scholarly journals Vertical gradients in regional alveolar oxygen tension in supine human lung imaged by hyperpolarized3He MRI

2014 ◽  
Vol 27 (12) ◽  
pp. 1439-1450 ◽  
Author(s):  
Hooman Hamedani ◽  
Hoora Shaghaghi ◽  
Stephen J. Kadlecek ◽  
Yi Xin ◽  
Biao Han ◽  
...  
2011 ◽  
Vol 67 (5) ◽  
pp. 1332-1345 ◽  
Author(s):  
Hooman Hamedani ◽  
Stephen J. Kadlecek ◽  
Kiarash Emami ◽  
Nicholas N. Kuzma ◽  
Yinan Xu ◽  
...  

1983 ◽  
Vol 11 (11) ◽  
pp. 888-891 ◽  
Author(s):  
LUIS V. PERIS ◽  
JESÚS H. BOIX ◽  
JOSÉ V. SALOM ◽  
VICENTE VALENTIN ◽  
DOLORES GARCIA ◽  
...  

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Federico Formenti ◽  
Nikhil Bommakanti ◽  
Rongsheng Chen ◽  
John N. Cronin ◽  
Hanne McPeak ◽  
...  

1964 ◽  
Vol 206 (4) ◽  
pp. 891-897 ◽  
Author(s):  
J. Hedley-Whyte ◽  
M. B. Laver ◽  
H. H. Bendixen

The rate and magnitude of the effects of the pressure-volume history of the lungs on the degree of physiologic shunting (pulmonary venous admixture) were investigated in 20 dogs, anesthetized and curarized. Atelectasis was promoted by decreasing end-expiratory transpulmonary pressure. Ventilation was with 100% oxygen using a constant-volume pump at a frequency of 20 breaths/min. The rates of increase or decrease in the physiologic shunt and of the gradients between derived alveolar oxygen tension and directly measured arterial oxygen tension (A-aD) showed a variation controlled by the pressure-volume history of the lungs. The physiologic shunts produced varied between 0.5% and 80% of the cardiac output. The interrelationships of the components of the shunt equation were studied and their relative value in predicting atelectasis was discussed. The data obtained were related to other observations made in anesthetized man.


1961 ◽  
Vol 16 (6) ◽  
pp. 1043-1046 ◽  
Author(s):  
Ferdinand Kreuzer

Catheter oxygen pressure (PO2) electrodes for continuous recording of blood oxygen tension in vivo were inserted into the aorta of dogs anesthetized with pentobarbital and ventilated with constant volume and frequency. Femoral arteries were cannulated for pressure recording and arterial sampling for arterial oxygen tension (PaO02) calibration by polarography. Epinephrine in doses between 0.002 and 133 μg/kg and norepinephrine between 1.25 and 133 μg/kg were injected intravenously. With both agents two types of PaO02 response, without change in alveolar oxygen tension (PaO02) were observed: Type I occurred with high doses and consisted of three phases, a rise of 10—20 mm Hg, then a decrease of up to 100 mm Hg, and eventually an increase of 15–30 mm Hg. Type II was found with doses below 5 μg/kg and showed only a PaO02 increase of 10—70 mm Hg. Doses below 0.05 μg/kg were without effect. The reactions were most pronounced with breathing of 100% oxygen. This suggests an influence of the agents on true venous admixture. The effects might be due to a differential action on pulmonary and systemic (bronchial) circulation, perhaps combined with differences of action on the two sides of the heart and blood shifts. Note: With the Assistance of J. S. Picken Submitted on September 26, 1960


1978 ◽  
Vol 57 (6) ◽  
pp. 744 ◽  
Author(s):  
G. B. Drummond

1987 ◽  
Vol 67 (3) ◽  
pp. A110-A110 ◽  
Author(s):  
W. E. Johnston ◽  
J. Vinten-Johansen ◽  
D. L. Bowton ◽  
R. A. Strickland ◽  
R. L. Royster

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