In-vivo high resolution three-dimensional MRI studies of rat joints at 7 T

2003 ◽  
Vol 16 (8) ◽  
pp. 484-493 ◽  
Author(s):  
P. Faure ◽  
B.-T. Doan ◽  
J.-C. Beloeil
Keyword(s):  
High Resolution ◽  
Three Dimensional ◽  
Mri Studies

High-Resolution Ultrasound Imaging of Human Skin In Vivo by Using Three-Dimensional Ultrasound Microscopy

2012 ◽  
Vol 38 (10) ◽  
pp. 1833-1838 ◽  
Author(s):  
Kazutoshi Kumagai ◽  
Hideyuki Koike ◽  
Ryo Nagaoka ◽  
Shingo Sakai ◽  
Kazuto Kobayashi ◽  
...  
Keyword(s):  
High Resolution ◽  
Human Skin ◽  
Ultrasound Imaging ◽  
Three Dimensional ◽  
Ultrasound Microscopy

scholarly journals In vivo, high-resolution, three-dimensional imaging of port wine stain microvasculature in human skin

2013 ◽  
Vol 45 (10) ◽  
pp. 628-632 ◽  
Author(s):  
Gangjun Liu ◽  
Wangcun Jia ◽  
J. Stuart Nelson ◽  
Zhongping Chen
Keyword(s):  
High Resolution ◽  
Human Skin ◽  
Three Dimensional ◽  
Port Wine Stain ◽  
Port Wine ◽  
Three Dimensional Imaging

scholarly journals High-resolution three-dimensional in vivo imaging of atherosclerotic plaque

1999 ◽  
Vol 42 (4) ◽  
pp. 762-771 ◽  
Author(s):  
Gerard T. Luk-Pat ◽  
Garry E. Gold ◽  
Eric W. Olcott ◽  
Bob S. Hu ◽  
Dwight G. Nishimura
Keyword(s):  
High Resolution ◽  
Atherosclerotic Plaque ◽  
In Vivo Imaging ◽  
Three Dimensional

Three-dimensional reconstruction based on images from spiral high-resolution computed tomography of the temporal bone: anatomy and clinical application

2005 ◽  
Vol 119 (9) ◽  
pp. 693-698 ◽  
Author(s):  
Beom-Cho Jun ◽  
Sun-Wha Song ◽  
Ju-Eun Cho ◽  
Chan-Soon Park ◽  
Dong-Hee Lee ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
3D Reconstruction ◽  
Temporal Bone ◽  
Three Dimensional ◽  
Image Data ◽  
Computer Assisted ◽  
Surface Rendering ◽  
High Resolution Computed Tomography

The aim of this study was to investigate the usefulness of a three-dimensional (3D) reconstruction of computed tomography (CT) images in determining the anatomy and topographic relationship between various important structures. Using 40 ears from 20 patients with various otological diseases, a 3D reconstruction based on the image data from spiral high-resolution CT was performed by segmentation, volume-rendering and surface-rendering algorithms on a personal computer. The 3D display of the middle and inner ear structures was demonstrated in detail. Computer-assisted measurements, many of which could not be easily measured in vivo, of the reconstructed structures provided accurate anatomic details that improved the surgeon’s understanding of spatial relationships. A 3D reconstruction of temporal bone CT might be useful for education and increasing understanding of the anatomical structures of the temporal bone. However, it will be necessary to confirm the correlation between the 3D reconstructed images and histological sections through a validation study.

scholarly journals The Posterior Lumbar Epidural Space: Three-Dimensional Reconstruction of High-Resolution MRI: Real and Potential Epidural Spaces and Their Content In Vivo

Pain Medicine ◽  
2019 ◽  
Vol 20 (9) ◽  
pp. 1687-1696 ◽  
Author(s):  
André P Boezaart ◽  
Alberto Prats-Galino ◽  
Olga C Nin ◽  
Anna Carrera ◽  
José Barberán ◽  
...  
Keyword(s):  
High Resolution ◽  
Epidural Space ◽  
Three Dimensional ◽  
Magnetic Resonance Images ◽  
High Definition ◽  
3D Reconstructions ◽  
Inferior Margin ◽  
Fibrous Body ◽  
Dural Sac

