 ◽  
Vol 4 (6) ◽  
pp. S31
Author(s):  
Daniel Kurtycz ◽  
Paul Staats ◽  
Deborah Chute ◽  
Donna Russell ◽  
Maria Friedlander ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document