scholarly journals Minimum important difference for validated instruments in women with urge incontinence

2011 ◽  
Vol 30 (7) ◽  
pp. 1319-1324 ◽  
Author(s):  
Keisha Y. Dyer ◽  
Yan Xu ◽  
Linda Brubaker ◽  
Ingrid Nygaard ◽  
Alayne Markland ◽  
...  
Keyword(s):  
Urge Incontinence ◽  
Minimum Important Difference

scholarly journals Diagnostic Potential of Low Serum Platelet, Albumin and Prolong PT-INR for Overactive Bladder and Nocturia in Chronic Hepatitis-Related Liver Cirrhosis

2021 ◽  
Vol 10 (13) ◽  
pp. 2838
Author(s):  
Po-Heng Chuang ◽  
Yi-Huei Chang ◽  
Po-Jen Hsiao ◽  
Eric Chieh-Lung Chou
Keyword(s):  
Liver Cirrhosis ◽  
Overactive Bladder ◽  
Serum Albumin ◽  
Urge Incontinence ◽  
Albumin Level ◽  
Chronic Viral Hepatitis ◽  
Study Cohort ◽  
Diagnostic Potential ◽  
Fluid Redistribution ◽  
Low Serum

Overactive bladder (OAB) is defined as urgency, usually with frequency, nocturia, and incontinence. Patients with liver cirrhosis often present with urinary complaints. The possible reason for this is fluid redistribution, which may induce OAB resulting from portal hypertension and ascites. We conducted this study to investigate predictors of OAB in cirrhotic patients. A total of 164 patients with chronic viral hepatitis-related liver cirrhosis were enrolled and 158 (96.3%) completed the Overactive Bladder Symptoms Score (OABSS) questionnaire. Age, severity of liver cirrhosis, comorbidities, serum sodium level, use of diuretics, body mass index and renal function were also recorded. In the study cohort, the prevalence of OAB was 31.01% and the prevalence of urge incontinence (OAB wet) was 18.3%. Patients with an urgency score ≥2 in OABSS had a significantly lower platelet level (p = 0.025) regardless of the use of diuretics. In addition, 98 patients (62%) with nocturia and 29 patients (18%) with urge incontinence had significantly lower levels of serum albumin (p = 0.028 and 0.044, respectively). In conclusion, patients with liver cirrhosis have a high prevalence of overactive bladder. A low platelet and low serum albumin level in these patients may be predictors for overactive bladder. And longer PT-INR is also a possible biomarker for nocturia.

scholarly journals Estimating the minimum important difference in the DEMQOL instrument in people with dementia

2021 ◽  
Author(s):  
Ellen C. Lee ◽  
Jessica Wright ◽  
Stephen J. Walters ◽  
Cindy L. Cooper ◽  
Gail A. Mountain
Keyword(s):  
Quality Of Life ◽  
Controlled Trial ◽  
Minimum Important Difference ◽  
Absolute Change ◽  
People With Dementia ◽  
Related Quality ◽  
Registration Number ◽  
Clinically Significant ◽  
Randomised Controlled

Abstract Purpose The Dementia-Related Quality of Life (DEMQOL) measure and the DEMQOL-Utility Score (DEMQOL-U) are validated tools for measuring quality of life (QOL) in people with dementia. What score changes translate to a clinically significant impact on patients’ lives was unknown. This study establishes the minimal important differences (MID) for these two instruments. Methods Anchor-based and distribution-based methods were used to estimate the MID scores from patients enrolled in a randomised controlled trial. For the anchor-based method, the global QOL (Q29) item from the DEMQOL was chosen as the anchor for DEMQOL and both Q29 and EQ-5D for DEMQOL-U. A one category difference in Q29, and a 0.07 point difference in EQ-5D score, were used to classify improvement and deterioration, and the MID scores were calculated for each category. These results were compared with scores obtained by the distribution-based methods. Results A total of 490 people with dementia had baseline DEMQOL data, of these 386 had 8-month data, and 344 had 12-month DEMQOL data. The absolute change in DEMQOL for a combined 1-point increase or decrease in the Q29 anchor was 5.2 at 8 months and 6.0 at 12 months. For the DEMQOL-U, the average absolute change at 8 and 12 months was 0.032 and 0.046 for the Q29 anchor and 0.020 and 0.024 for EQ-5D anchor. Conclusion We present MID scores for the DEMQOL and DEMQOL-U instruments obtained from a large cohort of patients with dementia. An anchored-based estimate of the MID for the DEMQOL is around 5 to 6 points; and 0.02 to 0.05 points for the DEMQOL-U. The results of this study can guide clinicians and researchers in the interpretation of these instruments comparisons between groups or within groups of people with dementia. Trial Registration Number and date of registration: ISRCTN17993825 on 11th October 2016.