Abstract Objective Our aim was to study the posterior lumbar epidural space with 3D reconstructions of magnetic resonance images (MRIs) and to compare and validate the findings with targeted anatomic microdissections. Design We performed 3D reconstructions of high-resolution MRIs from seven patients and normal-resolution MRIs commonly used in clinical practice from 196 other random patients. We then dissected and photographed the lumbar spine areas of four fresh cadavers. Results From the 3D reconstructions of the MRIs, we verified that the distribution of the posterior fat pad had an irregular shape that resembled a truncated pyramid. It spanned between the superior margin of the lamina of the caudad vertebra and beyond the inferior margin to almost halfway underneath the cephalad lamina of the cranial vertebra, and it was not longitudinally or circumferentially continuous. The 3D reconstructions of the high-definition MRI also consistently revealed a prelaminar fibrous body that was not seen in most of the usually used low-definition MRI reconstructions. Targeted microdissections confirmed the 3D reconstruction findings and also showed the prelaminar tissue body to be fibrous, crossing from side to side anterior to the cephalad half of each lamina, and spanning from the dural sac to the laminae. Conclusions Three-dimensional reconstructions and targeted microdissection revealed the unique appearance of posterior fat pads and a prelaminar fibrous body. The exact consistency, presence, prevalence with age, presence in other regions, and function of this body are unknown and require further research.

scholarly journals In vivo three-dimensional evaluation of tumour hypoxia in nasopharyngeal carcinomas using FMT-CT and MSOT

2019 ◽  
Vol 47 (5) ◽  
pp. 1027-1038
Author(s):  
Wenhui Huang ◽  
Kun Wang ◽  
Yu An ◽  
Hui Meng ◽  
Yuan Gao ◽  
...  
Keyword(s):  
High Resolution ◽  
Early Stage ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Immunohistochemical Analysis ◽  
Molecular Probe ◽  
Imaging Method ◽  
Tumour Hypoxia ◽  
Imaging Strategy

Abstract Purpose Accurate evaluation of hypoxia is particularly important in patients with nasopharyngeal carcinoma (NPC) undergoing radiotherapy. The aim of this study was to propose a novel imaging strategy for quantitative three-dimensional (3D) evaluation of hypoxia in a small animal model of NPC. Methods A carbonic anhydrase IX (CAIX)-specific molecular probe (CAIX-800) was developed for imaging of hypoxia. Mouse models of subcutaneous, orthotopic, and spontaneous lymph node metastasis from NPC (5 mice per group) were established to assess the imaging strategy. A multi-modality imaging method that consisted of a hybrid combination of fluorescence molecular tomography-computed tomography (FMT-CT) and multispectral optoacoustic tomography (MSOT) was used for 3D quantitative evaluation of tumour hypoxia. Magnetic resonance imaging, histological examination, and immunohistochemical analysis were used as references for comparison and validation. Results In the early stage of NPC (2 weeks after implantation), FMT-CT enabled precise 3D localisation of the hypoxia biomarker with high sensitivity. At the advanced stage (6 weeks after implantation), MSOT allowed multispectral analysis of the biomarker and haemoglobin molecules with high resolution. The combination of high sensitivity and high resolution from FMT-CT and MSOT could not only detect hypoxia in small-sized NPCs but also visualise the heterogeneity of hypoxia in 3D. Conclusions Integration of FMT-CT and MSOT could allow comprehensive and quantifiable evaluation of hypoxia in NPC. These findings may potentially benefit patients with NPC undergoing radiotherapy in the future.

