Effect of two different cytoprotectives, ethiofos and β-NGF, on cisplatin-induced toxicity in Schwann cell cultures; a preliminary study

2004 ◽  
Vol 35 (2) ◽  
pp. 96-104
Author(s):  
K. Jirsová ◽  
V. Mandys ◽  
P.R. Bär
Keyword(s):  
Schwann Cell ◽  
Cell Cultures ◽  
Preliminary Study

scholarly journals Cerebellar granule cells contain a membrane mitogen for cultured Schwann cells.

1989 ◽  
Vol 108 (2) ◽  
pp. 607-611 ◽  
Author(s):  
P W Mason ◽  
J W Bigbee ◽  
G H DeVries
Keyword(s):  
Cell Proliferation ◽  
Schwann Cell ◽  
Schwann Cells ◽  
Cell Cultures ◽  
Granule Cell ◽  
Granule Cells ◽  
Cerebellar Granule Cells ◽  
Proteoglycan Synthesis ◽  
Cerebellar Granule ◽  
Mitogenic Signal

Proliferation of Schwann cells is one of the first events that occurs after contact with a growing axon. To further define the distribution and properties of this axonal mitogen, we have (a) cocultured cerebellar granule cells, which lack glial ensheathment in vivo with Schwann cells; and (b) exposed Schwann cell cultures to isolated granule cell membranes. Schwann cells cocultured with granule cells had a 30-fold increase in the labeling index over Schwann cells cultured alone, suggesting that the mitogen is located on the granule cell surface. Inhibition of granule cell proteoglycan synthesis caused a decrease in the granule cells' ability to stimulate Schwann cell proliferation. Membranes isolated from cerebellar granule cells when added to Schwann cell cultures caused a 45-fold stimulation in [3H]thymidine incorporation. The granule cell mitogenic signal was heat and trypsin sensitive and did not require lysosomal processing by Schwann cells to elicit its proliferative effect. The ability of granule cells and their isolated membranes to stimulate Schwann cell proliferation suggests that the mitogenic signal for Schwann cells is a ubiquitous factor present on all axons regardless of their ultimate state of glial ensheathment.

Enrichment of Schwann cell cultures from neonatal rat sciatic nerve by differential adhesion

1981 ◽  
Vol 207 (2) ◽  
pp. 433-444 ◽  
Author(s):  
B.Q. Kreider ◽  
A. Messing ◽  
H. Doan ◽  
S.U. Kim ◽  
R.P. Lisak ◽  
...  
Keyword(s):  
Sciatic Nerve ◽  
Schwann Cell ◽  
Cell Cultures ◽  
Neonatal Rat ◽  
Rat Sciatic Nerve ◽  
Differential Adhesion

α-Sialyl cholesterol increases laminin in Schwann cell cultures and attenuates cytostatic drug-induced reduction of laminin

1994 ◽  
Vol 654 (1) ◽  
pp. 118-128 ◽  
Author(s):  
Pierre N.M. Konings ◽  
Ria L.A. Philipsen ◽  
Gerrit H. Veeneman ◽  
GéS.F. Ruigt
Keyword(s):  
Schwann Cell ◽  
Cell Cultures ◽  
Cytostatic Drug ◽  
Drug Induced

Efficacy of Various Durations of In Vitro Predegeneration on the Cell Count and Purity of Rat Schwann-Cell Cultures

2010 ◽  
Vol 27 (1) ◽  
pp. 197-203 ◽  
Author(s):  
Armin Kraus ◽  
Joachim Täger ◽  
Konrad Kohler ◽  
Theodora Manoli ◽  
Max Haerle ◽  
...  
Keyword(s):  
Schwann Cell ◽  
Cell Count ◽  
Cell Cultures

scholarly journals Diabetic Status of People Affected by Leprosy in Donorojo Leprosy Recovered Village: A Cross Sectional Study

2021 ◽  
pp. 191-199
Author(s):  
Nadhila Beladina ◽  
Asri Adisasmita
Keyword(s):  
Diabetes Mellitus ◽  
Schwann Cell ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Central Java ◽  
Diabetic Status ◽  
Leprosy Patients ◽  
Preliminary Study ◽  
Prevalence Of Diabetes Mellitus

Background: Just like diabetes, leprosy also cause painless neuropathic ulcers which process is mediated by Schwann-cell. Biochemical changes on leprosy patients presumed to have role on pathogenesis of diabetes mellitus.  Methods: This study is cross-sectional study aimed to know further about diabetic status on population of people affected by leprosy, as the preliminary study to prove the association between diabetes mellitus and leprosy.  Data, such as diabetic status, type of leprosy, grade of disability, and other variables are collected from 127 people affected by leprosy in Donorojo leprosy recovered village.Result: Result showed that 19.7% are having diabetes mellitus, and other 23.6% are in pre-diabetic condition. This number is higher than prevalence of diabetes mellitus in Central Java (2.09%) and Indonesia (2%).Conclusion : Further research is needed to prove the association between leprosy and diabetic status.  All leprosy patients should be recommended to be routinely screened for diabetes mellitus.

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