Osteoid and cartilaginous metaplasia in transplants of rat liver tumours

1958 ◽  
Vol 75 (2) ◽  
pp. 357-362 ◽  
Author(s):  
G. E. Paget ◽  
A. L. Walpole ◽  
Sonia Ashton
Keyword(s):  
Rat Liver ◽  
Liver Tumours

Polyamine levels in chemically induced rat liver tumours

1986 ◽  
Vol 14 (4) ◽  
pp. 695-696 ◽  
Author(s):  
DAVID HAND ◽  
BARRY M. ELLIOTT ◽  
MARTIN GRIFFIN
Keyword(s):  
Rat Liver ◽  
Liver Tumours ◽  
Chemically Induced

scholarly journals Evidence for ethylation of rat liver deoxyribonucleic acid after administration of ethionine

1971 ◽  
Vol 123 (2) ◽  
pp. 175-181 ◽  
Author(s):  
P. F. Swann ◽  
A. E. Pegg ◽  
A. Hawks ◽  
E. Farber ◽  
P. N. Magee
Keyword(s):  
Rat Liver ◽  
Large Dose ◽  
Deoxyribonucleic Acid ◽  
Liver Tumours ◽  
Acidic Hydrolysis ◽  
Considerable Evidence ◽  
Hydrolysis Of

1. Administration of a large dose (500mg/kg body wt.) of 3H-labelled l-ethionine to rats resulted in the incorporation of a small amount of radioactivity into the liver DNA. Considerable evidence that this radioactivity was not due to contamination of the isolated DNA with labelled protein, RNA, S-adenosyl-l-ethionine or l-ethionine was obtained. 2. After acidic hydrolysis of the DNA isolated from the livers of rats treated with labelled l-ethionine, virtually all of the radioactivity present in the DNA was found in a fraction with similar chromatographic properties to 7-ethylguanine. 3. Treatment of rats with comparable doses of l-methionine did not lead to the formation of 7-methylguanine in the liver DNA. 4. These results are discussed in relation to the induction of liver tumours by ethionine.

An evaluation of the mode of action (MoA) and human relevance of rat liver tumours observed in a chronic rat feeding study with silthiofam

2014 ◽  
Vol 229 ◽  
pp. S69
Author(s):  
Joel M. Kronenberg ◽  
Corinne Haines ◽  
Barbara M. Elcombe ◽  
Clifford R. Elcombe
Keyword(s):  
Rat Liver ◽  
Mode Of Action ◽  
Liver Tumours ◽  
Feeding Study

The role of cell death and cell proliferation in the promotion of rat liver tumours by tamoxifen

1996 ◽  
Vol 106 (2) ◽  
pp. 163-169 ◽  
Author(s):  
P. Carthew ◽  
B.M. Nolan ◽  
R.E. Edwards ◽  
L.L. Smith
Keyword(s):  
Cell Proliferation ◽  
Cell Death ◽  
Rat Liver ◽  
Liver Tumours

Histological changes in rat liver tumours treated with high-intensity focused ultrasound

1993 ◽  
Vol 19 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Lili Chen ◽  
Ian Rivens ◽  
Gail Ter Haar ◽  
Sharon Riddler ◽  
C.R. Hill ◽  
...  
Keyword(s):  
Rat Liver ◽  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Liver Tumours ◽  
Histological Changes
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