scholarly journals Dietary fat restriction increases fat taste sensitivity in people with obesity

Obesity ◽  
2016 ◽  
Vol 24 (2) ◽  
pp. 328-334 ◽  
Author(s):  
Lisa P. Newman ◽  
Dieuwerke P. Bolhuis ◽  
Susan J. Torres ◽  
Russell S.J. Keast
Keyword(s):  
Dietary Fat ◽  
Taste Sensitivity ◽  
Fat Taste

scholarly journals Bitter Taste Sensitivity Is Determined by TAS2R38 Haplotype, Associated with Saturated Fat Intake and Is Lower in Overweight and Obese Compared to Normal Weight UK adults

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1271-1271
Author(s):  
Leta Pilic ◽  
Catherine Anna-Marie Graham ◽  
Nisrin Hares ◽  
Megan Brown ◽  
Jonathan Kean ◽  
...  
Keyword(s):  
Dietary Fat ◽  
Bitter Taste ◽  
Saturated Fat ◽  
Normal Weight ◽  
Taste Perception ◽  
Taste Sensitivity ◽  
Lower Sensitivity ◽  
Fat Intake ◽  
Fat Taste ◽  
Total Fat

Abstract Objectives Taste perception (sensitivity) may be determined by genetic variations in taste receptors and it affects food intake. Lower fat taste sensitivity is associated with higher dietary fat intake and body mass index (BMI). Recently, associations between bitter and fat taste sensitivity have been reported whereby bitter taste perception may be involved in textural perception of dietary fat. However, it is not clear if lower sensitivity to bitter taste would lead to an actual higher fat intake. Our objectives were to explore the associations between haplotypes in the bitter taste receptor TAS2R38, bitter taste sensitivity and fat intake and if bitter taste sensitivity is lower in individuals with higher BMI. Methods Ethical approval was obtained from the St Mary's and Oxford Brookes University Ethics Committee. Eighty-eight healthy Caucasian participants (44% male and 56% female; mean BMI 24.9 ± 4.8 kg/m2 and mean age 35 ± 14 years) completed this cross-sectional study. Height and weight were measured and genotyping performed for rs713598, rs1726866, rs10246939 genetic variants in the TAS2R38. Haplotypes were determined with Haploview software. Participants rated the intensity of a phenylthiocarbamide (PTC) impregnated strip on the general Labelled Magnitude Scale (gLMS) to determine bitter taste sensitivity and were classified as bitter tasters and non-tasters. Dietary fat intake was calculated from the EPIC-Norfolk Food Frequency Questionnaire and expressed as % total energy intake. Results TAS2R38 haplotypes were associated with bitter taster status (P < 0.005). PTC ratings of intensity were negatively correlated with % saturated fat (SFA) intake (rs = −0.256, P = 0.016). %SFA and %total fat (rs = 0.656, P < 0.005) and %total fat and energy intake (kcal) (rs = 0.225, P = 0.035) were positively correlated. Normal weight participants rated PTC strips as more intense compared to overweight and obese participants (mean rank 53 vs. 41, P = 0.033). Conclusions Bitter taste perception is determined by genetics and lower sensitivity to this taste is associated with higher intake of SFA. Lower bitter taste sensitivity in overweight/obese participants suggests that impaired bitter taste may be associated with an overall unhealthier and more energy dense dietary pattern. Funding Sources St Mary's and Oxford Brookes University.

scholarly journals Effect of dietary fat intake and genetics on fat taste sensitivity: a co-twin randomized controlled trial

2018 ◽  
Vol 107 (5) ◽  
pp. 683-694 ◽  
Author(s):  
Andrew Costanzo ◽  
Caryl Nowson ◽  
Liliana Orellana ◽  
Dieuwerke Bolhuis ◽  
Konsta Duesing ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Dietary Fat ◽  
Controlled Trial ◽  
Taste Sensitivity ◽  
Fat Intake ◽  
Randomized Controlled ◽  
Dietary Fat Intake ◽  
Fat Taste

scholarly journals Genetic differences in fat taste sensitivity and dietary intake in a UK female cohort

2021 ◽  
Vol 92 ◽  
pp. 104202
Author(s):  
Catherine A.M. Graham ◽  
Leta Pilic ◽  
Alexandra King ◽  
Jonathan E. Nixon ◽  
Julie Pipe ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Genetic Differences ◽  
Taste Sensitivity ◽  
Fat Taste ◽  
Female Cohort

scholarly journals The Association between Fat Taste Sensitivity, Eating Habits, and Metabolic Health in Menopausal Women

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4506
Author(s):  
Aleksandra Skoczek-Rubińska ◽  
Agata Chmurzynska ◽  
Agata Muzsik-Kazimierska ◽  
Joanna Bajerska
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Fatty Acid ◽  
Eating Habits ◽  
Taste Sensitivity ◽  
Acid Sensitivity ◽  
Menopausal Women ◽  
Postmenopausal Status ◽  
Fat Taste ◽  
Eating Occasions

