Tumors of the central nervous system in the first year of life

2007 ◽  
Vol 49 (S7) ◽  
pp. 1074-1082 ◽  
Author(s):  
Valerie Larouche ◽  
Annie Huang ◽  
Ute Bartels ◽  
Eric Bouffet
1977 ◽  
Vol 86 (5) ◽  
pp. 603-610 ◽  
Author(s):  
Timothy J. Reichert ◽  
Charles D. Bluestone ◽  
William K. Sieber ◽  
Sylvan E. Stool ◽  
Anne M. Sieber

Fifteen infants with congenital cricopharyngeal achalasia are reviewed. Although most of the patients had symptoms at birth, the diagnosis was frequently not confirmed until later in the first year of life. While four of the infants had only cricopharyngeal achalasia, 11 had associated diseases related to the central nervous system. Those patients without associated diseases improved spontaneously with conservative management; most of the infants with other abnormalities also improved, although their clinical progress was slower and more complicated. In three of the patients, the symptoms were persistent and there were two deaths related to associated diseases. Cricopharyngeal myotomy was performed on two children with only moderate improvement in symptoms. Congenital cricopharyngeal achalasia is more common than formerly recognized. When suspected, an esophagram with tele- or cineradiography is essential to confirm the diagnosis. Esophageal motility studies will quantify changes and also evaluate lower esophageal dysfunction not easily identified on esophagrams.


1996 ◽  
Vol 42 (1) ◽  
pp. 9-11
Author(s):  
A. A. Afonin ◽  
V. I. Orlov ◽  
Yu. A. Knyazev ◽  
E. P. Rymanhevskaya ◽  
L. A. Polschikova ◽  
...  

A total of 143 children born to mothers who suffered from various forms of endocrine sterility and in whom pregnancy was induced were examined. The levels of somatotropic hormone, prolactin, luteotropic hormone, and follicle-stimulating hormone were measured in the blood on days 1, 3, 6 of life and at the age of 3, 6, and 12 months. The hormones were radioimmunoassayed and measured by imnmnofluorescent methods. The results indicate marked disorders of the adenohypophyseal function in these children, these disorders persisting through the first year of life. The most evident shifts of hormonal parameters are observed in children born to mothers with primary disorders of ovarian hormonal function, particularly so in cases with the polycystic ovaries syndrome, and in children with perinatal involvement of the central nervous system. A high correlation between adenohypophyseal and peripheral gland hormone levels and the concentration of somatotropic hormone was detected.


1963 ◽  
Vol 12 (3) ◽  
pp. 276-290
Author(s):  
L. Maggiore

SUMMARYThe statistical data on the malformation occurred in Italy from 1956 to 1958 have been examined. It has been seen that their number is almost constant (i. e. some 1,500 per year). The ratio of alive malformed to dead malformed is of 3:1, but the number of deaths by congenital malformations increases considerably during the first year of life, mostly due to inner organ malformations, non detectable at birth.50% of the cases of harelip die during the first year of life. The most serious malformations are those concerning the central nervous system, while the most common ones, are those affecting the locomotive apparatus.The number of malformations has not been influenced by the very insufficient diet during the four years of war, neither by the 1957 « asiatic influenza ». The malformation index, furthermore, appears almost constant in the time and in the various regions, showing the highest figure in Lucania and Friuli (3.05) and the lowest ones in Campania (0,89), Sicily and Liguria (1.21).


Author(s):  
V. A. Zhelev ◽  
A. S. Pogudina ◽  
E. V. Mikhalev ◽  
A. O. Okorokov ◽  
T. S. Krivonogova ◽  
...  

