scholarly journals Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications

2018 ◽  
Vol 247 (2) ◽  
pp. 214-227 ◽  
Author(s):  
Amy Ellen McCart Reed ◽  
Emarene Kalaw ◽  
Katia Nones ◽  
Mark Bettington ◽  
Malcolm Lim ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Molecular Dissection ◽  
Metaplastic Breast Cancer ◽  
Prognostic Implications

Clinicopathological and Imaging Features Predictive of Clinical Outcome in Metaplastic Breast Cancer

2020 ◽  
Vol 16 (6) ◽  
pp. 729-738
Author(s):  
Ga Young Yoon ◽  
Joo Hee Cha ◽  
Hak Hee Kim ◽  
Hee Jung Shin ◽  
Eun Young Chae ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinical Outcome ◽  
Clinical Outcomes ◽  
Tumor Size ◽  
Multivariable Analysis ◽  
Disease Free Survival ◽  
Imaging Features ◽  
Peritumoral Edema ◽  
Imaging Findings ◽  
Metaplastic Breast Cancer

Background: Metaplastic breast cancer (MC) is a rare disease, thus it is difficult to study its clinical outcomes. Objective: To investigate whether any clinicopathological or imaging features were associated with clinical outcome in MC. Methods: We retrospectively evaluated the clinicopathological and imaging findings, and the clinical outcomes of seventy-two pathologically confirmed MCs. We then compared these parameters between triple-negative (TNMC) and non-TNMCs (NTNMC). Results: Oval or round shape, and not-circumscribed margin were the most common findings on mammography, ultrasound (US), and magnetic resonance imaging (MRI). It was mostly a mass without calcification on mammography, and revealed complex or hypoechoic echotexture, and posterior acoustic enhancement on US, and rim enhancement, wash-out kinetics, peritumoral edema, and intratumoral necrosis on MRI. Of all 72, 64 were TNMCs, and eight were NTNMCs. Clinicopathological and imaging findings were similar between the two groups, except that MRI showed peritumoral edema more frequently in TNMCs than NTNMCs (p=0.045). There were 21 recurrences and 13 deaths. Multivariable analysis showed that larger tumor size and co-existing DCIS were significantly predictive of Disease free survival (DFS), and larger tumor size and neoadjuvant chemotherapy were significantly predictive of overall survival (OS). Conclusion: MC showed characteristic imaging findings, and some variables associated with survival outcome may help to predict prognosis.

Lymphatic and angiogenic characteristics in breast cancer: morphometric analysis and prognostic implications

2008 ◽  
Vol 113 (2) ◽  
pp. 261-273 ◽  
Author(s):  
Rabab A. A. Mohammed ◽  
Ian O. Ellis ◽  
Somaia Elsheikh ◽  
Emma C. Paish ◽  
Stewart G. Martin
Keyword(s):  
Breast Cancer ◽  
Morphometric Analysis ◽  
Prognostic Implications

scholarly journals Right Breast Metaplastic Carcinoma with Chondroid Diff erentiation (Chondrosarcoma)

2018 ◽  
Vol 22 (4) ◽  
pp. 45-51
Author(s):  
Alya S. Binmahfouz
Keyword(s):  
Breast Cancer ◽  
Metaplastic Carcinoma ◽  
Adjuvant Radiation ◽  
Resonance Imaging ◽  
Metaplastic Breast Cancer ◽  
Diagnostic Features ◽  
Palpable Mass ◽  
Adjuvant Radiation Therapy ◽  
The Right ◽  
Metaplastic Breast Carcinoma

Metaplastic breast cancer is rare, representing < 5% of breast cancer (only eight cases have been reported so far). We present here a 42-year-old female complaining of a painless lump in the right breast for the previous two months. Physical examination revealed a palpable mass. Lumpectomy was performed and histopathologic examination revealed metaplastic breast carcinoma with foci of chondrosarcoma. The patient received adjuvant radiation therapy and chemotherapy and is currently following up as an outpatient. We also discuss diff erentimaging diagnostic features of this specifi c type of breast cancer using mammography, ultrasonography, and magnetic resonance imaging.

scholarly journals Correction to: Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer

2018 ◽  
Vol 167 (2) ◽  
pp. 605-606
Author(s):  
Muhammad Asaduzzaman ◽  
Stephanie Constantinou ◽  
Haoxiang Min ◽  
John Gallon ◽  
Meng-Lay Lin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Tumour Suppressor ◽  
Paclitaxel Resistance ◽  
Metaplastic Breast Cancer

Prognostic Implications of Immune Infiltrates in the Breast Cancer Microenvironment

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Sidar Bagbudar ◽  
Hasan Karanlik ◽  
Neslihan Cabioglu ◽  
Aysel Bayram ◽  
Kamuran Ibis ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Microenvironment ◽  
Prognostic Implications

AB195. 194. Clinicopathological features and management of metaplastic breast cancer: a single institution experience

2018 ◽  
Vol 2 ◽  
pp. AB195-AB195
Author(s):  
Niamh Siobhan Buckley ◽  
Syer Ree Tee ◽  
Anne O’Doherty ◽  
Cecilly Quinn ◽  
Jane Rothwell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Clinicopathological Features ◽  
Single Institution ◽  
Metaplastic Breast Cancer
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