In Vivo Three-Dimensional High-Resolution Imaging of Rodent Retina with Spectral-Domain Optical Coherence Tomography

2007 ◽  
Vol 48 (4) ◽  
pp. 1808 ◽  
Author(s):  
Marco Ruggeri ◽  
Hassan Wehbe ◽  
Shuliang Jiao ◽  
Giovanni Gregori ◽  
Maria E. Jockovich ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Three Dimensional ◽  
Spectral Domain ◽  
High Resolution Imaging ◽  
Optical Coherence ◽  
Resolution Imaging

QUANTITATIVE EVALUATION OF RETINAL TUMOR VOLUME IN MOUSE MODEL OF RETINOBLASTOMA BY USING ULTRA HIGH-RESOLUTION OPTICAL COHERENCE TOMOGRAPHY

2008 ◽  
Vol 01 (01) ◽  
pp. 17-28 ◽  
Author(s):  
MARCO RUGGERI ◽  
HASSAN WEHBE ◽  
GAVRIIL TSECHPENAKIS ◽  
SHULIANG JIAO ◽  
MARIA ELENA JOCKOVICH ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Mouse Model ◽  
Tumor Volume ◽  
Automatic Segmentation ◽  
Three Dimensional ◽  
Positioning System ◽  
Optical Coherence ◽  
Spatial Registration

An ultra high resolution spectral-domain optical coherence tomography (SD-OCT) together with an advanced animal restraint and positioning system was built for noninvasive non-contact in vivo three-dimensional imaging of rodent models of ocular diseases. The animal positioning system allowed the operator to rapidly locate and switch the areas of interest on the retina. This function together with the capability of precise spatial registration provided by the generated OCT fundus image allows the system to locate and compare the same lesion (retinal tumor in the current study) at different time point throughout the entire course of the disease progression. An algorithm for fully automatic segmentation of the tumor boundaries and calculation of tumor volume was developed. The system and algorithm were successfully applied to monitoring retinal tumor growth quantitatively over time in the LHBETATAG mouse model of retinoblastoma.

scholarly journals Three-dimensional motion tracking for high-resolution optical microscopy, in vivo

2012 ◽  
Vol 246 (3) ◽  
pp. 237-247 ◽  
Author(s):  
M. BAKALAR ◽  
J.L. SCHROEDER ◽  
R. PURSLEY ◽  
T.J. POHIDA ◽  
B. GLANCY ◽  
...  
Keyword(s):  
High Resolution ◽  
Optical Microscopy ◽  
Motion Tracking ◽  
Three Dimensional

scholarly journals Individual Integration of Positron Emission Tomography and High-Resolution Magnetic Resonance Imaging

1992 ◽  
Vol 12 (6) ◽  
pp. 919-926 ◽  
Author(s):  
Helmuth Steinmetz ◽  
Yanxiong Huang ◽  
Rüdiger J. Seitz ◽  
Uwe Knorr ◽  
Gottfried Schlaug ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Three Dimensional ◽  
User Interaction ◽  
Posterior Wall ◽  
Data Set ◽  
Functional Relationships ◽  
Positron Emission ◽  
Average Residual

We have developed, validated, and employed a technique of retrospective spatial alignment and integrated display of positron emission tomographic (PET) and high-resolution magnetic resonance (MR) brain images. The method was designed to improve the anatomical evaluation of functional images obtained from single subjects. In the first computational step, alignment of PET and MR data sets is achieved by iteratively matching in three orthogonal views the outermost scalp contours derived from front-to-back projections of each data set. This procedure avoids true three-dimensional modeling, runs without user interaction, and tolerates missing parts of the head circumference in the image volume, as usually the case with PET. Thereafter, high-resolution MR sections corresponding to the PET slices are reconstructed from the spatially transformed MR data. In a phantom study of this method, PET/MR alignment of the phantom's surface was accurate with average residual misfits of 2.17 to 2.32 mm as determined in three orthogonal planes. In-plane alignment of the phantom's insertion holes was accurate with an average residual misfit of 2.30 mm. In vivo application in six subjects allowed the individual anatomical localization of regional CBF (rCBF) responses obtained during unilateral manual exploration. In each subject, the maxima of the rCBF activations in the hand area were precisely allocated to gray matter in the anterior or posterior wall of the central sulcus. The configuration of the rCBF responses closely followed the gyral structures. The technique provided a better topographical understanding of rCBF changes in subtraction images of PET activation studies. It opens the perspective for studies of structural–functional relationships in individual subjects.

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