scholarly journals Randomized Controlled Trial of Behavioral Weight Loss and Stepped Care for Binge‐Eating Disorder: 12‐Month Follow‐up

Obesity ◽  
2020 ◽  
Vol 28 (11) ◽  
pp. 2116-2124 ◽  
Author(s):  
Carlos M. Grilo ◽  
Marney A. White ◽  
Valentina Ivezaj ◽  
Ralitza Gueorguieva
Keyword(s):  
Weight Loss ◽  
Randomized Controlled Trial ◽  
Eating Disorder ◽  
Binge Eating ◽  
Binge Eating Disorder ◽  
Controlled Trial ◽  
Stepped Care ◽  
Behavioral Weight Loss ◽  
Randomized Controlled

Randomized controlled trial testing behavioral weight loss versus multi-modal stepped-care treatment for binge eating disorder

2016 ◽  
Vol 33 (S1) ◽  
pp. S163-S163 ◽  
Author(s):  
C. Grilo
Keyword(s):  
Weight Loss ◽  
Eating Disorder ◽  
Binge Eating ◽  
Binge Eating Disorder ◽  
Mixed Models ◽  
Controlled Trial ◽  
Stepped Care ◽  
Behavioral Weight Loss ◽  
Co Morbidity ◽  
Remission Rates

IntroductionBinge eating disorder (BED) is prevalent, associated with obesity and elevated psychiatric co-morbidity, and represents a treatment challenge.Objective and aimsA controlled comparison of multi-modal, stepped-care versus behavioral-weight-loss (BWL) for BED.MethodsOne hundred and ninety-one patients (71% female, 79% white) with BED and co-morbid obesity (mean BMI 39) were randomly assigned to 6 months of BWL (n = 39) or stepped-care (n = 152). Within stepped-care, patients started BWL for one month; treatment-responders continued BWL while non-responders switched to cognitive-behavioral-therapy (CBT) and all stepped-care patients were additionally randomized to anti-obesity medication or placebo (double-blind) for five months. Independent assessments were performed by research-clinicians at baseline, throughout treatment, and post-treatment (90% assessed) with reliably-administered structured interviews.ResultsIntent-to-treat analyses of remission rates (0 binges/month) revealed BWL and stepped-care did not differ significantly overall (74% vs 64%); within stepped-care, remission rates differed (range 40% - 79%) with medication significantly superior to placebo (P < 0.005) and among initial non-responders switched to CBT (P < 0.002). Mixed-models analyses of binge eating frequency revealed significant time effects but BWL and stepped-care did not differ overall; within stepped-care, medication was significantly superior to placebo overall and among initial non-responders switched to CBT. Mixed models revealed significant weight-loss but BWL and stepped-care did not differ overall; within stepped-care, medication was significantly superior to placebo overall and among both initial responders continued on BWL and non-responders switched to CBT.ConclusionsOverall, BWL and stepped-care treatments produced improvements in binge-eating and weight loss in obese BED patients. Anti-obesity medication enhanced outcomes within a stepped-care model.Disclosure of interestThe author has not supplied his/her declaration of competing interest.

Adapted motivational interviewing for women with binge eating disorder: A randomized controlled trial.

2008 ◽  
Vol 22 (3) ◽  
pp. 417-425 ◽  
Author(s):  
Stephanie E. Cassin ◽  
Kristin M. von Ranson ◽  
Kenneth Heng ◽  
Joti Brar ◽  
Amy E. Wojtowicz
Keyword(s):  
Randomized Controlled Trial ◽  
Eating Disorder ◽  
Binge Eating ◽  
Motivational Interviewing ◽  
Binge Eating Disorder ◽  
Controlled Trial ◽  
Randomized Controlled
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