scholarly journals Prevalence of Urinary Incontinence in Women

2020 ◽  
Vol 33 (1) ◽  
pp. 59-62
Author(s):  
Lubna Yasmin ◽  
Ferdousi Begum
Keyword(s):  
Urinary Incontinence ◽  
Stress Incontinence ◽  
Urge Incontinence ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mixed Incontinence ◽  
Medical College

Objective: The objectives of the study were to find out the prevalence of urinary incontinencein women. Materials and Methods: A cross sectional study was conducted on five hundred one (501)women older than 18 years of age who were admitted in department of obstetrics andgynaecology of Shaheed Suhrawardi Medical College and Hospital from April to December2009, answered a questionnaire about urinary incontinence. They were grouped accordingto presence or absence of urinary incontinence (incontinent and continent) and type ofincontinence present (urge, stress and mixed). Results: Urinary incontinence was found in 104(20.8%) women, out of which 25 (24%)suffered from stress incontinence only, 21 (20.2%) suffered from urge incontinence and58(55.8%) suffered mixed incontinence. Conclusions: One in five women older than 18 years of age suffer from one or other formof urinary Incontinence. Bangladesh J Obstet Gynaecol, 2018; Vol. 33(1) : 59-62

scholarly journals Brain Mechanisms Underlying Urge Incontinence and its Response to Pelvic Floor Muscle Training

2015 ◽  
Vol 194 (3) ◽  
pp. 708-715 ◽  
Author(s):  
Derek Griffiths ◽  
Becky Clarkson ◽  
Stasa D. Tadic ◽  
Neil M. Resnick
Keyword(s):  
Pelvic Floor ◽  
Urge Incontinence ◽  
Pelvic Floor Muscle Training ◽  
Pelvic Floor Muscle ◽  
Muscle Training

Urinary Incontinence and Overactive Bladder Syndrome

2018 ◽  
Author(s):  
Kristie A. Greene ◽  
Lennox Hoyte
Keyword(s):  
Urinary Incontinence ◽  
Overactive Bladder ◽  
Stress Incontinence ◽  
Urge Incontinence ◽  
Valsalva Maneuver ◽  
Abdominal Pressure ◽  
Sudden Increase ◽  
Overactive Bladder Syndrome ◽  
Urinary Frequency ◽  
Mixed Incontinence

Urinary incontinence falls into two broad categories: stress incontinence and urge incontinence. Stress urinary incontinence occurs when urethral closure pressure cannot increase sufficiently to compensate for a sudden increase in intra-abdominal pressure, as from a cough or Valsalva maneuver. Urge urinary incontinence occurs when an unintended bladder contraction creates an insuppressible urge to void, leading to urinary leakage. When women have signs and/or symptoms of both stress and urge incontinence, it is referred to as mixed urinary incontinence. Overactive bladder syndrome is defined by the Standardization Subcommittee of the International Continence Society (ICS) as urinary urgency, with or without urge incontinence and usually with frequency and nocturia. Nocturia, which is often associated with urinary frequency, is defined as a need to urinate that awakens the person during the night. This chapter discusses the epidemiology and physiology of urinary incontinence and overactive bladder syndrome in women, as well as diagnosis and treatment. Tables list foods and beverages that may cause urinary frequency and urgency; features of urge incontinence, stress incontinence, and mixed incontinence; American Urologic Association (AUA) guidelines regarding level of evidence and indications for adult urodynamics; and currently available antimuscarinic drugs and their dosages, selectivity, efficacy, and side effects. Figures depict the journal of someone with mixed incontinence, a typical urodynamics suite, a urodynamic study of someone with detrusor overactivity, incontinence pessaries, and transobturator and retropubic slings. This review contains 5 figures, 5 tables, and 44 references.

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