Role of heat treatment in childhood cancers: Distinct resistance profiles of solid tumor cell lines towards combined thermochemotherapy

2005 ◽  
Vol 45 (5) ◽  
pp. 663-669 ◽  
Author(s):  
Anette Debes ◽  
Reinhart Willers ◽  
Ulrich Göbel ◽  
Rüdiger Wessalowski
Keyword(s):  
Heat Treatment ◽  
Tumor Cell ◽  
Cell Lines ◽  
Solid Tumor ◽  
Tumor Cell Lines ◽  
Childhood Cancers

C-prenylated flavonoids with potential cytotoxic activity against solid tumor cell lines

2019 ◽  
Vol 18 (4) ◽  
pp. 1051-1100
Author(s):  
Lenka Molčanová ◽  
Dominika Janošíková ◽  
Stefano Dall´Acqua ◽  
Karel Šmejkal
Keyword(s):  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Solid Tumor ◽  
Tumor Cell Lines ◽  
Prenylated Flavonoids

scholarly journals Silencing of anti-apoptotic transmembrane protein lifeguard sensitizes solid tumor cell lines MCF-7 and SW872 to perifosine-induced cell death activation

2011 ◽  
Vol 2 (3) ◽  
pp. 419-422 ◽  
Author(s):  
VESNA BUCAN ◽  
CLAUDIA Y.U. CHOI ◽  
ANDREA LAZARIDIS ◽  
PETER M. VOGT ◽  
KERSTIN REIMERS
Keyword(s):  
Cell Death ◽  
Tumor Cell ◽  
Cell Lines ◽  
Solid Tumor ◽  
Transmembrane Protein ◽  
Tumor Cell Lines ◽  
Mcf 7

scholarly journals GATA-1 and GATA-2 binding to 3′ enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines

Leukemia ◽  
2009 ◽  
Vol 23 (7) ◽  
pp. 1270-1277 ◽  
Author(s):  
A Furuhata ◽  
M Murakami ◽  
H Ito ◽  
S Gao ◽  
K Yoshida ◽  
...  
Keyword(s):  
Acute Leukemia ◽  
Tumor Cell ◽  
Cell Lines ◽  
Solid Tumor ◽  
Tumor Cell Lines ◽  
Wt1 Gene

Abstract B113: Role of I‐TAC‐binding receptors CXCR3 and CXCR7 in biology of various tumor cell lines

2009 ◽  
Author(s):  
Katarzyna Miekus ◽  
Danuta Jarocha ◽  
Elzbieta Trzyna ◽  
Marcin Majka
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Tumor Cell Lines

260p53 and p16 expression after γ-irradiation and heat treatment in human tumor cell lines

1996 ◽  
Vol 40 ◽  
pp. S68
Author(s):  
M.T. Valenzuela ◽  
M.I. Nuñez ◽  
M. Villalobos ◽  
M.R. Guerrero ◽  
V. Pedraza ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Tumor Cell ◽  
Cell Lines ◽  
Human Tumor ◽  
Tumor Cell Lines ◽  
Human Tumor Cell ◽  
Γ Irradiation ◽  
Human Tumor Cell Lines ◽  
P16 Expression

Antiproliferative activity of novel benzo[b][1,6]naphthyridines in human solid tumor cell lines

2010 ◽  
Vol 20 (5) ◽  
pp. 1504-1506 ◽  
Author(s):  
Simonas Rudys ◽  
Carla Ríos-Luci ◽  
Eduardo Pérez-Roth ◽  
Inga Cikotiene ◽  
José M. Padrón
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Solid Tumor ◽  
Antiproliferative Activity ◽  
Tumor Cell Lines ◽  
Human Solid Tumor

scholarly journals Lipophilic Salirasib analogs with enhanced antiproliferative activity against human solid tumor cell lines

2021 ◽  
Author(s):  
Exequiel O. J. Porta ◽  
María Sol Ballari ◽  
José M. Padrón ◽  
Guillermo R. Labadie
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Cancer Cell ◽  
Solid Tumor ◽  
Antiproliferative Activity ◽  
In Silico ◽  
Tumor Cell Lines ◽  
Human Solid Tumor ◽  
Physicochemical Features ◽  
Sar Analysis

Aim: We proposed to determine the antiproliferative activity of a series of synthetic salirasib analogs, presenting or not a 1,2,3-triazole linker, against five different cancer cell lines. Results: Bioassay, cheminformatic, and in silico ADME-Tox allowed the identification of new potent analogs. SAR analysis allowed the identification of structural and physicochemical features that benefit the antiproliferative activity. Conclusion: Isoprenyl R chains with three or more isoprene units, or long aliphatic R chains are the preferred ones within the active compounds. Likewise, we have identified three compounds with better activity profiles than salirasib against all the cell lines tested.

scholarly journals Cyclamen Exerts Cytotoxicity in Solid Tumor Cell Lines: a Step Toward New Anticancer Agents?

2013 ◽  
Vol 14 (10) ◽  
pp. 5911-5913 ◽  
Author(s):  
Mustafa Yildiz ◽  
Hakan Bozcu ◽  
Onur Tokgun ◽  
Ege Riza Karagur ◽  
Oktay Akyurt ◽  
...  
Keyword(s):  
Tumor Cell ◽  
Cell Lines ◽  
Solid Tumor ◽  
Anticancer Agents ◽  
Tumor Cell Lines

scholarly journals The ability to overcome multidrug resistance of tumor cell lines by novel acridine cytostatics with condensed heterocyclic rings.

2002 ◽  
Vol 49 (1) ◽  
pp. 87-92 ◽  
Author(s):  
Maria M Bontemps-Gracz ◽  
Agnieszka Kupiec ◽  
Ippolito Antonini ◽  
Edward Borowski
Keyword(s):  
Multidrug Resistance ◽  
Tumor Cell ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Human Tumor ◽  
Heterocyclic Ring ◽  
Tumor Cell Lines ◽  
Human Tumor Cell Lines

Two recently synthesized groups of acridine cytostatics containing fused heterocyclic ring(s): pyrazoloacridines (PAC) and pyrazolopyrimidoacridines (PPAC) were tested in regard to their in vitro cytotoxic activity towards a panel of sensitive and resistant human tumor cell lines. The obtained results corroborate our earlier hypothesis on the essential role of heterocyclic ring fused to the acridine moiety in the ability of acridine cytostatics to overcome multidrug resistance of tumor cells. The presence, location and kind of substituents considerably influenced both the cytotoxic activity of the derivatives and their ability to overcome multidrug resistance. The same factors also affected the cytostatics ability to differentiate between tumor cell lines with various types of drug exporting pumps.

Sign in / Sign up

Export Citation Format

Share Document