Polyamine levels in chemically induced rat liver tumours

1986 ◽  
Vol 14 (4) ◽  
pp. 695-696 ◽  
Author(s):  
DAVID HAND ◽  
BARRY M. ELLIOTT ◽  
MARTIN GRIFFIN
1996 ◽  
Vol 17 (9) ◽  
pp. 2077-2080 ◽  
Author(s):  
Yasufumi Omori ◽  
Vladimir Krutovskikh ◽  
Nicolai Mironov ◽  
Hiroyuki Tsuda ◽  
Hiroshi Yamasaki

Life Sciences ◽  
2000 ◽  
Vol 66 (26) ◽  
pp. 2593-2601 ◽  
Author(s):  
Tai-Xing Cui ◽  
Masaru Iwai ◽  
Meiko Hamai ◽  
Yasuhiko Minokoshi ◽  
Takashi Shimazu ◽  
...  

Hepatology ◽  
1996 ◽  
Vol 24 (5) ◽  
pp. 1269-1273 ◽  
Author(s):  
D Trere ◽  
M Derenzini ◽  
V Sirri ◽  
L Montanaro ◽  
W Grigioni ◽  
...  

1971 ◽  
Vol 123 (2) ◽  
pp. 175-181 ◽  
Author(s):  
P. F. Swann ◽  
A. E. Pegg ◽  
A. Hawks ◽  
E. Farber ◽  
P. N. Magee

1. Administration of a large dose (500mg/kg body wt.) of 3H-labelled l-ethionine to rats resulted in the incorporation of a small amount of radioactivity into the liver DNA. Considerable evidence that this radioactivity was not due to contamination of the isolated DNA with labelled protein, RNA, S-adenosyl-l-ethionine or l-ethionine was obtained. 2. After acidic hydrolysis of the DNA isolated from the livers of rats treated with labelled l-ethionine, virtually all of the radioactivity present in the DNA was found in a fraction with similar chromatographic properties to 7-ethylguanine. 3. Treatment of rats with comparable doses of l-methionine did not lead to the formation of 7-methylguanine in the liver DNA. 4. These results are discussed in relation to the induction of liver tumours by ethionine.


Sign in / Sign up

Export Citation Format

Share Document