Prophylaxis of acute chemotherapy-induced nausea and vomiting in children with cancer: What is the evidence?

2004 ◽  
Vol 43 (6) ◽  
pp. 651-658 ◽  
Author(s):  
Emmanuel S. Antonarakis ◽  
Jamie L. Evans ◽  
Gemma F. Heard ◽  
Lucy M. Noonan ◽  
Barry L. Pizer ◽  
...  
Keyword(s):  
Nausea And Vomiting ◽  
Children With Cancer

scholarly journals Systematic review of the effectiveness of complementary and alternative medicine on nausea and vomiting in children with cancer: a study protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. e031834
Author(s):  
Ka Yan Ho ◽  
Katherine Ka Wai Lam ◽  
Joyce Oi Kwan Chung ◽  
Wei Xia ◽  
Ankie Tan Cheung ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Symptom Burden ◽  
Biomedical Literature ◽  
Nausea And Vomiting ◽  
Controlled Trials ◽  
Cochrane Central Register ◽  
Children With Cancer ◽  
Ethical Approval ◽  
Registration Number ◽  
Randomised Controlled

IntroductionNausea and vomiting are two most common symptoms reported by children with cancer when they undergo active treatment. However, pharmacological treatment is not sufficient to manage these two symptoms, with over 40% of children still experience nausea and vomiting after receiving antiemetics. There has been an exponential growth of studies to demonstrate the effectiveness of different complementary complementary medicine (CAM) to control nausea and vomiting during cancer treatment. Appropriate application of CAM enhances the effectiveness of antiemetics, thus reducing the symptom burden on children as well as improving their general condition and quality of life during cancer treatment. Nevertheless, it remains unclear which CAM is the best approach to help children to prevent or reduce nausea and vomiting during and after cancer treatment. This paper describes a protocol for identifying, analysing and synthesising research evidence on the effectiveness of CAM on nausea and vomiting in children with cancer.Methods and analysisA total of 10 databases will be searched to identify appropriate literature: MEDLINE, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, CINAHL, PsycINFO, LILACS, OpenSIGLE, the Chinese Biomedical Literature Database, the Chinese Medical Current Contents and the Chinese National Knowledge Infrastructure. All randomised controlled trials which meet the inclusion criteria will be included. The primary outcome is the changes in nausea and vomiting either assessed by self-reported and/or objective measures. Review Manager 5.3 will be used to synthesise the data, calculate the treatment effects, perform any subgroup analysis and assess the risk of bias.Ethical and disseminationThe results will be presented at international conferences and published in peer-reviewed journals. As no individual data will be involved in this review, ethical approval is not required.PROSPERO registration numberCRD42019135404.

scholarly journals Guideline for the Treatment of Breakthrough and the Prevention of Refractory Chemotherapy-Induced Nausea and Vomiting in Children With Cancer

2016 ◽  
Vol 63 (7) ◽  
pp. 1144-1151 ◽  
Author(s):  
Jacqueline Flank ◽  
Paula D. Robinson ◽  
Mark Holdsworth ◽  
Robert Phillips ◽  
Carol Portwine ◽  
...  
Keyword(s):  
Nausea And Vomiting ◽  
Children With Cancer

Nausea in Numbers: Electronic Medical Record Nausea and Vomiting Assessment for Children With Cancer

2020 ◽  
Vol 37 (3) ◽  
pp. 195-203
Author(s):  
Anna Evans ◽  
Mary Beth Vingelen ◽  
Candy Yu ◽  
Jennifer Baird ◽  
Paula Murray ◽  
...  
Keyword(s):  
Quality Improvement ◽  
Medical Record ◽  
Electronic Medical Record ◽  
Assessment Tool ◽  
Quality Improvement Project ◽  
Nausea And Vomiting ◽  
Children With Cancer ◽  
Improvement Project ◽  
Patient Reported ◽  
The Impact

Purpose: Chemotherapy-induced nausea and vomiting (CINV) is a distressing, underrecognized effect of treatment that can occur in up to 80% of patients. The purpose of this quality improvement project was to evaluate the impact of implementation of a standardized nausea assessment tool, the Baxter Animated Retching Faces (BARF) scale, on nursing compliance with nausea assessment and the frequency and severity of patient-reported CINV for children with cancer. Method: The Plan-Do-Study-Act cycle was used to implement this practice change. With stakeholder support and hospital governance council approval, the BARF scale was introduced into the electronic medical record. Nurses were provided education about the assessment tool and were given badge buddy cards to prompt use of the tool, and workstation reminders were created. A root cause analysis was conducted to provide feedback for continuous quality improvement. Results: Retrospective, aggregate electronic medical record data from May 2018 to April 2019 were analyzed for assessment compliance, total number of admissions with vomiting episodes, and average BARF score. Over the 12-month implementation period, run charts demonstrated a shift in nursing practice with increased compliance in documented nausea assessments during the second 6-month period. There was not a significant decrease in patient-reported CINV. Conclusion: The use of standardized nausea assessments based on patient self-reporting can provide useful and consistent feedback for nurses and health care providers. This quality improvement project demonstrated increased compliance with nausea assessment documentation. Further studies are needed to demonstrate that improvements in nausea assessment may reduce the frequency and severity of CINV.

