Pulmonary hyperpolarized129Xe morphometry for mapping xenon gas concentrations and alveolar oxygen partial pressure: Proof-of-concept demonstration in healthy and COPD subjects

2014 ◽  
Vol 74 (6) ◽  
pp. 1726-1732 ◽  
Author(s):  
A. Ouriadov ◽  
A. Farag ◽  
M. Kirby ◽  
D.G. McCormack ◽  
G. Parraga ◽  
...  
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Proof Of Concept ◽  
Alveolar Oxygen

Alveolar oxygen partial pressure and oxygen depletion rate mapping in rats using3He ventilation imaging

2007 ◽  
Vol 57 (2) ◽  
pp. 423-430 ◽  
Author(s):  
Katarzyna Cieślar ◽  
Vasile Stupar ◽  
Emmanuelle Canet-Soulas ◽  
Sophie Gaillard ◽  
Yannick Crémillieux
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Oxygen Depletion ◽  
Ventilation Imaging ◽  
Depletion Rate ◽  
Alveolar Oxygen

Effect of varying alveolar oxygen partial pressure on diffusing capacity for nitric oxide and carbon monoxide, membrane diffusing capacity and lung capillary blood volume

1991 ◽  
Vol 81 (6) ◽  
pp. 759-765 ◽  
Author(s):  
C. D. R. Borland ◽  
Y. Cox
Keyword(s):  
Nitric Oxide ◽  
Carbon Monoxide ◽  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Diffusing Capacity ◽  
Pulmonary Capillary ◽  
Capillary Blood Volume ◽  
Novel Method ◽  
The Mean ◽  
Alveolar Oxygen

1. To examine the effect of varying oxygen partial pressure (Pao2) on nitric oxide (DLNO) and carbon monoxide (DLCO) diffusing capacity (transfer factor), 10 subjects performed combined DLCO/DLNO measurements with the inspired mixture made up with three different oxygen concentrations (25%, 18% and 15%) to give Pao2 values of 12–20 kPa. 2. A novel method is described for calculating membrane diffusing capacity (DM) and pulmonary capillary volume (Qc) from DLNO and DLCO. 3. The mean DMCO was 52.89 mmol min−1 kPa−1 and Qc was 0.056 litre. Reducing Pao2 from 20 to 12 kPa resulted in an increase in DLCO = −0.124 (O2%) + 11.67 (P < 0.001) and a fall in DLNO = 0.538 (O2%) + 32.01 (P < 0.001) and a fall in DLNO/DLCO = 0.107 (O2%) + 2.52 (P < 0.001). DM (P = 0.59) and Qc (P = 0.64) also tended to fall with falling Pao2. 4. It appears more likely that the minor reduction in DLNO that we have observed with falling Pao2 is due to diffusion rather than reaction limitation.

Arterial-alveolar oxygen partial pressure ratio

1986 ◽  
Vol 14 (2) ◽  
pp. 153-154 ◽  
Author(s):  
JEAN-PAUL VIALE ◽  
CARLISLE J. PERCIVAL ◽  
GUY ANNAT ◽  
BERNARD ROUSSELET ◽  
JEAN MOTIN
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Pressure Ratio ◽  
Alveolar Oxygen ◽  
Partial Pressure Ratio

Stability of the arterial/alveolar oxygen partial pressure ratio

1979 ◽  
Vol 7 (6) ◽  
pp. 267-272 ◽  
Author(s):  
ROBERT GILBERT ◽  
J. H. AUCHINCLOSS ◽  
MITCHELL KUPPINGER ◽  
M. VARKEY THOMAS
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Pressure Ratio ◽  
Alveolar Oxygen ◽  
Partial Pressure Ratio

scholarly journals Measurement of alveolar oxygen partial pressure in the rat lung using Carr-Purcell-Meiboom-Gill spin-spin relaxation times of hyperpolarized 3 He and 129 Xe at 74 mT

2010 ◽  
Vol 64 (5) ◽  
pp. 1484-1490 ◽  
Author(s):  
Ryan J. Kraayvanger ◽  
Christopher P. Bidinosti ◽  
William Dominguez-Viqueira ◽  
Juan Parra-Robles ◽  
Matthew Fox ◽  
...  
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Spin Relaxation ◽  
Relaxation Times ◽  
Rat Lung ◽  
Alveolar Oxygen

scholarly journals Proof of Concept Study to Assess the Influence of Oxygen Partial Pressure in Capillary Blood on SMBG Measurements

2019 ◽  
Vol 13 (6) ◽  
pp. 1105-1111
Author(s):  
Annette Baumstark ◽  
Stefan Pleus ◽  
Nina Jendrike ◽  
Christina Liebing ◽  
Rolf Hinzmann ◽  
...  
Keyword(s):  
Oxygen Partial Pressure ◽  
Partial Pressure ◽  
Linear Regression Analysis ◽  
Glucose Monitoring ◽  
Capillary Blood ◽  
Blood Glucose Monitoring ◽  
Proof Of Concept ◽  
Blood Samples ◽  
Concept Study ◽  
Measurement Results

Background: Measurement results provided by blood glucose monitoring systems (BGMS) can be affected by various influencing factors. For some BGMS using glucose oxidase (GOx)-based test strips, one of these factors is the oxygen partial pressure (pO2) of the applied blood sample. Because assessing the potential influence of pO2 when measuring capillary blood samples is not straight-forward, we performed a proof of concept study. Method: Influence of pO2 was investigated for two GOx-based BGMS (BGMS A and B). Measurement results of the GOx-based BGMS were compared with measurement results from a pO2-independent BGMS (BGMS C). A total of 119 samples from 60 subjects were measured, twice with BGMS C, then 6 times each with BGMS A and BGMS B or vice versa, and again twice with BGMS C. Immediately afterward, pO2 was determined. Linear regression analysis based on relative differences between results from BGMS A or BGMS B and results from BGMS C was performed to estimate the degree of pO2 influence. Results: The relative bias between the lowest and highest pO2 values differed by 14.3% for BGMS A, indicating a pO2 influence that might be clinically relevant, and by 9.7% for BGMS B, indicating that pO2 influence may be too small to be reliably detected because of the BGMS’ imprecision. Conclusions: This proof of concept study showed that with the procedures used, a potentially clinically relevant influence of pO2 in capillary blood samples on GOx-based BGMS could be detected. Further larger-scale studies are needed to verify this influence.

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