scholarly journals Reproductive factors and postmenopausal hormone use in relation to endometrial cancer risk in the Nurses' Health Study cohort 1976-2004

2009 ◽  
Vol 126 (1) ◽  
pp. 208-216 ◽  
Author(s):  
Stalo Karageorgi ◽  
Susan E. Hankinson ◽  
Peter Kraft ◽  
Immaculata De Vivo
2007 ◽  
Vol 16 (4) ◽  
pp. 723-730 ◽  
Author(s):  
Shih-Chen Chang ◽  
James V. Lacey ◽  
Louise A. Brinton ◽  
Patricia Hartge ◽  
Kenneth Adams ◽  
...  

2006 ◽  
Vol 163 (suppl_11) ◽  
pp. S40-S40
Author(s):  
S C Chang ◽  
J V Lacey Jr ◽  
L Brinton ◽  
P Hartge ◽  
K Adams ◽  
...  

2015 ◽  
Vol 26 (4) ◽  
pp. 627-634 ◽  
Author(s):  
Alison J. Canchola ◽  
James V. Lacey ◽  
Leslie Bernstein ◽  
Pamela L. Horn-Ross

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Zhanwei Wang ◽  
Harvey Risch ◽  
Lingeng Lu ◽  
Melinda L. Irwin ◽  
Susan Mayne ◽  
...  

2008 ◽  
Vol 124 (11) ◽  
pp. 2737-2743 ◽  
Author(s):  
Lindsay M. Morton ◽  
Sophia S. Wang ◽  
Douglas A. Richesson ◽  
Arthur Schatzkin ◽  
Albert R. Hollenbeck ◽  
...  

2007 ◽  
Vol 197 (2) ◽  
pp. e1-e5 ◽  
Author(s):  
Randall R. Odem ◽  
Michelle H. Moniz ◽  
Jenifer E. Allsworth ◽  
Christy R. Bleckman ◽  
Valerie A. Omicioli ◽  
...  

2011 ◽  
Vol 20 (5) ◽  
pp. 971-977 ◽  
Author(s):  
Tao Wang ◽  
Thomas E. Rohan ◽  
Marc J. Gunter ◽  
Xiaonan Xue ◽  
Jean Wactawski-Wende ◽  
...  

2016 ◽  
Vol 183 (3) ◽  
pp. 199-209 ◽  
Author(s):  
Theodore M. Brasky ◽  
Todd R. Sponholtz ◽  
Julie R. Palmer ◽  
Lynn Rosenberg ◽  
Edward A. Ruiz-Narváez ◽  
...  

2009 ◽  
Vol 124 (9) ◽  
pp. 2139-2147 ◽  
Author(s):  
Gretchen L. Gierach ◽  
Shih-Chen Chang ◽  
Louise A. Brinton ◽  
James V. Lacey ◽  
Albert R. Hollenbeck ◽  
...  

Cancers ◽  
2020 ◽  
Vol 12 (9) ◽  
pp. 2407 ◽  
Author(s):  
Thilo Dörk ◽  
Peter Hillemanns ◽  
Clemens Tempfer ◽  
Julius Breu ◽  
Markus C. Fleisch

Endometrial cancer (EC) is the most common cancer affecting the female reproductive organs in higher-income states. Apart from reproductive factors and excess weight, genetic predisposition is increasingly recognized as a major factor in endometrial cancer risk. Endometrial cancer is genetically heterogeneous: while a subgroup of patients belongs to cancer predisposition syndromes (most notably the Lynch Syndrome) with high to intermediate lifetime risks, there are also several common genomic polymorphisms contributing to the spectrum of germline predispositions. Germline variants and somatic events may act in concert to modulate the molecular evolution of the tumor, where mismatch-repair deficiency is common in endometrioid endometrial tumors whereas homologous recombinational repair deficiency has been described for non-endometrioid endometrial tumors. In this review, we will survey the currently known genomic predispositions for endometrial cancer and discuss their relevance for clinical management in terms of counseling, screening and novel treatments.


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