Epstein-Barr virus characteristics and its correlation with the expression of cytotoxic proteins and cytokines in non-nasal peripheral T-cell lymphomas

1999 ◽  
Author(s):  
Wen-ying Ho
Keyword(s):  
T Cell ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Cytotoxic Proteins ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas

scholarly journals Identification of potential hot spots in the carboxy-terminal part of the Epstein-Barr virus (EBV) BNLF-1 gene in both malignant and benign EBV-associated diseases: high frequency of a 30-bp deletion in Malaysian and Danish peripheral T-cell lymphomas

Blood ◽  
1994 ◽  
Vol 84 (12) ◽  
pp. 4053-4060 ◽  
Author(s):  
K Sandvej ◽  
SC Peh ◽  
BS Andresen ◽  
G Pallesen
Keyword(s):  
T Cell ◽  
Hot Spots ◽  
Epstein Barr Virus ◽  
Terminal Part ◽  
Gene Encoding ◽  
Single Base ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas

In this study, we have sequenced the C-terminal part of the Epstein- Barr virus (EBV)-BNLF-1 gene encoding for the latent membrane protein-1 from tissues of EBV-positive Danish Hodgkin's disease (HD) and of Danish and Malaysian peripheral T-cell lymphomas (PTLs) and from tonsils of Danish infectious mononucleosis (IM). Our study showed that some of the 7 single-base mutations and the 30-bp deletion previously detected between codons of amino acid 322 and 366 in the BNLF-1 gene of the nasopharyngeal carcinoma cell line CAO were present in all Malaysian PTLs and in 60% of the Danish PTLs. In HD and the IM cases, the mutations were present in about 30%. The 30-bp deletion and the single base mutations occurred independently, and mutations were detectable in the majority of EBV type B-positive cases. These findings suggest that the 30-bp deletion and the 7 single-base mutations in the C-terminal part of the CAO-BNLF-1 gene do not characterize a new EBV type A substrain. Rather, some of the positions of single base mutations and the 30-bp deletion are hot spots that may have mutated independently through the evolution of EBV strains.

Elevated plasma Epstein-Barr virus DNA at diagnosis predicts a poor prognosis in peripheral T-cell lymphomas

2015 ◽  
Vol 15 ◽  
pp. S67 ◽  
Author(s):  
Bradley M. Haverkos ◽  
Ying Huang ◽  
Alejandro Gru ◽  
Robert A. Baiocchi ◽  
Pierluigi Porcu
Keyword(s):  
T Cell ◽  
Poor Prognosis ◽  
Epstein Barr Virus ◽  
Elevated Plasma ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas

Frequent detection of Epstein-Barr virus-infected B cells in peripheral T-cell lymphomas

1998 ◽  
Vol 185 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Joanna W. Y. Ho ◽  
Faith C. S. Ho ◽  
Alexander C. L. Chan ◽  
Raymond H. S. Liang ◽  
Gopesh Srivastava
Keyword(s):  
T Cell ◽  
B Cells ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas

scholarly journals Composite Epstein-Barr Virus-associated T-lymphoblastic and Peripheral T-cell Lymphomas: A Clonal Study

2021 ◽  
Author(s):  
Hiroki Hosoi ◽  
Toshiki Mushino ◽  
Kazutaka Nakashima ◽  
Kodai Kuriyama ◽  
Shinobu Tamura ◽  
...  
Keyword(s):  
T Cell ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas

Association of Epstein-Barr virus with human immunodeficiency virus-negative peripheral T-cell lymphomas in Japan

2006 ◽  
Vol 76 (2) ◽  
pp. 109-118 ◽  
Author(s):  
Yuko Hirose ◽  
Yasufumi Masaki ◽  
Toshioki Sawaki ◽  
Kumiko Shimoyama ◽  
Hiromi Karasawa ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
T Cell ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Immunodeficiency Virus ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas

Pheno- and Genotypic Features of Epstein-Barr Virus Associated B-Cell Lymphoproliferations in Peripheral T-Cell Lymphomas

2009 ◽  
Vol 16 (3) ◽  
pp. 377-383 ◽  
Author(s):  
Gábor Smuk ◽  
Árpád Illés ◽  
Katalin Keresztes ◽  
László Kereskai ◽  
Balázs Márton ◽  
...  
Keyword(s):  
T Cell ◽  
B Cell ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
T Cell Lymphomas ◽  
Epstein Barr ◽  
Peripheral T Cell Lymphomas
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