Study of neurometabolic and behavioral alterations in rodent model of mild traumatic brain injury: a pilot study

2016 ◽  
Vol 29 (12) ◽  
pp. 1748-1758 ◽  
Author(s):  
Kavita Singh ◽  
Richa Trivedi ◽  
Seenu Haridas ◽  
Kailash Manda ◽  
Subash Khushu
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Rodent Model ◽  
Behavioral Alterations

scholarly journals Diffusion imaging of mild traumatic brain injury in the impact accelerated rodent model: A pilot study

Brain Injury ◽  
2017 ◽  
Vol 31 (10) ◽  
pp. 1376-1381 ◽  
Author(s):  
Zora Kikinis ◽  
Marc Muehlmann ◽  
Ofer Pasternak ◽  
Sharon Peled ◽  
Praveen Kulkarni ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Diffusion Imaging ◽  
Rodent Model ◽  
The Impact

scholarly journals Vergence in mild traumatic brain injury: A pilot study

2012 ◽  
Vol 49 (7) ◽  
pp. 1083 ◽  
Author(s):  
Dora Szymanowicz ◽  
Kenneth J. Ciuffreda ◽  
Preethi Thiagarajan ◽  
Diana P. Ludlam ◽  
Wesley Green ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury

Self-efficacy and acceptance of disability following mild traumatic brain injury: A pilot study

2019 ◽  
Vol 27 (5) ◽  
pp. 468-477 ◽  
Author(s):  
Einat Yehene ◽  
Gal Lichtenstern ◽  
Yirmi Harel ◽  
Eran Druckman ◽  
Yaron Sacher
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Self Efficacy

scholarly journals A pilot study on Alzheimer’s disease‐related biological and cognitive markers in dementia and history of mild traumatic brain injury

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Christian LoBue ◽  
Patricia Champagne ◽  
Catherine E Munro ◽  
Kyle B Womack ◽  
Brendan Kelley ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Cognitive Markers ◽  
History Of

scholarly journals Photophobia symptoms and visual pain thresholds in posttraumatic headache after mild traumatic brain injury

Neurology ◽  
2018 ◽  
Vol 91 (23 Supplement 1) ◽  
pp. S11.2-S11
Author(s):  
Nicholas Jarvis ◽  
Amaal J. Starling ◽  
Todd J. Schwedt
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Light Sensitivity ◽  
Fisher Exact Test ◽  
Pain Thresholds ◽  
Posttraumatic Headache ◽  
Exact Test ◽  
Wilcoxon Rank Sum Test

BackgroundLight sensitivity can be a disabling symptom in posttraumatic headache (PTH). The objective of this pilot study was to characterize photophobia symptoms and visual pain thresholds in PTH compared to healthy controls (HC).MethodsIndividuals with PTH attributed to mild traumatic brain injury (mTBI) (N = 18) and HC (N = 20), aged 18–65, were prospectively assessed using the Photosensitivity Assessment Questionnaire (PAQ), State Trait Anxiety Inventory (STAI), and Beck Depression Inventory (BDI). A progressive light stimulation device was used to quantify visual pain thresholds. Visual pain thresholds were determined by the intensity of light at which subjects first noted pain. The mean of 3 trials was considered the visual pain threshold. Two sample t-test, Wilcoxon rank sum test, χ2 test and Fisher exact test was used to compare the 2 groups for their demographics, clinical characteristics, and outcomes measures.ResultsThere were no differences in demographics including age, gender, or race. The average time since onset of PTH was 50.7 (73.6) months. Those with PTH had 15.8 (9.2) headache days per month. BDI and STAI scores were significantly higher in PTH compared to HC. Photophobia was higher in PTH compared to HC, 0.64 (0.25) vs 0.24 (0.24), p < 0.0001. Visual pain thresholds were lower in PTH (median 50.1 lux; quartiles 15.3 to 300.0) compared to HC (median 863.5 lux; quartiles 519.9 to 4,906.5; p = 0.0002).ConclusionPhotophobia symptoms are higher and visual pain thresholds are lower in PTH compared to HC. Light sensitivity is a well-known disabling symptom in PTH and this pilot study provides objective data through a validated photophobia scale and visual pain thresholds to characterize light sensitivity. Additional studies are needed to confirm this data, to compare acute to persistent PTH, to compare PTH to other headache disorders, and to determine if photophobia and visual pain thresholds will improve with intervention.

scholarly journals Pilot Study of Neurological Soft Signs and Depressive and Postconcussive Symptoms During Recovery From Mild Traumatic Brain Injury (mTBI)

2015 ◽  
Vol 27 (3) ◽  
pp. 199-205 ◽  
Author(s):  
Mark S. Greenberg ◽  
Nellie E. Wood ◽  
Justin D. Spring ◽  
Tamara V. Gurvits ◽  
John T. Nagurney ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pilot Study ◽  
Mild Traumatic Brain Injury ◽  
Neurological Soft Signs ◽  
Postconcussive Symptoms
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