Aim. To study the features of recovery period of hypoxic lesion to the central nervous system (CNS) in children of the first year of life in the presence of congenital heart disease (CHD).Material and Methods. The study involved 80 children born full-term and premature with gestational status of 35–37 weeks with hypoxic damage to the CNS. The main observation group comprised 50 children with CHD (interventricular and atrial septal defects, open ductus arteriosus). All children underwent a comprehensive health assessment, standard echocardiography, and neurosonography at ages of five to seven days and one, three, and six months. Biochemical analysis included assessment of serum neurospecific enolase (NSE), succinate dehydrogenase (SDG), and α-glycerophosphate dehydrogenase (α-GPDH). The control group included 20 full-term newborns without CHD and CNS lesions.Results. The main manifestations in newborns with CHD and hypoxic damage to the CNS were the suppression syndrome, agitation, and hypertension-hydrocephalic syndrome. At the age of six months, a delay in motor development indicators persisted in 35% of children in the main group. The high NSE level in newborns with concomitant septal heart defects was associated with a decrease in the quantitative indicators of neuropsychic development (g = –0.6, p < 0.05). The children with CHD and hypoxic damage to the CNS in the first year of life were significantly more often (p < 0.05) deficient in weight and height. A decrease in the resistance level in the first year of life was observed in 40% of children from the main group, which significantly differed compared with group of children without CHD (p < 0.001). The newborns with hypoxic CNS and CHD lesions had a decrease in the activity of α-GPDH and SDG at the age of five to seven days; the low activity of SDG persisted at the ages of one and six months; the enzyme activity in children of the comparison group was normal (p < 0.05).Conclusion. Children with CHD had the features of clinical course of perinatal damage to the CNS in the acute and recovery periods, a slowdown in the rate of physical and neuropsychic development, a decrease in the resistance level, and impaired functional state of the body. The decreases in the activities of SDG and α-GPDH in children with hypoxic lesions to the CNS in the presence of CHD implied the disturbances in cellular bioenergetics and resulted in inadequate response to external factors.


2020 ◽  
Vol 3 (6) ◽  
pp. 26-27
Author(s):  
Yo. K. Eronov

Cerebral palsy, one of the diseases of the central nervous system, is a serious disease that is caused by various brain injuries during the first year of life: before, inside and after childbirth. Patients with cerebral palsy lag behind in physical and mental development, and due to their inability to help themselves, this causes not only medical, but also social problems. Proper dental care for sick children with cerebral palsy is one of the measures to prevent diseases of the oral mucosa and its complications


2019 ◽  
Vol 12 (3) ◽  
pp. 72-82
Author(s):  
Victor Petrovich Maltsev ◽  
Zhanar Tuleutayevna Suyundikova

Aim. The Federal State Educational Standard of Higher Education prescribes providing the educational process in accordance with the individual and typological features of students. The nature of adaptation shifts in students depends on ethnic, ecological, and morphological indicators determining the functional status of the body. Its functional status and functional abilities conditioned by academic and professional activities are determined by the cerebral process, which influences the efficiency of adaptation and cognitive performance in general. The article deals with studying the features of psychophysiological potential in Russian and Kazakh first-year female students during their adaptation to studying at the pedagogical university. Materials and methods. We conducted the diagnostics of the functional status of the central nervous system and cognitive performance in first-year female students at pedagogical universities. The average age of participants was 17.9 years. The total sample (n = 120) consisted of the Russian and Kazakh students living in Kostanay (Kazakhstan) and Chelyabinsk (Russia). A simple eye motor response (SEMR) and a complex eye motor response (CEMR) to a light stimulus were measured with the NS-Psychotest equipment. The calculated data are the following: the functional status of the system; response stability; level of functional abilities. These data were used as a basis for the assessment of cognitive performance in the participants of the study. Results. The results obtained characterize the neuro-dynamic basis of first-year students’ adaptation expressed in the average level of CNS activity, mobility of nervous processes, and optimal functional abilities. In the conditions of the average intragroup expression of the functional criteria of the central nervous system better cognitive processes for the processing of sensory information were revealed in students from Chelyabinsk compared to Kostanay. Conclusion. The analysis of the data obtained revealed the regional specifics of the average values of chronoreflexometry in first-year students, namely a significantly higher level of neural interaction and sensorimotor processing in first-year students from Chelyabinsk.


