Drive for thinness in adolescents predicts greater adult BMI in the Growth and Health Study cohort over 20 years

Obesity ◽  
2021 ◽  
Vol 29 (12) ◽  
pp. 2126-2133
Author(s):  
Barbara A. Laraia ◽  
Cindy W. Leung ◽  
A. Janet Tomiyama ◽  
Lorrene D. Ritchie ◽  
Patricia B. Crawford ◽  
...  
Keyword(s):  
Health Study ◽  
Study Cohort ◽  
Drive For Thinness

scholarly journals Prospective Study of Ambient Particulate Matter Exposure and Risk of Pulmonary Embolism in the Nurses’ Health Study Cohort

2015 ◽  
Vol 123 (12) ◽  
pp. 1265-1270 ◽  
Author(s):  
Vivian C. Pun ◽  
Jaime E. Hart ◽  
Christopher Kabrhel ◽  
Carlos A. Camargo ◽  
Andrea A. Baccarelli ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Particulate Matter ◽  
Prospective Study ◽  
Health Study ◽  
Study Cohort ◽  
Ambient Particulate Matter ◽  
Particulate Matter Exposure

scholarly journals Use of Dieselized Farm Equipment and Incident Lung Cancer: Findings from the Agricultural Health Study Cohort

2016 ◽  
Vol 124 (5) ◽  
pp. 611-618 ◽  
Author(s):  
Séverine Tual ◽  
Debra T. Silverman ◽  
Stella Koutros ◽  
Aaron Blair ◽  
Dale P. Sandler ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Health Study ◽  
Study Cohort ◽  
Agricultural Health ◽  
Agricultural Health Study ◽  
Farm Equipment

USE OF AGRICULTURAL PESTICIDES AND LUNG CANCER RISK IN THE AGRICULTURAL HEALTH STUDY COHORT

Epidemiology ◽  
2004 ◽  
Vol 15 (4) ◽  
pp. S178-S179 ◽  
Author(s):  
Michael C.R. Alavanja1 ◽  
Mustafa Dosemeci ◽  
Claudine Samanic ◽  
Jay Lubin ◽  
Charles F. Lynch ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Lung Cancer Risk ◽  
Health Study ◽  
Study Cohort ◽  
Agricultural Health ◽  
Agricultural Pesticides ◽  
Agricultural Health Study

scholarly journals Deciphering the Plasma Proteome of Type 2 Diabetes

2020 ◽  
Author(s):  
Ada Admin ◽  
Mohamed A. Elhadad ◽  
Christian Jonasson ◽  
Cornelia Huth ◽  
Rory Wilson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Growth Hormone Receptor ◽  
Smoking Status ◽  
Underlying Disease ◽  
Sex Hormone Binding Globulin ◽  
Health Study ◽  
Study Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes

With an estimated prevalence of 463 million affected, type 2 diabetes represents a major challenge to health care systems worldwide. Analyzing the plasma proteomes of individuals with type 2 diabetes may illuminate hitherto unknown functional mechanisms underlying disease pathology. We assessed the associations between type 2 diabetes and >1000 plasma proteins in the KORA (Cooperative health research in the Region of Augsburg) F4 cohort (n=993, 110 cases), with subsequent replication in the HUNT3 (Third wave of the Nord-Trøndelag Health Study) cohort (n=940, 149 cases). We computed logistic regression models adjusted for age, sex, BMI, smoking status and hypertension. Additionally, we investigated associations with incident type 2 diabetes and performed two-sample bi-directional Mendelian randomization (MR) analysis to prioritize our results. Association analysis of prevalent type 2 diabetes revealed 24 replicated proteins, of which eight are novel. Proteins showing association with incident type 2 diabetes were aminoacylase-1, growth hormone receptor, and insulin-like growth factor binding protein-2. Aminoacylase-1 was associated with both prevalent and incident type 2 diabetes. MR analysis yielded nominally significant causal effects of type 2 diabetes on cathepsin Z and rennin, both known to have roles in the pathophysiological pathways of cardiovascular disease, and of sex hormone-binding globulin on type 2 diabetes. In conclusion, our high-throughput proteomics study replicated previously reported type 2 diabetes-protein associations, and identified new candidate proteins possibly involved in the pathogenesis of type 2 diabetes.

scholarly journals Deciphering the Plasma Proteome of Type 2 Diabetes

2020 ◽  
Author(s):  
Ada Admin ◽  
Mohamed A. Elhadad ◽  
Christian Jonasson ◽  
Cornelia Huth ◽  
Rory Wilson ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Growth Hormone Receptor ◽  
Smoking Status ◽  
Underlying Disease ◽  
Sex Hormone Binding Globulin ◽  
Health Study ◽  
Study Cohort ◽  
Incident Type ◽  
Incident Type 2 Diabetes

With an estimated prevalence of 463 million affected, type 2 diabetes represents a major challenge to health care systems worldwide. Analyzing the plasma proteomes of individuals with type 2 diabetes may illuminate hitherto unknown functional mechanisms underlying disease pathology. We assessed the associations between type 2 diabetes and >1000 plasma proteins in the KORA (Cooperative health research in the Region of Augsburg) F4 cohort (n=993, 110 cases), with subsequent replication in the HUNT3 (Third wave of the Nord-Trøndelag Health Study) cohort (n=940, 149 cases). We computed logistic regression models adjusted for age, sex, BMI, smoking status and hypertension. Additionally, we investigated associations with incident type 2 diabetes and performed two-sample bi-directional Mendelian randomization (MR) analysis to prioritize our results. Association analysis of prevalent type 2 diabetes revealed 24 replicated proteins, of which eight are novel. Proteins showing association with incident type 2 diabetes were aminoacylase-1, growth hormone receptor, and insulin-like growth factor binding protein-2. Aminoacylase-1 was associated with both prevalent and incident type 2 diabetes. MR analysis yielded nominally significant causal effects of type 2 diabetes on cathepsin Z and rennin, both known to have roles in the pathophysiological pathways of cardiovascular disease, and of sex hormone-binding globulin on type 2 diabetes. In conclusion, our high-throughput proteomics study replicated previously reported type 2 diabetes-protein associations, and identified new candidate proteins possibly involved in the pathogenesis of type 2 diabetes.

scholarly journals Overweight, Obesity, and Mortality in the Nih-aarp Diet and Health Study Cohort

2006 ◽  
Vol 163 (suppl_11) ◽  
pp. S43-S43
Author(s):  
K F Adams ◽  
A Schatzkin ◽  
T B Harris ◽  
V Kipnis ◽  
T Mouw ◽  
...  
Keyword(s):  
Health Study ◽  
Study Cohort

scholarly journals Dietary Fat and Postmenopausal Invasive Breast Cancer in the National Institutes of Health-AARP Diet and Health Study Cohort

2007 ◽  
Vol 99 (6) ◽  
pp. 451-462 ◽  
Author(s):  
A. C. M. Thiebaut ◽  
V. Kipnis ◽  
S.-C. Chang ◽  
A. F. Subar ◽  
F. E. Thompson ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Invasive Breast Cancer ◽  
Dietary Fat ◽  
National Institutes Of Health ◽  
Health Study ◽  
Study Cohort
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