The aim of our study was to evaluate the associations between sensitivity to fat taste, eating habits and BMI value in a sample of menopausal Polish women. In a population of 95 women, fat taste thresholds with oleic acid were determined, allowing us to classify each woman as a hypersensitive or hyposensitive taster. Eating habits were assessed using a validated KomPAN questionnaire for food frequency. Dietary intake was evaluated based on a food diary. Selected biochemical parameters were measured using a Konelab20i biochemical analyzer. Anthropometric parameters and blood pressure were also measured. Twenty-two menopausal women were classified as hyposensitive to fat taste and 73 as hypersensitive. The hyposensitive tasters were significantly older (p = 0.006), with the majority of them (92%) being postmenopausal (p < 0.001); this group had significantly higher BMI values (p < 0.001) and other adiposity indicators compared to their hypersensitive counterparts. The hyposensitive tasters had higher blood pressure (systolic blood pressure; SBP p = 0.030; diastolic blood pressure; DBP p = 0.003), glucose (p = 0.011) and triacylglycerols levels than the hypersensitive tasters (p = 0.031). Almost half of them had diagnosed metabolic syndrome. Daily eating occasions were associated with low oral fatty acid sensitivity, irrespective of age (p = 0.041) and BMI value (p = 0.028). There were also significant associations between frequency of consumption of meats and eggs, as well as snacks and fast foods and low oral fatty acid sensitivity before adjustment for potential confounders (both associations p < 0.05), which remained after adjustment for age (both associations p < 0.05), but not after adjustment for BMI. A multivariate logistic regression analysis showed that higher BMI value (p = 0.003), along with postmenopausal status (p = 0.003), were associated with low fat taste sensitivity irrespective of age and consumed percentage energy from fat. Postmenopausal status and BMI are associated with low fat taste sensitivity. Fat hyposensitivity may also play a role in eating habits, leading to increased eating occasions and favoring certain types of food. These eating habits may determine increased body weight and the occurrence of metabolic syndrome in mid-life women, especially those who have undergone menopause and have been exposed to the physiological changes which are conducive to these relationships.

scholarly journals Fat Taste Sensitivity Is Associated with Short-Term and Habitual Fat Intake

Nutrients ◽  
2017 ◽  
Vol 9 (7) ◽  
pp. 781 ◽  
Author(s):  
Andrew Costanzo ◽  
Liliana Orellana ◽  
Caryl Nowson ◽  
Konsta Duesing ◽  
Russell Keast
Keyword(s):  
Taste Sensitivity ◽  
Fat Intake ◽  
Short Term ◽  
Fat Taste

scholarly journals A Fatty Acid Mouth Rinse Decreases Self-Reported Hunger and Increases Self-Reported Fullness in Healthy Australian Adults: A Randomized Cross-Over Trial

Nutrients ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 678
Author(s):  
Andrew Costanzo ◽  
Catherine G. Russell ◽  
Simone Lewin ◽  
Russell Keast
Keyword(s):  
Body Mass Index ◽  
Oleic Acid ◽  
Fatty Acid ◽  
Oral Cavity ◽  
Analogue Scale ◽  
Area Under The Curve ◽  
Taste Sensitivity ◽  
Mouth Rinse ◽  
Satiety Response ◽  
Fat Taste

Fatty acid (FA) chemoreception in the oral cavity, known as fat taste, may trigger a satiety response that is homologous to FA chemoreception in the gastrointestinal tract. In addition, individuals with an impaired fat taste sensitivity are more likely to have an impaired satiety response. This study aimed to assess the effect of an FA mouth rinse on self-reported appetite, and to determine if the effect is modified by fat taste sensitivity. Thirty-one participants (age, 32.0 ± 8.4 y; body mass index (BMI), 26.1 ± 8.1 kg/m2) were studied on four separate days to evaluate the effect of a 20 mM oleic acid (OA) mouth rinse (in duplicate) compared to a control (in duplicate) on self-reported appetite by using a visual analogue scale (VAS) every 30 min for three hours following a standardized low-fat breakfast. The area under the curve ratings for fullness were greater (p = 0.003), and those for hunger were lower (p = 0.002) following the OA rinse compared to the control. The effect of the OA rinse was greater in individuals who were hypersensitive to fat taste compared to moderately sensitive and hyposensitive individuals for fullness (p < 0.010) and hunger (p < 0.010) ratings. In summary, an OA mouth rinse decreases self-reported hunger and increases self-reported fullness, particularly in those who are more sensitive to fat taste. FA receptors in the oral cavity may be potential targets to regulate appetite.

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