Epstein-Barr virus in nasal T-cell lymphomas (polymorphic reticulosis/midline malignant reticulosis) in Western China

1994 ◽  
Vol 173 (2) ◽  
pp. 81-87 ◽  
Author(s):  
Joost Van Gorp ◽  
Liu Weiping ◽  
Karen Jacobse ◽  
Liu Yong-Huei ◽  
Li Feng-Yuan ◽  
...  
Blood ◽  
1994 ◽  
Vol 84 (12) ◽  
pp. 4053-4060 ◽  
Author(s):  
K Sandvej ◽  
SC Peh ◽  
BS Andresen ◽  
G Pallesen

In this study, we have sequenced the C-terminal part of the Epstein- Barr virus (EBV)-BNLF-1 gene encoding for the latent membrane protein-1 from tissues of EBV-positive Danish Hodgkin's disease (HD) and of Danish and Malaysian peripheral T-cell lymphomas (PTLs) and from tonsils of Danish infectious mononucleosis (IM). Our study showed that some of the 7 single-base mutations and the 30-bp deletion previously detected between codons of amino acid 322 and 366 in the BNLF-1 gene of the nasopharyngeal carcinoma cell line CAO were present in all Malaysian PTLs and in 60% of the Danish PTLs. In HD and the IM cases, the mutations were present in about 30%. The 30-bp deletion and the single base mutations occurred independently, and mutations were detectable in the majority of EBV type B-positive cases. These findings suggest that the 30-bp deletion and the 7 single-base mutations in the C-terminal part of the CAO-BNLF-1 gene do not characterize a new EBV type A substrain. Rather, some of the positions of single base mutations and the 30-bp deletion are hot spots that may have mutated independently through the evolution of EBV strains.


2011 ◽  
Vol 59 (6) ◽  
pp. 1183-1193 ◽  
Author(s):  
Socorro M Rodríguez-Pinilla ◽  
Carlos Barrionuevo ◽  
Juan García ◽  
María de los Ángeles ◽  
Raquel Pajares ◽  
...  

1998 ◽  
Vol 20 (3) ◽  
pp. 250-254 ◽  
Author(s):  
Yun-Ting Chang ◽  
Han-Nan Liu ◽  
Chang-Lin Chen ◽  
Kuan-Chih Chow

2009 ◽  
Vol 129 (6) ◽  
pp. 1556-1561 ◽  
Author(s):  
Mauro Novelli ◽  
Chiara Merlino ◽  
Renata Ponti ◽  
Massimiliano Bergallo ◽  
Pietro Quaglino ◽  
...  

PLoS ONE ◽  
2011 ◽  
Vol 6 (11) ◽  
pp. e27271 ◽  
Author(s):  
Rajesh Ramakrishnan ◽  
Hart Donahue ◽  
David Garcia ◽  
Jie Tan ◽  
Norio Shimizu ◽  
...  

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