scholarly journals Energy intake, nonexercise physical activity, and weight loss in responders and nonresponders: The Midwest Exercise Trial 2

Obesity ◽  
2015 ◽  
Vol 23 (8) ◽  
pp. 1539-1549 ◽  
Author(s):  
Stephen D. Herrmann ◽  
Erik A. Willis ◽  
Jeffery J. Honas ◽  
Jaehoon Lee ◽  
Richard A. Washburn ◽  
...  
Appetite ◽  
2021 ◽  
pp. 105273
Author(s):  
Sasha Fenton ◽  
Tracy L. Burrows ◽  
Clare E. Collins ◽  
Elizabeth G. Holliday ◽  
Gregory S. Kolt ◽  
...  

2009 ◽  
Vol 69 (1) ◽  
pp. 34-38 ◽  
Author(s):  
C. R. Hankey

Treatments to induce weight loss for the obese patient centre on the achievement of negative energy balance. This objective can theoretically be attained by interventions designed to achieve a reduction in energy intake and/or an increase in energy expenditure. Such ‘lifestyle interventions’ usually comprise one or more of the following strategies: dietary modification; behaviour change; increases in physical activity. These interventions are advocated as first treatment steps in algorithms recommended by current clinical obesity guidelines. Medication and surgical treatments are potentially available to those unable to implement ‘lifestyle interventions’ effectively by achieving losses of between 5 kg and 10 kg. It is accepted that the minimum of 5% weight loss is required to achieve clinically-meaningful benefits. Dietary treatments differ widely. Successful weight loss is most often associated with quantification of energy intake rather than macronutrient composition. Most dietary intervention studies secure a weight loss of between 5 kg and 10 kg after intervention for 6 months, with gradual weight regain at 1 year where weight changes are 3–4 kg below the starting weight. Some dietary interventions when evaluated at 2 and 4 years post intervention report the effects of weight maintenance rather than weight loss. Specific anti-obesity medications are effective adjuncts to weight loss, in most cases doubling the weight loss of those given dietary advice only. Greater physical activity alone increases energy expenditure by insufficient amounts to facilitate clinically-important weight losses, but is useful for weight maintenance. Weight losses of between half and three-quarters of excess body weight are seen at 10 years post intervention with bariatric surgery, making this arguably the most effective weight-loss treatment.


Obesity ◽  
2020 ◽  
Vol 28 (5) ◽  
pp. 882-892 ◽  
Author(s):  
Christoph Höchsmann ◽  
James L. Dorling ◽  
John W. Apolzan ◽  
Neil M. Johannsen ◽  
Daniel S. Hsia ◽  
...  

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S96-S97
Author(s):  
Bruce W. Bailey ◽  
Dennis J. Jacobsen ◽  
James D. LeCheminant ◽  
Erik P. Kirk ◽  
Joseph E. Donnelly

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S96???S97
Author(s):  
Bruce W. Bailey ◽  
Dennis J. Jacobsen ◽  
James D. LeCheminant ◽  
Erik P. Kirk ◽  
Joseph E. Donnelly

Obesity ◽  
2013 ◽  
Vol 22 (2) ◽  
pp. 363-370 ◽  
Author(s):  
James P. DeLany ◽  
David E. Kelley ◽  
Kazanna C. Hames ◽  
John M. Jakicic ◽  
Bret H. Goodpaster

2007 ◽  
Vol 166 (12) ◽  
pp. 1374-1380 ◽  
Author(s):  
M. Franco ◽  
P. Ordunez ◽  
B. Caballero ◽  
J. A. Tapia Granados ◽  
M. Lazo ◽  
...  

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A13-A13
Author(s):  
H Yang ◽  
M Garaulet ◽  
P Li ◽  
C Bandin ◽  
C Lin ◽  
...  

Abstract Introduction Obesity is a major health problem. Many treatments have been designed to help overweight/obese people to lose weight, but their effectiveness is highly variable. The same treatments may work for some persons while others have no responses — weight loss resistance. We tested whether the daily rhythm of cardiac autonomic control contributes to weight loss resistance. Methods We studied 39 overweight/obese Caucasian women (BMI>25; age: 21–62 years old) who completed (1) an obesity dietary treatment of up to 30 weeks with weekly assessments of body weight, and (2) ambulatory monitoring of electrocardiogram (ECG) for up to 3.5 days. Heartbeat intervals were derived from ECG. Cardiac autonomic control was assessed in each 1-h bin by examining the temporal correlation in heartbeat fluctuations — a nonlinear measure that quantifies the delicate dynamic interplay between sympathetic and vagal outflows. Daily rhythm was estimated using the cosinor analysis. Results Weight loss was highly variable (range: 0.68%-21.78 % of initial body weight). The correlation in heartbeat fluctuations displayed a 24-h rhythm (p<0.0001) with fewer correlations (more random) during the nighttime. The phase (peak timing) of the rhythm was highly variable, i.e., 10AM to 8PM for most participants, and after midnight in four participants. Weight loss evolution depended on the phase (p=0.006) in a nonlinear manner. Specifically, participants with the phase between 2PM-8PM lost weight faster than those with phases before 2PM and those after 8PM. The effect was independent of total energy intake, physical activity level, and sleep/wake schedules. Conclusion Cardiac autonomic control in overweight/obese women displayed a daily rhythm. The timing of the rhythm had previously un-identified contributions to weight loss. The inter-individual differences in the timing may reflect different circadian regulation of autonomic function and its interaction with the daily behavioral cycle. Support This work was supported by NIH grants R01AG048108, RF1AG059867, RF1AG064312, R01AG017917, and R01NS078009.