Author(s):  
A. I. Safina ◽  
E. V. Volyanyuk ◽  
M. V. Potapova ◽  
T. S. Fisheleva

The article presents the analysis of the health status of children born prematurely during the first year of their life. There is the comparison of morbidity rates for five years of the operation of the catamnesis center of Kazan. Profoundly premature children demonstrated the highest level of morbidity with more frequent pathologies of the central nervous system, respiratory organs, eyes and anemia of premature children. In 2017 there was a decrease in the frequency and severity of respiratory diseases (bronchopulmonary dysplasia with chronic respiratory insufficiency 1.6 times), the nervous system (severe ischemic and hypoxic-hemorrhagic lesions of CNS 2.7 times), eyes and its adnexa (a complicated retinopathy of premature children 1.7 times) in extremely premature infants.


2016 ◽  
Vol 50 (1) ◽  
pp. 11
Author(s):  
Dedy Rahmat ◽  
Irawan Mangunatmadja ◽  
Bambang Tridjaja ◽  
Taralan Tambunan ◽  
Rulina Suradi

Background Epilepsy in cerebral palsy (CP) is usually difficult to treat and can lead to poor prognosis due to increased risk for motor and cognitive disorders. The prevalence and risk factors of epilepsy in children with CP vary among studies.Objective To determine the prevalence and risk factors for epilepsy in spastic CP.Methods We performed a retrospective study using medical records of patients with spastic CP at the Departement of Child Health, Cipto Mangunkusumo Hospital from January 2003 until December 2008. Prevalence ratio was calculated by comparing the prevalence of epilepsy in subjects with and without risk factors. We excluded patients with metabolic disorder, genetic syndrome, and onset of CP after 3 years of age.Results Two hundred thirty six out of 238 spastic CP patients were analyzed. The mean age at diagnosis of spastic CP was 28.8 months. Male to female ratio was 1.4:1. The prevalence of epilepsy in spastic CP was 39%. The risk factors for epilepsy in spastic CP were central nervous system infection, the ocurrence of seizure in the first year of life, and abnormality of EE G.Conclusions The prevalence of epilepsy in spastic CP is 39%. The risk factors for epilepsy in spastic CP are post central nervous system infection, and ocurrence of seizure in the first year of life. [Paediatr Indones. 2010;50:11-7].


2008 ◽  
Vol 7 (2) ◽  
pp. 112-114
Author(s):  
L. V. Kapilevich ◽  
Ye. V. Zamoulina

Decreased amplitude and increased latency of visual and cognitive excited potentials were revealed in football-players in the stage of prima ry special sports training in the first year of their training process. In the second training year, this amplitude is increased and latency is decreased. Forming special physical preparing of the football-players in the stage of primary sports specialization is mutually correlated with functional changes in the central nervous system which manifested in decreased latent period and increased amplitude of excited potentials of the brain.


2016 ◽  
Vol 97 (3) ◽  
pp. 341-346
Author(s):  
T F Schreider ◽  
G V Fedorova ◽  
S N Yakimenko

Aim. To study the effectiveness of complex physical rehabilitation use in infants with perinatal central nervous system injury.Methods. A complex examination of children with perinatal central nervous system pathology was performed. Based on identified changes, a method of children complex physical rehabilitation was developed, theoretically proved and tested, including manual relaxing massage and anti-gravity gymnastics. The study included 360 children of the first year of life. Massage was performed starting from 3-4 weeks of a child’s life, the procedure duration was 20-25 minutes. Antigravity gymnastics was performed for 3-4 minutes in children aged 1-2 months, 8-10 min - at the age of 3-4 months, 10-15 minutes - at the age of 5-6 months and older. Course consisted of 15-20 procedures, five times a week.Results.. Effectiveness evaluation was conducted in two ways: objective and subjective. Objectively: the positive dynamics of neurological symptoms was reported, symptoms of brain hypoxia, regulatory systems tension index were significantly decreased, the sleep-wake ratio normalized, weight gain occurred. Subjectively: 360 parents of children up to 1 year were interviewed. 93.6±1.3% of the respondents were satisfied with quality of care. Omsk region inhabitants satisfaction was 95.45±1.1% and was higher than in Omsk (93.5±1.3%, pConclusion. The applied method of complex physical rehabilitation of children of the first year of life with perinatal central nervous system injury showed high efficacy in the absence of side effects and may be reproduced in any institutions where rehabilitation measures are performed.


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