Salmon peptides limit obesity‐associated metabolic disorders by modulating a gut‐liver axis in vitamin D‐deficient mice

Obesity ◽  
2021 ◽  
Vol 29 (10) ◽  
pp. 1635-1649
Author(s):  
Marion Valle ◽  
Patricia L. Mitchell ◽  
Geneviève Pilon ◽  
Thibault Varin ◽  
Loïc Hénault ◽  
...  
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders ◽  
Deficient Mice

scholarly journals Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice

2019 ◽  
Vol 482 ◽  
pp. 1-10 ◽  
Author(s):  
Wenqiong Xu ◽  
Hongyi Zhou ◽  
Hongzhuan Xuan ◽  
Pradip Saha ◽  
Gongxian Wang ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Metabolic Disorders ◽  
Deficient Mice

Vitamin D, Metabolic Disorders and Reproduction

2014 ◽  
pp. 51-57
Author(s):  
Diana Jędrzejuk ◽  
Andrzej Milewicz ◽  
Felicja Lwow ◽  
Anna Brona
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders

scholarly journals The Role of Vitamin D and Vitamin D Receptor in Immunity toLeishmania majorInfection

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
James P. Whitcomb ◽  
Mary DeAgostino ◽  
Mark Ballentine ◽  
Jun Fu ◽  
Martin Tenniswood ◽  
...  
Keyword(s):  
Vitamin D ◽  
Immune Responses ◽  
Vitamin D Receptor ◽  
Leishmania Major ◽  
Active Form ◽  
Wild Type ◽  
Vitamin D Signaling ◽  
Deficient Mice ◽  
Th 1

Vitamin D signaling modulates a variety of immune responses. Here, we assessed the role of vitamin D in immunity to experimental leishmaniasis infection in vitamin D receptor-deficient mice (VDRKO). We observed that VDRKO mice on a genetically resistant background have decreasedLeishmania major-induced lesion development compared to wild-type (WT) mice; additionally, parasite loads in infected dermis were significantly lower at the height of infection. Enzymatic depletion of the active form of vitamin D mimics the ablation of VDR resulting in an increased resistance toL. major. Conversely, VDRKO or vitamin D-deficient mice on the susceptible Th2-biased background had no change in susceptibility. These studies indicate vitamin D deficiency, either through the ablation of VDR or elimination of its ligand, 1,25D3, leads to an increase resistance toL. majorinfection but only in a host that is predisposed for Th-1 immune responses.

scholarly journals Insulin resistance in vitamin D-deficient mice is alleviated by n-acetylcysteine

Oncotarget ◽  
2017 ◽  
Vol 8 (38) ◽  
pp. 63281-63289 ◽  
Author(s):  
Zhao-Hui Cui ◽  
Qi Yuan ◽  
Li Mao ◽  
Feng-Li Chen ◽  
Feng Ji ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin D ◽  
Deficient Mice

scholarly journals Evaluation of Vitamin D Fractions in Obese Hypertensive Patients

2020 ◽  
Vol 17 (5) ◽  
pp. 1660
Author(s):  
Marta Pelczyńska ◽  
Teresa Grzelak ◽  
Marcelina Sperling ◽  
Matylda Kręgielska-Narożna ◽  
Paweł Bogdański ◽  
...  
Keyword(s):  
Vitamin D ◽  
Metabolic Disorders ◽  
Hdl Cholesterol ◽  
Predictive Marker ◽  
Lipid Profiles ◽  
Anthropometric Parameters ◽  
Hypertensive Patients ◽  
Hydroxyvitamin D ◽  
Glucose Levels ◽  
Free Vitamin D

Vitamin D fractions can be involved in the pathogenesis of metabolic disorders, but their concentrations are rarely determined. The aim of this study was to evaluate the concentration of vitamin D fractions in obese hypertensive patients and to determine its associations with anthropometric parameters, glucose levels, and lipid profiles. A total of 85 obese hypertensive patients (OBHT) and 40 nonobese nonhypertensive subjects (NOBNHT) underwent biochemical measurements of lipid profiles, glycemia, 25-hydroxyvitamin D (25(OH)D), free vitamin D (free25(OH)D), vitamin D binding protein, albumin levels. Moreover, free25(OH)D and bioavailable25(OH)D (bio25(OH)D) concentrations were calculated. Blood pressure and anthropometric measurements were performed. Differences between groups (p < 0.001) were found for 25(OH)D (OBHT 40.25 ± 18.02 vs. NOBNHT 64.10 ± 22.29 nmol/L), free25(OH)D (9.77 (7.46; 11.49) vs. 13.80 (10.34; 16.82) pmol/L), bioavailable 25(OH)D (3.7 (2.8; 4.4) vs. 5.4 (4.2; 6.7) nmol/L), and calculated free25(OH)D (7.82 (5.54; 11.64) vs. 10.46(8.06;16.28) pmol/L, p = 0.002). The OBHT patients showed no relationship between vitamin D fractions concentration and glucose or lipids level, although it was associated with anthropometric parameters. In the NOBNHT group, vitamin D fractions correlated positively with HDL cholesterol and negatively with triglyceridemia and hip circumference. Vitamin D fractions were decreased in obese hypertensive subjects, and were associated with anthropometric parameters, but not with glucose level or lipid profiles; they thus cannot be considered as a predictive marker of metabolic disorders in this group of patients.

scholarly journals Mineral nutrition of modern poultry genotypes

2009 ◽  
Vol 25 (5-6-1) ◽  
pp. 399-409 ◽  
Author(s):  
M. Lukic ◽  
Z. Pavlovski ◽  
Z. Skrbic
Keyword(s):  
Vitamin D ◽  
Particle Size ◽  
Mineral Nutrition ◽  
Metabolic Disorders ◽  
Practical Application ◽  
Genetic Progress ◽  
Adequate Nutrition ◽  
Factors Influencing ◽  
Micro Elements

In the latest research relating to mineral nutrition of poultry, the interest in several nutrients is prevailing for which in ordinary diets additional sources are necessary. In mineral nutrition of layers constantly the calcium (Ca) requirements are reviewed as one of the most important factors influencing the quality of eggs and bones, in regard to adequate level, source and particle size of added Ca, as well as mutual balance with other nutrients, primarily vitamin D, phosphorus (P) and certain micro-elements. Also, efforts are directed towards possibility and justification for use of new source of vitamin D, existing recommendations related to P are reviewed as well as increase of possibility for adoption of phytine bound phosphorus in diets using enzyme phytase, as well as investigation of organic forms of certain micro-element sources. Certain researches which combine the latest studies of the mineral nutrition of poultry are especially interesting also for practical application. Contrary to layers, focus of research of mineral nutrition of broilers is on phosphorus and application of enzyme phytase. In general, researches of the mineral nutrition of modern poultry genotypes are always actual, considering that their objective is to support genetic progress with adequate nutrition, but also to solve increasing problems relating to product quality, metabolic disorders and ecology.

Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice

2007 ◽  
Vol 26 (2) ◽  
pp. 75-84 ◽  
Author(s):  
Martina Hesse ◽  
Leopold F. Fröhlich ◽  
Ute Zeitz ◽  
Beate Lanske ◽  
Reinhold G. Erben
Keyword(s):  
Vitamin D ◽  
Bone Mineral ◽  
Glucose Homeostasis ◽  
Vitamin D Signaling ◽  
Fgf 23 ◽  
Deficient Mice
Sign in / Sign up

Export Citation Format

Share Document