2020 ◽  
Vol 105 (4) ◽  
pp. e1601-e1611 ◽  
Author(s):  
Jasper Most ◽  
Abby D Altazan ◽  
Marshall St. Amant ◽  
Robbie A Beyl ◽  
Eric Ravussin ◽  
...  

Abstract Context This study was designed to understand causes and critical periods for postpartum weight retention by characterizing changes in body composition, energy intake, energy expenditure and physical activity in women with obesity during pregnancy and postpartum. Design In this prospective, observational cohort study, body composition (plethysmography), energy expenditure (doubly labeled water, whole-body room calorimetry), physical activity (accelerometry), metabolic biomarkers, and eating behaviors were measured. Energy intake was calculated by the intake-balance method for pregnancy, and for 2 postpartum periods (0 to 6 months and 6 to 12 months). Results During the 18-month observation period, weight loss occurred in 16 (43%) women (mean ± SEM, −4.9 ± 1.6 kg) and weight retention occurred in 21 (57%) women (+8.6 ± 1.4 kg). Comparing women with postpartum weight loss and weight retention, changes in body weight were not different during pregnancy (6.9 ± 1.0 vs 9.5 ± 0.9 kg, P = 0.06). After pregnancy, women with postpartum weight loss lost −3.6 ± 1.8 kg fat mass whereas women with weight retention gained 6.2 ± 1.7 kg fat mass (P < 0.001). Women with postpartum weight loss reduced energy intake during the postpartum period (compared with during pregnancy) by 300 kcal/d (1255 kJ/d), while women with weight retention increased energy intake by 250 kcal/d (1046 kJ/d, P < 0.005). There were no differences in the duration of breastfeeding, eating behavior, or metabolic biomarkers. Conclusions Postpartum weight gain was the result of increased energy intake after pregnancy rather than decreased energy expenditure. Dietary intake recommendations are needed for women with obesity during the postpartum period, and women should be educated on the risk of overeating after pregnancy.


Circulation ◽  
2013 ◽  
Vol 127 (suppl_12) ◽  
Author(s):  
Erica J Ambeba ◽  
Mindi A Styn ◽  
Maria M Brooks ◽  
Rhobert W Evans ◽  
Lora E Burke

Introduction: Obesity is linked to the development of insulin resistance (IR) and type 2 diabetes. Weight loss achieved by lifestyle modification could improve insulin sensitivity (IS). However, weight loss is difficult to maintain, and individuals often weight cycle, potentially placing them at greater risk for adverse health outcomes. Objective: The purpose of this secondary analysis was to examine how long-term changes in weight are associated with changes in factors related to the development of diabetes (IR and IS) among obese adults enrolled in a 24-month behavioral weight loss trial. Methods: The sample (N=66) included non-diabetic adults who lost and regained at least 10 lbs during the 24-month trial. All participants received standard behavioral weight loss treatment during the first 18 months. Assessments were conducted at baseline, 6, 12, 18, and 24 months. IR was assessed using the homeostatic model assessment (HOMA), and IS was assessed using the quantitative insulin sensitivity check for insulin sensitivity (QUICKI). Linear mixed modeling was used to examine the association between % changes in weight and % changes in fasting insulin, HOMA, and QUICKI. All models were adjusted for time, age, gender, race, % change in energy intake, and % change in physical activity. Results: The sample was 80% female and 86% White. At baseline, the mean (±SD) values were: age, 48.4±7.4 years; BMI, 34.5±4.4 kg/m 2 ; energy intake, 2176.8±603.8 kcal/day; physical activity, 11.4±13.6 MET- hr/week; plasma insulin, 16.9±6.0 μU/mL; HOMA, 4.1±1.7; and QUICKI, 0.3±.02. On average, compared to baseline, participants experienced an 11% decrease in weight (p<.0001), a 9% decrease in insulin (p=.004), a 10% decrease in HOMA (p=.01), and a 2% increase in QUICKI (p=.0003) at 6 months. Following 6-month weight loss, an average of 8.4% weight was regained by 24 months (p<.0001), and the positive changes observed in the other measures were partially reversed, e.g., a 19% increase in insulin (p=.001), a 26% increase in HOMA (p=.001), and a 2% decrease in QUICKI (p=.0002). Overall, weight change was positively associated with changes in insulin [b(se)=0.5(0.1), p≤.0001] and HOMA [b(se)=0.8(0.2), p≤.0001], and negatively associated with a change in QUICKI [b(se)= -0.2(0.1), p≤.0001]. Conclusion: In this unique sample of participants who weight cycled during a 24-month trial, weight loss improved metabolic outcomes; however, this was partially attenuated when weight was regained. These results reveal the effects of changes in weight on metabolic outcomes and highlight the importance of sustaining healthy lifestyle changes that support weight loss maintenance and improved metabolic outcomes.


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