scholarly journals pengaruh akupresur titik Nei Guan terhadap mual muntah akibat kemoterapi emetogenik tinggi pada penyandang kanker anak usia sekolah

2019 ◽  
Vol 7 (1) ◽  
Author(s):  
Triliana Purwadesi Yuliar ◽  
Susi Susanah ◽  
Ikeu Nurhidayah
Keyword(s):  
Adjuvant Therapy ◽  
Intervention Group ◽  
Emetogenic Chemotherapy ◽  
Assessment Tools ◽  
Nausea And Vomiting ◽  
School Age Children ◽  
Control Group ◽  
School Age ◽  
Highly Emetogenic Chemotherapy ◽  
Children With Cancer

Chemotherapy as a pediatric cancer treatment has nausea and vomiting side effects. Nausea and vomiting in school-age children with cancer can lead to nutritional, emotional, playing, and school function disorders, decreasing the quality of life in children. An adjuvant therapy that can decrease chemotherapy-induced nausea and vomiting is acupressure which is non-invasive and safe. Nei Guan acupressure point uses pressure technique on the wrist. This study was conducted to determine effects of Nei Guan acupressure on nausea and vomiting due to highly emetogenic chemotherapy in school-age children with cancer. The study design was quasi-experimental through a pre-post test design study approach, with single-blind control. Thirty respondents obtained from the average calculation of two population hypothesis test, were divided into a control and intervention group comprising 15 people respectively. Both groups got the same antiemetic. Measurement of nausea was performed three times during the study using the Pediatric Nausea Assessment Tools (PeNAT), while vomiting intervals were documented for every vomiting and retching. Data analysis used the Mann Whitney and independent t-test. The analysis result in the control group showed that the average nausea value tended to increase and the vomiting interval was faster than in the intervention group. In conclusion, Nei Guan acupressure affects nausea and vomiting due to highly emetogenic chemotherapy in school-aged children with cancer although it is not statistically significant (p-value> 0.05). Nurses are expected to monitor ongoing nausea and vomiting, and consider acupressure as adjuvant therapy, besides providing pharmacological treatment to reduce nausea and vomiting.

Pharmacological Management of Chemotherapy-Induced Nausea and Vomiting in Children with Cancer

2009 ◽  
Vol 21 (6) ◽  
pp. 605-610 ◽  
Author(s):  
M.G. Cefalo ◽  
A. Ruggiero ◽  
P. Maurizi ◽  
G. Attinà ◽  
A. Arlotta ◽  
...  
Keyword(s):  
Nausea And Vomiting ◽  
Children With Cancer ◽  
Pharmacological Management

The Role of Clinical Guidelines for the Management of Chemotherapy-Induced Nausea and Vomiting in Children with Cancer

2022 ◽  
Author(s):  
Hamid Farhangi ◽  
Ali Ghasemi ◽  
Mojgan Bahari ◽  
Zohreh Alirezaei ◽  
Akram Rabbani Javadi ◽  
...  
Keyword(s):  
Clinical Guidelines ◽  
Nausea And Vomiting ◽  
Control Group ◽  
Children With Cancer ◽  
Protocol Group ◽  
Quasi Experimental ◽  
Pediatric Oncology Group ◽  
The Mean

Background: Nausea and vomiting are among the most important side-effects associated with chemotherapy in children with cancer, affecting the quality of their lives. Clinical guidelines for selecting antiemetics are effective in reducing acute chemotherapy-induced nausea and vomiting (CINV). Materials and Methods: The present quasi-experimental study compared the effectiveness of the Pediatric Oncology Group of Ontario (POGO) CINV guideline with that of conventional arbitrary therapies for CINV in 82 children aged 6 months to 16 years old. Out of 177 cycles of chemotherapy, in 101 cycles patients were treated according to POGO-CINV Guideline; in the other 76 cycles, patients were treated with arbitrary types and doses of antiemetics. Then, vomiting in the first 24 hours after chemotherapy in both groups was measured and compared. Results: In this study, 82 patients hospitalized in the Hematology Department of Dr. Sheikh Children’s Hospital were enrolled, of whom 48 patients (58.7%) were boys and 34 (41.3%) were girls. The mean age of patients was 6.24±4.47 years (6 months to 16 years). The results of the current study showed that using a protocol for the prevention of vomiting based on the patient’s age and the type of chemotherapy is superior to conventional management of CINV. Findings showed that the frequency of nausea and vomiting in the protocol group was significantly reduced in comparison with the control group (p˂0.005). Moreover, a reduction in the frequency of nausea and vomiting was quite significant in the sub-categories of the protocol group who had received high-risk or moderate-risk emetogenic drugs (p˂0.005). Conclusion: The results of the current study showed that using the POGO guideline, which takes into account the patient’s age and the type of chemotherapy, is more effective than arbitrary management of CINV, particularly in children.

Hypnotherapy for control of anticipatory nausea and vomiting in children with cancer: Preliminary findings

1995 ◽  
Vol 4 (2) ◽  
pp. 101-106 ◽  
Author(s):  
P. J. Hawkins ◽  
C. Liossi ◽  
B. W. Ewart ◽  
P. Hatira ◽  
V. H. Kosmidis ◽  
...  
Keyword(s):  
Nausea And Vomiting ◽  
Anticipatory Nausea ◽  
Children With Cancer ◽  
Anticipatory Nausea And Vomiting
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